Linatab E 5/10mg Tablet | Empagliflozin | Linagliptin | ePharma
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Linatab E 5/10mg Tablet 10pcs

Generic: Empagliflozin + Linagliptin

Type: Tablet

Pack Size: 10 Pcs

Empagliflozin+Linagliptin is used to manage:

  • Type II diabetes mellitus in adults along with proper diet and exercise
  • Heart problems among patients having both diabetes and heart problems

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Discount Price: ৳ 279
MRP: ৳ 300 7% Off

⪼ Save  ৳: 21  in this Product


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✅ Description:

Linatab E 5/10mg Tablet, comprising Empagliflozin and Linagliptin, falls under the category of antidiabetic agents. It is primarily prescribed to manage type II diabetes mellitus in adults when conventional methods like diet, exercise, and other medications fail to sufficiently control blood sugar levels. This medication is typically used in conjunction with a proper diet and regular exercise regime to achieve optimal results.

Additionally, Linatab E 5/10mg Tablet may also be employed in the management of heart complications in individuals with both diabetes and heart issues. It's crucial to adhere to proper hygiene practices and foot care routines as recommended by your doctor while undergoing treatment with Linatab E 5/10mg Tablet. Regular monitoring of blood glucose levels, as directed by your healthcare provider, is essential.

Before initiating treatment with Linatab E 5/10mg Tablet, inform your doctor about any existing liver or kidney problems. Additionally, if you have recently experienced severe dehydration due to excessive vomiting or diarrhea, it's important to disclose this to your doctor as a precautionary measure.

Notably, Linatab E 5/10mg Tablet is not suitable for patients with Type I diabetes, alcoholism, or diabetic ketoacidosis.

Safety Advices


Alcohol
UNSAFE

It's advisable to avoid alcohol consumption while taking Linatab E 5/10mg Tablet to minimize the risk of potential unwanted side effects.


Pregnancy
CONSULT YOUR DOCTOR

Avoid using Linatab E 5/10mg Tablet during pregnancy unless specifically recommended by your doctor due to uncertainty about its effects on the unborn baby.


Breastfeeding
CONSULT YOUR DOCTOR

Consult your doctor before using Linatab E 5/10mg Tablet while breastfeeding as it is not known whether the medication passes through breast milk.


Driving
CAUTION

While Linatab E 5/10mg Tablet is not expected to affect your ability to drive or operate heavy machinery, refrain from doing so if you experience any side effects that impair your alertness or coordination.


CONSULT YOUR DOCTOR

Use Linatab E 5/10mg Tablet with caution in patients with serious kidney problems. Consult your doctor before starting the medication if you have kidney issues.


CONSULT YOUR DOCTOR

Linatab E 5/10mg Tablet is contraindicated in patients with severe liver problems. Avoid using it if you have such conditions and consult your doctor for alternative treatment options.

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✔️ How does Linatab E 5/10mg Tablet work?

Empagliflozin and linagliptin both act through different mechanisms to improve glycemic control in patients with type 2 diabetes mellitus:

Empagliflozin inhibits the sodium-glucose co-transporter 2 (SGLT2) in the kidneys. SGLT2 is responsible for reabsorbing glucose from the glomerular filtrate back into the bloodstream. By inhibiting SGLT2, empagliflozin reduces the reabsorption of filtered glucose by the kidneys, thereby increasing the amount of glucose excreted in the urine. This leads to a decrease in blood glucose levels.

Linagliptin is an inhibitor of dipeptidyl peptidase-4 (DPP-4), an enzyme that degrades incretin hormones such as glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP). By inhibiting DPP-4, linagliptin increases the concentration of active incretin hormones, which stimulate the release of insulin from pancreatic beta cells in a glucose-dependent manner. Additionally, GLP-1 inhibits glucagon secretion from pancreatic alpha cells, thereby reducing hepatic glucose output.

✔️ Side Effects of Linatab E 5/10mg Tablet
  • Unusual tiredness or weakness
  • Nausea and vomiting
  • Inflammation of pancreas
  • Blurred vision
  • Bladder pain
  • Bloody or cloudy urine
  • Difficult or painful urination
  • Lower back pain
  • Fast heartbeat
  • Headache
  • Itching and skin rash
✔️ Quick Suggestions:
  • This combination medicine is prescribed to control blood sugar levels better than either medication alone. It may also reduce the risk of cardiovascular events like heart attacks or heart failure.
  • Continue exercising regularly, eating a healthy diet, and taking any other diabetes medicines prescribed by your doctor.
  • To reduce the chance of upset stomach, take Empagliflozin + Linagliptin with food.
  • Practice good genital hygiene to prevent yeast or urinary tract infections, which may be associated with this medication.
  • Be aware that this medication may cause your body to lose too much fluid (dehydration) or increase urination frequency. Drink plenty of water, stay hydrated, and rise slowly after sitting or lying down.
  • Be cautious about hypoglycemia (low blood sugar) when using Empagliflozin + Linagliptin with other antidiabetic medicines, alcohol, or if meals are delayed or missed. Check your blood sugar regularly and carry sugary food or fruit juice in case of hypoglycemia symptoms like cold sweats, pale skin, tremors, or anxiety.
✔️ Recommended Dose

The recommended dose of Linagliptin is 5mg once daily. When adding Linagliptin to metformin, the dose of metformin should be maintained, and Linagliptin should be administered concurrently. In combination with a sulphonylurea or insulin, a lower dose of the sulphonylurea or insulin may be considered to mitigate the risk of hypoglycemia.

