Intravas 60mg Injection | 0.6ml | Anticoagulant Medicine | ePharma
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Intravas 60mg Injection

Generic: Enoxaparin Sodium

Type: Injection

Pack Size: 1 Pc

  • Enoxaparin is an anticoagulant medicine that is used to prevent blood clots in the legs.
  • It is used in combination with warfarin to treat blood clots.
  • This medicine works by inactivating the clotting factors that are responsible for blood clotting.
  • It is not recommended for use in children under 18 years of age.

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Discount Price: ৳ 564
MRP: ৳ 600 6% Off

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✅ Description:

Intravas 60mg Injection (Generic Name: Enoxaparin) is an anticoagulant medication that helps prevent the formation of blood clots. It is commonly used in the prevention of deep vein thrombosis (DVT) after certain surgeries, such as hip or knee replacements and abdominal surgeries, where the risk of thromboembolic complications is higher. Additionally, it is used for the inpatient and outpatient treatment of acute DVT, both with and without pulmonary embolism, when administered in conjunction with warfarin sodium.

The drug can also be used to prevent ischemic complications of unstable angina and non-Q wave myocardial infarction when given alongside aspirin.

Enoxaparin is available in injection form, and it is typically administered to patients who are recuperating at home after surgery or are at risk for blood clots due to certain medical conditions. The dosage of Intravas 60mg Injection is determined based on factors such as age, overall health, and the body's response to the initial dose.

While using Intravas 60mg Injection, it's important to be cautious about potential side effects, including bruising and pain at the injection site. It may also cause a tendency to bleed easily, and certain precautions should be taken, such as using a soft toothbrush, waxed floss for dental care, and electric razors for shaving. Avoiding sharp objects and potentially harmful activities can reduce the risk of injuries.

If any concerning symptoms occur, such as chest pain, persistent constipation, persistent erection, unusual bleeding or bruising, joint or back pain, numbness, tingling, swelling, or pain at the injection site, it's crucial to report them to a healthcare professional promptly.

Overdosing on Intravas 60mg Injection may lead to hemorrhage, and in such cases, the effects can be reversed with the use of protamine sulfate.

Always follow the prescribed dosage and do not stop taking the medication abruptly, as this can increase the risk of developing blood clots. If you have any questions or concerns about using Intravas 60mg Injection, it's essential to consult a Hematologist or another qualified healthcare provider for personalized guidance.

Safety Advices


Alcohol
UNSAFE

Avoid consumption of alcohol before receiving  Intravas 60mg Injection.


Pregnancy
CONSULT YOUR DOCTOR

Intravas 60mg Injection is not recommended for use in pregnancy. Your doctor will weigh the benefits and risks before prescribing this medicine to you.


Breastfeeding
CONSULT YOUR DOCTOR

Intravas 60mg Injection is not recommended for use in breastfeeding. Your doctor will weigh the benefits and risks before prescribing this medicine to you.


Driving
CAUTION

Intravas 60mg Injection does not affect your ability to drive or operate machinery. However, do not drive or handle any heavy tools or machines if your ability is affected by  Intravas 40mg Injection.


Kidney
CONSULT YOUR DOCTOR

Intravas 60mg Injection may increase the risk of bleeding if you have kidney problems. Your doctor may adjust the dose of this medicine or prescribe a suitable alternative based on your condition.


Liver
CONSULT YOUR DOCTOR

Intravas 60mg Injection is known to increase the levels of liver enzymes causing serious complications. Therefore, it should be used with caution if you have liver problems.

Similar Products

✔️ Uses of Intravas 60mg Injection
  • Prophylaxis For Deep Vein Thrombosis
  • Prophylaxis For Angina And Myocardial Infarction
  • Deep Vein Thrombosis Prophylaxis After Surgery
✔️ How does Intravas 60mg Injection work?

Intravas 60mg Injection has enoxaparin as its main ingredient. Enoxaparin is an anticoagulant medication. It works as an anticoagulant and helps in preventing blood clots.

