Esoral 20mg 14pcs

Uses of Esoral 20:

• Treatment of Gastroesophageal reflux disease (Acid reflux)
• Treatment of Peptic ulcer disease

SIde Effects of Esoral 20:

When compared to short-term treatment, there is no difference in the categories of linked adverse events noticed with maintenance treatment up to 12 months.

• Headache
• Dizziness
• Dryness in mouth
• Nausea
• Abdominal pain
• Constipation
• Flatulence
• Diarrhea are the most common side effect reported with Esomeprazole.

How to use Esoral 20:

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Esoral 20 is to be taken empty stomach.

Quick Suggestions of Esoral 20:

• Esoral 20 is a medication that reduces stomach acid production.
• It is used to treat heartburn, acid reflux, and stomach ulcers.
• The dose should be the lowest effective amount for the shortest duration necessary.
• It should be taken an hour before meals and at the same time each day.
• It may take a few weeks to work effectively, but the doctor will advise on the duration of treatment.
• Common side effects include headache, constipation, and stomach pain.
• Serious side effects are rare but require immediate medical attention.

Indication of Esoral 20:

Esoral 20 is a medication that lessens the quantity of acid your stomach produces. Heartburn, acid reflux, and issues with your food pipe are all treated with it. Stomach ulcers can also be prevented and treated with them. Esoral 20 should be taken as prescribed by your doctor.

Pharmacology of Esoral 20:

The H+/K+ ATPase in the gastric parietal cell is inhibited by the proton pump inhibitor esomeprazole, which reduces the amount of stomach acid produced. Esomeprazole (omeprazole's S-isomer), the first proton pump inhibitor with a single optical isomer, offers better acid control than racemic proton pump inhibitors.

Dosage & Administrations of Esoral 20:

Erosive esophagitis-

• Adult (≥18 years): 40 mg once daily for 4 weeks.
• Children & adolescents (12-18 years): 40 mg once daily for 4 weeks.

Maintenance of healing of erosive esophagitis-

• Adult (≥18 years): 20 mg once daily.
• Children & adolescents (12-18 years): 20 mg once daily.

Risk reduction in NSAID-associated gastric ulcer-

• Adult (≥18 years): 20 mg once daily for 4-8 weeks.

H. pylori eradication (Esomeprazole MUPS tablet with 1000 mg Amoxicillin and 500 mg Clarithromycin)-

• Adult (≥18 years): 20 mg twice daily for 7 days.
• Children & adolescents (12-18 years): 20 mg twice daily for 7 days.

Zollinger-Ellison syndrome and idiopathic hypersecretion-

• Adult (≥18 years): 40-80 mg twice daily.

Children 1-11 years:

Erosive esophagitis: Weight <20 kg: 10 mg once daily for 8 weeks. Weight ≥20 kg: 10 mg or 20 mg once daily for 8 weeks

Maintenance of healing of erosive esophagitis: 10 mg once daily

Children below the age of 1 year: Esomeprazole Mups tablet is not approved for use in children younger than 1 year.

Esomeprazole tablet or capsule: should be swallowed whole and taken one hour before a meal.

Delayed-Release Oral Suspension uses guidelines: The entire packet's contents should be placed in a little glass with 15 ml of water. After thoroughly stirring the mixer, give it two to three minutes to thicken. Within 30 minutes, stir once more and consume. Add extra water, swirl, and drink right away if any medicine is still present after consumption. If the suspension is to be taken via a nasogastric or gastric tube, 15 ml of water should be placed in the syringe. After shaking the syringe, wait two to three minutes for the suspension to thicken. Within 30 minutes, shake the syringe and inject it into the stomach using a nasogastric or gastric tube. Make sure to use a syringe that is the right size. Shake and ingest any leftover substances through the gastric or nasogastric tube.

Esomeprazole IV Injection: Esomeprazole IV needs to be injected slowly into the vein. The solution for IV injection is made by adding 5 ml of the supplied solvent (WFI) to the vial. The injection should be administered carefully over a minimum of three minutes following reconstitution. If the solution is kept at room temperature up to 30°C, it needs to be used within 12 hours of reconstitution. There is no need for refrigeration. If the reconstituted solution has visible particles, don't use it.

Esoral 20 usage over an extended period of time may result in weak bones and a mineral deficit, especially magnesium. Consume enough calcium and magnesium in your diet or take supplements as directed by your doctor.
If you experience decreased urine, edema (swelling brought on by fluid retention), lower back discomfort, nausea, exhaustion, rash, or fever, call your doctor immediately once. These might be kidney-related symptoms.

Interaction of Esoral 20:

Esomeprazole is metabolized by CYP2C19 and CYP3A4 in the liver, and does not significantly inhibit other CYP enzymes. However, it may interfere with the absorption of drugs affected by gastrointestinal pH, such as ketoconazole, iron salts, and digoxin.

Oral contraceptives, diazepam, phenytoin, or quinidine do not affect Esomeprazole's pharmacokinetics. When combined with clarithromycin and amoxicillin, the plasma levels of esomeprazole and 14-hydroxyclarithromycin increase.

Contraindications of Esoral 20:

Esomeprazole is contraindicated in patients with known hypersensitivity to any of the formulations.

Pregnancy & Lactation:

The manufacturer advises caution. It is not known if Esomeprazole or its metabolites appear in human breast milk.

Precautions & Warnings of Esoral 20:

If the patient has severe liver failure and renal impairment, esomeprazole should be administered with caution. Proton pump inhibitors, such as Esomeprazole, may marginally increase the risk of hip, wrist, and spine fractures, especially when used for more than a year.

Storage Conditions of Esoral 20:

Store in a cool & dry place below 25ºC, and protect from light. Keep out of reach of children.