✔️ For Renal impairment Patients:

For patients with renal impairment, no dose adjustment for Linagliptin is necessary. Similarly, pharmacokinetic studies suggest that no dose adjustment is required for patients with hepatic impairment, although clinical experience in this population is limited. No dose adjustment is necessary based solely on age, but caution should be exercised when treating elderly patients, particularly those over 80 years old.

✔️ For children and adolescents:

The safety and efficacy of Linagliptin in children and adolescents have not been established yet. Linagliptin can be taken with or without a meal at any time of the day. If a dose is missed, it should be taken as soon as remembered, but a double dose should not be taken on the same day.

✔️ Overdose Effects of Linatab E 5/10mg Tablet

In controlled clinical trials involving healthy subjects, single doses of up to 600 mg of Linagliptin were generally well tolerated. However, there is no experience with doses above 600 mg in humans. In the event of an overdose, standard supportive measures should be employed. These may include removing unabsorbed material from the gastrointestinal tract, clinical monitoring, and implementing appropriate clinical interventions if necessary.

✔️ Interactions with Medicine:
  • Aripiprazole
  • Clozapine
  • Dexamethasone
  • Gatifloxacin
  • Bexarotene
✔️ Disease Interactions:
  • Linatab E 5/10mg Tablet should be used cautiously if you have hypotension (low blood pressure) as it may worsen your condition. Follow your doctor's instructions carefully.
  • There's a risk of pancreatitis (inflammation of the pancreas) with Linatab E 5/10mg Tablet use. If you have a history of pancreatitis or experience symptoms like abdominal pain, nausea, vomiting, or abdominal tenderness, inform your doctor promptly.
  • Use Linatab E 5/10mg Tablet cautiously if you have kidney disease, as it may worsen your condition. Make sure to discuss your kidney health with your doctor before starting this medication.
✔️ Contraindications

Hypersensitivity to the active substance or any of the excipients.

✔️ Pregnancy & Lactation
  • The use of Linagliptin has not been studied in pregnant women. It's advisable to avoid using Linagliptin during pregnancy unless the potential benefits outweigh the risks.
  • The risk to breastfed infants cannot be ruled out. A decision should be made whether to discontinue breastfeeding or discontinue Linagliptin therapy, taking into account the benefits of breastfeeding for the child and the benefits of therapy for the woman.
✔️ Precaution & Warnings:
  • There have been reports of acute pancreatitis, including fatal cases, associated with Linagliptin. If pancreatitis is suspected, discontinue Linagliptin promptly.
  • Assess and correct volume status before initiating Linagliptin in patients with renal impairment, the elderly, those with low systolic blood pressure, and those on diuretics. Monitor for signs and symptoms of hypotension during therapy.
  • Monitor renal function regularly during Linagliptin therapy, especially in patients with an estimated glomerular filtration rate (eGFR) below 60 mL/min/1.73 m2.
  • Consider reducing the dose of insulin secretagogues or insulin to minimize the risk of hypoglycemia when initiating Linagliptin therapy.
  • Monitor for genital mycotic infections and treat them as appropriate.
  • Monitor for urinary tract infections and treat as appropriate.
  • Discontinue Linagliptin promptly if hypersensitivity reactions occur. Assess for other potential causes, initiate appropriate monitoring and treatment, and consider alternative diabetes treatments.
  • Monitor and treat elevated LDL-cholesterol levels as appropriate during Linagliptin therapy.
  • There's no conclusive evidence from clinical studies demonstrating macrovascular risk reduction with Linagliptin or any other antidiabetic drug.
✔️ Storage Conditions:
  • Keep Linatab E 5/10mg Tablet out of the sight and reach of children
  • Store Linatab E 5/10mg Tablet below 30°C
Frequently Asked Questions (FAQ)

A: GLinatab E 5/10mg Tablet is used to manage type II diabetes mellitus in adults, along with proper diet and exercise.

A: No, follow the prescribed dose for optimal effectiveness.

A: Common side effects include vaginal infection, sore throat, cough, increased urination, thirst, and constipation.

A: Yes, regular kidney function tests are advised as a precaution.

A: Consult your doctor for advice on combining these medications.

A: Consult your doctor before taking any medication along with Linatab E 5/10mg Tablet.

A: No, do not stop without consulting your doctor, as it may worsen symptoms.

A: Take the missed dose promptly unless it's close to the next scheduled dose. Do not double dose.

A: Take Linatab E 5/10mg Tablet as prescribed by your doctor, as diabetes is a chronic condition.

A: Consume sugary snacks immediately and consult your doctor if symptoms persist.

A: Dehydration may lead to kidney damage. Stay hydrated and consult your doctor if unable to drink fluids.

A: Linatab E 5/10mg Tablet contains Empagliflozin and Linagliptin, which work by eliminating excess sugars through urine and stimulating insulin release, respectively, thereby controlling blood sugar levels.

A: Yes, it can. Maintain a balanced diet and hydration to manage constipation.

A: Use in pregnant women is not recommended without consulting a physician.

A: Linatab E 5/10mg Tablet and metformin are both used to manage type 2 diabetes but work differently. The choice depends on individual factors and medical history.

A: Linatab E 5/10mg Tablet can be taken with or without meals, at the same time daily.
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Check our pricing section for Linatab E 5/10mg Tablet 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
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