Dexend 60mg 10pcs
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Dexend 60mg 10pcs

Type: Capsule

Pack Size: 10 Pcs

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Discount Price: ৳ 152
MRP: ৳ 160 5% Off

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✅ Description:

Indications of Dexend Capsule

Healing of erosive esophagitis: Dexlansoprazole is suitable for the treatment of all grades of erosive esophagitis (EE) for up to 8 weeks.

Maintenance of healing of erosive esophagitis: Dexlansoprazole is used to maintain healing of EE and relieve heartburn for up to 6 months.

Symptomatic non-erosive gastroesophageal reflux disease: Dexlansoprazole is indicated for the treatment of heartburn associated with symptomatic non-erosive gastroesophageal reflux disease (GERD) for a period of 4 weeks.

 

Pharmacology of Dexend Capsule

Dexlansoprazole sustained-release capsule is a proton pump inhibitor (PPI), which inhibits gastric acid secretion by specifically inhibiting (H + / K +) ATPase in gastric parietal cells. By acting exclusively on the proton pump, dexlansoprazole prevents the last step of acid production. It is the enantiomer of lansoprazole (a racemic mixture of R and the enantiomer). Dexlansoprazole is provided as a dual delayed release (DDR) formulation in an oral capsule. The capsule contains a mixture of two types of enteric-coated granules, which have different pH-dependent dissolution profiles. The dual delayed-release formulation in dexlansoprazole has two different peak plasma concentration time profiles; the first peak appears 1 to 2 hours after administration, followed by the second peak within 4 to 5 hours. After oral administration, the mean Cmax and AUC values ​​of dexlansoprazole increase approximately in proportion to the dose. Dexlansoprazole is extensively metabolized in the liver and excreted in the urine.

 

Dexend Capsule Dosage & Administration

Dexlansoprazole dosing recommendations-

Maintenance of Healed erosive esophagitis and relief of heartburn: 30 mg Once daily

Symptomatic Non-Erosive GERD: 30 mg Once daily for 4 weeks

Healing of erosive esophagitis: 60 mg Once daily for up to 8 weeks

Dexlansoprazole can be taken without regard to food. It should be swallowed whole.

Alternatively, Dexlansoprazole capsules can be administered as follows:

Open capsule

Sprinkle intact granules on one tablespoon

Swallow immediately.

Granules should not be chewed.

If a capsule is missed at its usual time, it should be taken as soon as possible. But if it is too close to the time of the next dose, only the prescribed dose should be taken at the appointed time. A double dose should not be taken.

 

Interactions

Drugs used: atazanavir, warfarin, tacrolimus, clopidogrel and methotrexate. With food and others: no data available.

 

Contraindications

Patients who are known to be allergic to any component of the preparation should not use dexlansoprazole.

 

Side Effects

Common side effects: diarrhea, abdominal pain, nausea, vomiting and flatulence.

 

Pregnancy

Pregnancy category B. There are no adequate and well-controlled studies on the use of dexlansoprazole in pregnant women. There are no adequate and well-controlled studies on the use of dexlansoprazole in breastfeeding mothers.

 

Precautions

Gastric neoplasms, Clostridium difficile-related diarrhea, fractures, hypomagnesemia, and simultaneous use of dexlansoprazole and methotrexate.

Storage Conditions

Store below 30°C temperature & in a dry place, protected from light. Keep all medicines out of reach of children.

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Check our pricing section for Dexend 60mg 10pcs price in Bangladesh. After Submitting Order, You may receive phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

📦Pricing Information, Availability:
Product Availability & Pricing Notice Please note that pricing, availability, and service offerings are subject to change due to: Market fluctuations, Manufacturer or supplier adjustments, Product discontinuation or temporary unavailability, Advertising errors. All orders depend on stock availability and staff resources. If services are provided on a time-and-materials basis, any shared estimates are for planning purposes only.

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