Omeprazole offers significant therapeutic gains in the treatment of acid-related diseases. Healing rates are high in duodenal ulcer, gastric ulcer, and erosive reflux oesophagitis; acid production is controlled effectively in Zollinger-Ellison Syndrome and symptom relief is prompt and sustained in all indications. Less clear-cut indications where benefit might be expected but where data are limited include:
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Caution is advised when consuming alcohol with PPI 20. Please consult your doctor.
PPI 20 may be unsafe to use during pregnancy. Although there are limited studies in humans, animal studies have shown harmful effects on the developing baby. Your doctor will weigh the benefits and any potential risks before prescribing it to you. Please consult your doctor.
SPPI 20mg Capsule is probably unsafe to use during breastfeeding. Limited human data suggests that the drug may pass into the breastmilk and harm the baby.
It is not known whether PPI 20mg Capsule alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react.
PPI 20mg Capsule is safe to use in patients with kidney disease. No dose adjustment of the PPI 20mg Capsule is recommended.
PPI 20mg Capsule should be used with caution in patients with severe liver disease. A dose adjustment of PPI 20mg Capsule may be needed. Please consult your doctor. A lower dose may be advised in patients with liver disease and who have to take this medicine for a long time.
PPI 20mg Capsule is a proton pump inhibitor (PPI). It works by reducing the amount of acid in the stomach which helps in the relief of acid-related indigestion and heartburn.
Omeprazole is used to treat the following conditions:
Omeprazole, a substituted benzimidazole, is a stomach acid secretion inhibitor. It reduces stomach acid secretion by inhibiting the enzyme system of hydrogen-potassium-adenosine triphosphatase (H+/K+ ATPase) in the gastric parietal cell. The antisecretory action begins within one hour of oral administration, with the greatest impact happening within two hours and secretion suppression lasting up to 72 hours. When the medication is stopped, secretory activity gradually recovers over 3 to 5 days.
Oral-
Gastro-Esophageal Reflux Disease:
Benign Gastric and Duodenal Ulcer:
NSAID-associated Duodenal or Gastric Ulcer:
Long-term management of Acid Reflux Disease:
Acid-related Dyspepsia:
Prophylaxis of Acid Aspiration:
Zollinger-Ellison Syndrome:
Helicobacter Pylori Eradication Regimen in Peptic Ulcer Disease:
Pediatric use in severe ulcerating reflux esophagitis (Child>1 year):
Omeprazole can cause diazepam, warfarin, and phenytoin to be eliminated more slowly. When Omeprazole is added to the therapy, the amount of warfarin or phenytoin may need to be reduced. Omeprazole does not appear to interact with theophylline, propranolol, or antacids.
Omeprazole is not recommended for people who have a history of hypersensitivity to any of the formulation's components.
Keep away from light and heat in a dry area. Keep out of children's reach.
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