✔️ Side Effects of Intravas 60mg Injection

COMMON side effects:

  • Bleeding and bruising - As an anticoagulant, Intravas 60mg injection can increase the risk of bleeding and bruising.
  • Injection site reactions - Some people may experience pain or redness at the site of injection.
  • Pinky patches on the skin - Skin discoloration, especially at the injection site, may occur.
  • Skin rash, itching, redness - Allergic reactions to the medication can lead to skin-related symptoms.
  • Low red blood cell count - Intravas 60mg Injection may cause a decrease in red blood cells, leading to anemia.
  • Headache - Headaches may occur as a general side effect of the medication.

UNCOMMON side effects:

  • Sudden severe headache - This can be a sign of a more serious condition and requires immediate medical attention.
  • Tender and swollen stomach - Abdominal pain and swelling may occur in some cases.

RARE side effects:

  • Increased blood potassium levels - Elevated potassium levels can have various effects on the body.
  • Hair loss - Some individuals may experience hair loss as a rare side effect.
  • Osteoporosis - Long-term use of certain anticoagulants, including Intravas 60mg Injection, may contribute to bone weakening and osteoporosis.
  • Tingling, numbness, and muscular weakness - These symptoms, especially in the lower part of the body, may occur after a spinal puncture or spinal anesthetic in combination with Intravas 60mg Injection use.
  • Loss of control over the intestine or bladder - In rare cases, Intravas 60mg Injection may lead to loss of bladder or bowel control.

It is important to note that the occurrence of these side effects may vary from person to person. If you experience any of these side effects or other concerning symptoms while using Intravas 60mg Injection, it is crucial to seek medical advice from a healthcare professional promptly. They can assess the situation and provide appropriate guidance or adjustments to your treatment plan.

✔️ Quick Suggestions:
  • Intravas 60mg Injection is a type of anticoagulant medication. It is used to treat blood clot disorders such as deep vein thrombosis and pulmonary embolism by preventing the formation of blood clots.
  • It is also used to prevent blood clots from forming in your blood during and after surgery, in bedridden patients, after a heart attack, or due to angina and to prevent clots from forming in dialysis.
  • Maintaining a healthy and active lifestyle can help prevent the formation of blood clots. While taking this medication, you may experience a tendency to bleed easily.
  • Be cautious when shaving, using sharp objects, or cutting fingernails or toenails.
  • Inform your doctor if you are also taking any other medications that increase the risk of bleeding, such as aspirin or NSAIDs.
  • Do not stop taking the medication abruptly without first consulting your doctor.
✔️ Indication of Intravas 60mg Injection

Enoxaparin is indicated for:

  • Treatment of deep vein thrombosis, with or without pulmonary embolism.
  • Treatment of unstable angina and non-Q-wave myocardial infarction, administered concurrently with aspirin
  • Prevention of thrombus formation in the extra-corporal circulation during hemodialysis.
  • Prophylaxis of venous thromboembolic disease (prevention of blood clot formation in the veins), in particular those which may be associated with orthopedic or general surgery.
  • Prophylaxis of venous thromboembolic disease in medical patients bedridden due to acute illness, including cardiac insufficiency, respiratory failure, severe infections, and rheumatic diseases.
✔️ Pharmacology

It is a low molecular weight heparin with a higher anti-Xa activity compared to its anti-IIa or antithrombin activity. This means that its primary mode of action is to inhibit Factor Xa, a key factor in the blood clotting cascade, and it has a lower effect on inhibiting Factor IIa (thrombin) or antithrombin.

At the dosages used for different medical indications, Enoxaparin Sodium does not significantly increase bleeding time, meaning it does not have a major impact on the time it takes for blood to clot. This characteristic is crucial for its safety and efficacy in preventing and treating thromboembolic conditions.

At preventive doses, Enoxaparin Sodium does not cause a significant alteration of the activated Partial Thromboplastin Time (aPTT), which is a common laboratory test used to assess coagulation status.

It's important to note that Enoxaparin Sodium does not affect platelet aggregation (clumping) or the binding of fibrinogen to platelets. This property sets it apart from other anticoagulants that may interfere with platelet function.

