Belonging to a cluster of drugs known as PPIs, Omeprazole 20mg Capsule is used for reducing the acid content in the stomach. This drug treats duodenal or gastric ulcers, Gastroesophageal Reflux Disease (GERD), inflammation of the esophagus, and conditions wherein the stomach secretes excess acid.
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Caution is advised when consuming alcohol with Losectil 20. Please consult your doctor.
The safety of Losectil 20 during pregnancy is uncertain due to limited human studies and potential harm to the developing fetus based on animal studies. Before taking it, consult with your doctor, who will assess the benefits and risks.
Losectil 20 is probably unsafe to use during breastfeeding. Limited data suggests that the drug may pass into the breastmilk and harm the baby.
The impact of Losectil 20 on driving ability is unclear. If you experience any symptoms that affect concentration and reaction time, refrain from driving.
Losectil 20 is safe to use in patients with kidney disease. No dose adjustment of Losectil 20 is recommended.
Patients with severe liver disease should use Losectil 20 with caution, and dose adjustment may be necessary. Your doctor should be consulted. A lower dose may be recommended for those with long-term medication needs and liver disease.
Treatment of -
Losectil 20 Capsule effectively lowers the amount of acid produced in the stomach by irreversibly binding to and inhibiting the hydrogen-potassium ATPase pump that resides on the lining of the digestive tract. This kind of action helps to reduce vomiting and promote the healing of damaged stomach tissue in ulcers.
If you miss a dose of Losectil 20 Capsule, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
The common side effects of Losectil 20 include headache, abdominal pain, diarrhea, nausea, vomiting, flatulence, dizziness, upper respiratory infection, acid regurgitation, constipation, rash, and cough. Potentially fatal side effects include anaphylaxis, hepatotoxicity, agranulocytosis, gastric polyps, hip fracture, atrophic gastritis, interstitial nephritis, pancreatitis, rhabdomyolysis, taste perversion, abnormal dreams, toxic epidermal necrolysis.
Used in the treatment of the following conditions:
Losectil 20 Capsule is a proton pump inhibitor (PPI) that inhibits the final step of gastric acid secretion by blocking the H+/K+ ATPase enzyme system in the gastric parietal cell.
Losectil 20 should be taken one hour before a meal, preferably in the morning. The dose will depend on the underlying condition and the patient's response to the medicine. The usual adult dose for peptic ulcer disease is 20-40 mg/day for 4-8 weeks, and maintenance is 10-20 mg/day. The dosage for H. pylori infection is in combination with antibiotics, and the duration is 7-10 days. The dose for acid reflux is 20 mg/day for 4 weeks, which may continue for another 4-8 weeks if necessary.
Take Losectil 20 Capsules as advised by your physician. Swallow Losectil 20 Capsule with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of Losectil 20 Capsule for you depending on your age, body weight, and disease condition
Interaction with Alcohol: The interaction between Losectil 20 Capsule and alcohol is unknown. It is advisable to consult your doctor before consuming alcohol while taking this medication.
Interaction with Lab Test: Information about interactions with lab tests is not available. It's always recommended to inform your healthcare provider about all medications you are taking before undergoing any lab tests.
Interaction with Ketoconazole: Losectil 20 Capsule may interfere with the desired effect of ketoconazole and other antifungal agents. Inform your doctor if you are taking either of these medications to explore safer alternatives.
Interaction with Methotrexate: It is not recommended to take Losectil 20 Capsule with methotrexate. This combination can increase the concentration of methotrexate in the blood and lead to serious side effects. Inform your doctor if you are taking these medicines together, and an alternative medicine may be considered based on your clinical condition.
Interaction with Warfarin: Caution is advised when using Losectil 20 Capsule with Warfarin, a blood thinner. Regular monitoring of prothrombin time, unusual bleeding, and the presence of blood in urine is necessary. Dose adjustments should be made under the supervision of a doctor.
Interaction with Nelfinavir: The desired effect of antiviral medications like nelfinavir may not be achieved when taken with Losectil 20 Capsules. Inform your doctor if you are taking these medicines together, and an alternative medicine may be considered based on your clinical condition.
Interaction with Osteoporosis: Losectil 20 Capsule, especially at high doses and during long-term therapy, may increase the risk of bone fractures. If you are at risk of developing osteoporosis-related fractures, caution should be exercised, and lower doses for a shorter duration may be considered.
Drug-Food Interactions: Losectil 20 Capsule may interact with St. John's wort, a plant used as an antidepressant. Avoid taking St. John's wort with Losectil 20 Capsule as it may affect the working of the medication.
Drug-Disease Interactions: Losectil 20 Capsule should not be given to patients with C. difficile-induced colitis, liver disease, bone fractures, low vitamin B12 levels (anemia), or low magnesium levels (hypomagnesemia).
Losectil 20 is contraindicated in patients with a known hypersensitivity to any of its components.
There are no adequate and well-controlled studies with Losectil 20 in pregnant women. It may be unsafe to use during pregnancy and breastfeeding. The developmental and health benefits of breastfeeding should be considered along with the mother's clinical need for therapy and any potential adverse effects on the breastfed infant.
In case of an overdose, seek immediate medical attention. The symptoms of an overdose may include confusion, drowsiness, blurred vision, dry mouth, sweating, flushing, headache, and rapid heartbeat.
Store at room temperature, away from heat and moisture. Keep out of reach of children.
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