Itra 100mg Capsule

Uses of Itra 100mg Capsule

• Treatment of Fungal Infections

How does Itra 100mg Capsule work?

Itra 100mg Capsule works by preventing fungal growth by blocking the production of enzymes responsible for the growth of fungal cells. This inhibition results in the breakage of cell membranes and fungal cell abnormalities, finally leading to alterations in the membrane-based activity of fungus. These lead to fungal cell death and prevention of further fungal growth. 

Side Effects of Itra 100mg Capsule

• Tiredness
• Cough
• Cold
• Throat pain
• Back pain
• Stomach pain
• Increased frequency of urine
• Blurred or double vision
• Taste changes
• Blood disorders increase the risk of infections
• Ringing in ears
• Hearing loss (may be permanent)
• Swelling due to fluid under the skin, hair loss
• Redness, itching, flaking, or peeling skin
• Sensitivity of the skin to light
• Erection problems

Quick Suggestions:

• When taking Itra 100, be sure to finish the full course of treatment, take it with food at the same time each day, and use reliable contraception.
• Avoid taking antacids within two hours of taking Itra 100.
• Your doctor may check your liver function and you should inform them if you experience yellowing of the eyes or skin, dark urine, or stomach pain.
• Be sure to notify your doctor if you develop allergic reactions, nerve pain, or hearing loss while taking Itra 100.

Here are some tips to prevent fungal infections: 

1. keep your feet clean and dry, avoid wearing shoes that cause your feet to sweat, and don't walk barefoot in public places.
2. Avoid sharing personal items such as towels, combs, and shoes, and regularly wash your bedding and towels.

Indication of Itra 100mg Capsule

Blastomycosis, Histoplasmosis, Invasive Aspergillosis, Onychomycosis, Vulvovaginal Candidiasis, Pityriasis Versicolor, Dermatophytoses, and Oral candidiasis are different fungal infections that can affect various parts of the body, including lungs, skin, bones, joints, and mouth. Itra 100mg Capsule is an effective medication that slows down the growth and spread of fungi, thus helping to treat these conditions. The symptoms of these infections may include weight loss, night sweats, fever, cough, chest pain, tiredness, itching, rashes, and white lesions on the tongue and inner cheeks. It is important to complete the full course of treatment and to inform your doctor if you experience any adverse reactions such as allergic reactions, nerve pain, hearing loss, or yellowing of the eyes or skin.

Pharmacology

Itraconazole is an orally administered triazole antifungal medication with a broad spectrum of action and a favorable pharmacokinetic profile. Itraconazole inhibits Cytochrome P-450-dependent enzymes, impairing the formation of ergosterol, a significant component of yeast and fungal cell membranes. Because ergosterol is essential for the proper functioning of the cell membrane, inhibiting its synthesis causes a cascade of abnormalities in permeability, membrane-bound enzyme activity, and chitin synthesis coordination, resulting in growth inhibition, abnormal cell wall formation, and the accumulation of intracellular lipids and membranous vesicles.

Dosage & Administration of Itra 100mg Capsule

• Itraconazole dosage varies based on the type of fungal infection being treated. For oropharyngeal candidiasis, the recommended dosage is 100 mg daily for 15 days (or 200 mg daily in individuals with AIDS or neutropenia). For vulvovaginal candidiasis, the recommended dosage is 200 mg twice daily for one day. For pityriasis versicolor, the recommended dosage is 200 mg daily for 7 days. For tinea corporis and tinea cruris, the recommended dosage is either 100 mg daily for 15 days or 200 mg daily for 7 days. For tinea pedis and tinea manuum, the recommended dosage is either 100 mg daily for 30 days or 200 mg twice daily for 7 days.
• For onychomycosis, the recommended dosage is either 200 mg daily for 3 months or a pulse course of 200 mg twice daily for 7 days with subsequent courses repeated after a 21-day interval. For fingernails, two courses are recommended and for toenails, three courses are recommended. For systemic infections such as aspergillosis, candidiasis, and cryptococcosis, including cryptococcal meningitis, where other antifungal drugs are ineffective, the recommended dosage is 200 mg once daily and may be increased in invasive or disseminated disease and in cryptococcal meningitis to 200 mg twice daily.
• For histoplasmosis, the recommended dosage is 200 mg once or twice daily. In AIDS patients, it is used for maintenance to prevent relapse of underlying fungal infections, and in neutropenia when standard therapy is inappropriate, the recommended dosage is 200 mg once daily, which may be increased to 200 mg twice daily if low plasma itraconazole concentration is detected. For children, the recommended dose is 3 to 5 mg/kg/day.

Take Itra 100mg Capsule as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your doctor will decide the correct dose and duration of Itra 100mg Capsule for you depending upon your age, body weight, and disease condition.

Interaction

Itra 100mg Capsule has several potential drug interactions that you should be aware of. It may interact with antacids, corticosteroids, opioid painkillers, blood thinners, blood cholesterol-lowering medicines, anti-allergic drugs, and antianxiety drugs. If you are taking any of these medications, inform your doctor before starting Itra 100mg Capsule.

Itra 100mg Capsule may also interact with grapefruit juice, which can reduce its effectiveness. Therefore, it is recommended to avoid intake of grapefruit juice while taking this medication. Additionally, intake of marijuana with Itra 100mg Capsule may worsen the adverse effects of marijuana.

If you have a history of heart failure, you should not take Itra 100mg of Capsule as it may cause severe life-threatening adverse effects. If you have kidney, liver, heart, or lung problems, you should inform your doctor before taking Itra 100mg Capsules. It is important to discuss all your medical conditions and medications with your doctor before starting this medication to avoid any potential drug-disease interactions.

Contraindications

Itraconazole is contraindicated in patients with known hypersensitivity to the drug or any ingredient in the formulation, Patients who have severe hepatic disease are not advised to take itraconazole. it is not advisable to use the drug in patients taking rifampin, which appears to initially inhibit and then enhance the metabolism of itraconazole.

Pregnancy & Lactation

Itraconazole is contraindicated in pregnancy. Breastfeeding while receiving Itraconazole is not recommended.

Precaution & Warnings

• It is important to follow the dosage and duration of treatment recommended by your doctor when taking Itra 100mg Capsule.
• Do not stop taking the medicine without consulting your doctor, even if you start feeling better, as this may lead to the recurrence of the infection.
• If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular dosing schedule. Do not take a double dose to make up for the missed one.
• Itra 100mg Capsule may cause some side effects, such as headache, dizziness, stomach upset, diarrhea, nausea, and vomiting. These side effects are usually mild and go away on their own. However, if you experience any severe or persistent side effects, such as difficulty breathing, chest pain, irregular heartbeat, or swelling of the face, lips, tongue, or throat, seek immediate medical attention.
• In summary, it is important to inform your doctor of any allergies, medical conditions, or other medications you are taking before using Itra 100mg Capsule.
• Follow the recommended dosage and duration of treatment, and report any side effects or unusual symptoms to your doctor promptly.
• Regular blood tests are recommended before and while taking Itra 100mg Capsule to monitor liver functioning especially if you have any liver problems.

Storage Conditions

Keep away from light and heat in a dry area. Keep out of children's reach.