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Clarizol is indicated for the treatment of:
- Dermatomycoses are caused by dermatophytes (e.g., Trichophyton species).
- Fungal skin infections caused by yeasts (Candida species).
- Dermatomycoses due to molds and other fungi.
- Skin conditions complicated by fungal superinfections.
Examples include:- Interdigital mycoses (e.g., athlete's foot).
- Paronychias (associated with nail infections).
- Skin fold infections.
- Candida vulvitis and balanitis.
- Pityriasis versicolor.
- Erythrasma.
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✅ Description:
Clarizol is a broad-spectrum antifungal medication effective against dermatophytes, yeasts, moulds, and some gram-positive bacteria, such as Staphylococci and Trichomonas. It works by altering fungal cell membrane permeability, primarily by inhibiting ergosterol synthesis. At higher concentrations, it also damages the fungal membrane, disrupting growth.
Beyond antifungal activity, clotrimazole impacts intracellular calcium levels by inhibiting sarcoplasmic reticulum Ca²⁺ ATPase, blocking calcium-dependent potassium channels, and voltage-dependent calcium channels.
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✔️ Dosage & Administration: Clotrimazole Cream
Clotrimazole Cream:
- Apply a thin layer 2-3 times daily to the affected areas and gently rub in.
- A small amount is sufficient for an area the size of a palm.
- Consistent and prolonged application is essential for effective treatment.
✔️ Recommended Duration: Clotrimazole Cream
- Dermatomycoses: 3-4 weeks.
- Candida vulvitis and balanitis: 1-2 weeks.
- Erythrasma and Pityriasis versicolor: Approximately 3 weeks.
- For foot infections, continue treatment for 2 weeks after symptoms clear to prevent relapse.
✔️ Interactions
No significant drug interaction data is available.
✔️ Contraindications
- Hypersensitivity to clotrimazole.
✔️ Side Effects
- Generally well-tolerated when used topically.
- Rare cases of local irritation or burning sensation may occur but are not harmful.
✔️ Pregnancy & Lactation
- Use during pregnancy only if deemed necessary by a doctor.
✔️ Storage Conditions
- Store below 25°C, away from light and moisture.
- Keep out of reach of children.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
