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Esoral 20 is a medication that reduces the amount of acid produced in the stomach, used to treat heartburn, acid reflux, and stomach ulcers. It should be taken as prescribed by a doctor, with the lowest effective dose for the shortest duration necessary. Common side effects include headache, constipation, and stomach pain. Serious side effects are rare but require immediate medical attention. It may increase the risk of bone fractures if taken for a long time. Foods that worsen symptoms should be avoided, and alcohol consumption should be limited. Esoral 20 is not suitable for everyone, and pregnant or breastfeeding women should consult a doctor before taking it. The medication may cause dizziness, sleepiness, or affect vision, so driving or operating machinery should be avoided until its effects are known.
Please consult yor doctor before taking Esoral 20 with alcohol.
Using Esoral 20 during pregnancy may pose potential risks. While human studies on this matter are limited, animal studies have demonstrated adverse effects on the growth and development of the fetus. Please consult your doctor before taking Esoral 20.
The safety of using Esoral 20 during breastfeeding is questionable. Although there is limited human data available, it suggests that the drug may enter the breastmilk and potentially harm the nursing infant.
The impact of Esoral 20 on driving ability is uncertain. If you experience any symptoms that affect your concentration and reaction time, it is advised not to drive.
Esoral 20 is safe to use in patients with kidney disease. However, inform your doctor if you have any kidney disease.
Esoral 20 should be used with caution in patients with severe liver disease. Please consult your doctor.
When compared to short-term treatment, there is no difference in the categories of linked adverse events noticed with maintenance treatment up to 12 months.
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esoral 20 is to be taken empty stomach.
Esoral 20 is a medication that lessens the quantity of acid your stomach produces. Heartburn, acid reflux, and issues with your food pipe are all treated with it. Stomach ulcers can also be prevented and treated with them. Esoral 20 should be taken as prescribed by your doctor.
The H+/K+ ATPase in the gastric parietal cell is inhibited by the proton pump inhibitor esomeprazole, which reduces the amount of stomach acid produced. Esomeprazole (omeprazole's S-isomer), the first proton pump inhibitor with a single optical isomer, offers better acid control than racemic proton pump inhibitors.
Erosive esophagitis-
Maintenance of healing of erosive esophagitis-
Risk reduction in NSAID-associated gastric ulcer-
H. pylori eradication (Esomeprazole MUPS tablet with 1000 mg Amoxicillin and 500 mg Clarithromycin)-
Zollinger-Ellison syndrome and idiopathic hypersecretion-
Children 1-11 years:
Erosive esophagitis: Weight <20 kg: 10 mg once daily for 8 weeks. Weight ≥20 kg: 10 mg or 20 mg once daily for 8 weeks
Maintenance of healing of erosive esophagitis: 10 mg once daily
Children below the age of 1 year: Esomeprazole Mups tablet is not approved for use in children younger than 1 year.
Esomeprazole tablet or capsule: should be swallowed whole and taken one hour before a meal.
Delayed-Release Oral Suspension uses guidelines: The entire packet's contents should be placed in a little glass with 15 ml of water. After thoroughly stirring the mixer, give it two to three minutes to thicken. Within 30 minutes, stir once more and consume. Add extra water, swirl, and drink right away if any medicine is still present after consumption. If the suspension is to be taken via a nasogastric or gastric tube, 15 ml of water should be placed in the syringe. After shaking the syringe, wait two to three minutes for the suspension to thicken. Within 30 minutes, shake the syringe and inject it into the stomach using a nasogastric or gastric tube. Make sure to use a syringe that is the right size. Shake and ingest any leftover substances through the gastric or nasogastric tube.
Esomeprazole IV Injection: Esomeprazole IV needs to be injected slowly into the vein. The solution for IV injection is made by adding 5 ml of the supplied solvent (WFI) to the vial. The injection should be administered carefully over a minimum of three minutes following reconstitution. If the solution is kept at room temperature up to 30°C, it needs to be used within 12 hours of reconstitution. There is no need for refrigeration. If the reconstituted solution has visible particles, don't use it.
Esoral 20 usage over an extended period of time may result in weak bones and a mineral deficit, especially magnesium. Consume enough calcium and magnesium in your diet or take supplements as directed by your doctor.
If you experience decreased urine, edema (swelling brought on by fluid retention), lower back discomfort, nausea, exhaustion, rash, or fever, call your doctor immediately once. These might be kidney-related symptoms.
Esomeprazole is metabolized by CYP2C19 and CYP3A4 in the liver, and does not significantly inhibit other CYP enzymes. However, it may interfere with the absorption of drugs affected by gastrointestinal pH, such as ketoconazole, iron salts, and digoxin.
Oral contraceptives, diazepam, phenytoin, or quinidine do not affect Esomeprazole's pharmacokinetics. When combined with clarithromycin and amoxicillin, the plasma levels of esomeprazole and 14-hydroxyclarithromycin increase.
Esomeprazole is contraindicated in patients with known hypersensitivity to any of the formulations.
The manufacturer advises caution. It is not known if Esomeprazole or its metabolites appear in human breast milk.
If the patient has severe liver failure and renal impairment, esomeprazole should be administered with caution. Proton pump inhibitors, such as Esomeprazole, may marginally increase the risk of hip, wrist, and spine fractures, especially when used for more than a year.
Store in a cool & dry place below 25ºC, and protect from light. Keep out of reach of children.
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