Regarding metabolism, Enoxaparin Sodium is primarily metabolized in the liver. This hepatic metabolism contributes to its elimination from the body.

Overall, Enoxaparin Sodium's pharmacological properties make it a commonly used and effective anticoagulant for preventing and treating various thromboembolic disorders. However, as with any medication, it should be used under the supervision and guidance of a healthcare professional to ensure appropriate dosing and monitoring.

✔️ Dosage & Administration of

Adult Dose:

Deep Vein Thrombosis (Prophylaxis):

  • Abdominal surgery: 40 mg SC once daily, initiated 2 hours before the surgery.
  • Knee or hip replacement surgery: 30 mg SC every 12 hours, initiated 12-24 hours postoperatively and continued for 10 days or up to 35 days postoperatively, or until the risk of DVT has significantly reduced, or the patient is on anticoagulant therapy.
  • Medical patients with restricted mobility: 40 mg SC once daily; continue until the risk of DVT has significantly reduced (6-11 days) or the patient is on anticoagulant therapy.

Deep Vein Thrombosis (Treatment):

  • Inpatient treatment (with or without pulmonary embolism) when coadministered with warfarin sodium: 1 mg/kg SC every 12 hours or 1.5 mg/kg SC once daily (administer at the same time each day).
  • Outpatient treatment (without pulmonary embolism) when coadministered with warfarin sodium: 1 mg/kg SC every 12 hours.

Unstable Angina & Non-Q-Wave MI:

  • Prophylaxis of ischemic complications when concurrently administered with aspirin: 1 mg/kg SC every 12 hours.

Acute ST-Segment Elevation Myocardial Infarction (STEMI):

  • Loading dose: 30 mg IV bolus once, plus 1 mg/kg SC once (not to exceed 100 mg cumulative loading dose).
  • Maintenance dose for patients <75 years: 1 mg/kg SC every 12 hours.
  • Maintenance dose for patients >75 years: 0.75 mg/kg SC every 12 hours (no initial IV bolus).

Renal Dose:

  • In patients with severe renal impairment (CrCl <30 mL/min), dosage reductions are required for all indications. The reduced dosage is 30 mg SC once daily for prophylaxis in abdominal surgery, hip or knee replacement surgery, and medical patients with restricted mobility.

Administration:

  • Intravas 60mg Injection is administered as a deep subcutaneous injection (SC) into the skin fold held between the thumb and forefinger, alternating between the right and left anterior and posterior abdominal walls.
  • For intravenous (IV) administration, it can be given in an IV line with 0.9% NaCl (normal saline) or D5W (5% dextrose in water).

It is essential to follow the prescribed dosage and administration instructions given by a healthcare professional. If you have any concerns or questions about your treatment with Intravas 60mg Injection, consult your doctor or pharmacist for personalized advice.

✔️ Interaction

It's crucial for patients to inform their healthcare provider about all the medications, supplements, and herbal preparations they are taking before starting Intravas 60mg Injection. Some medications may interact with Intravas 60mg Injection, affecting its effectiveness or increasing the risk of side effects.

Certain medicines should be used with caution or require careful monitoring when used alongside Intravas 60mg Injection. These include:

  1. Escitalopram: An antidepressant medication.
  2. Warfarin: Another anticoagulant drug used to prevent blood clots.
  3. Aspirin: A common antiplatelet medication used to prevent blood clots.
  4. Roxifiban, tirofiban, and eptifibatide: Antiplatelet drugs used to prevent platelet aggregation and blood clot formation.
  5. Clopidogrel and ticlopidine: More antiplatelet medications.

Also, the use of nonsteroidal anti-inflammatory drugs (NSAIDs) like ibuprofen should be approached with caution when using Intravas 60mg Injection, as they can increase the risk of bleeding.

✔️ Contraindications
  • Hypersensitivity
  • Thrombocytopenia
  • Bleeding Disorders
✔️ Pregnancy & Lactation

Pregnancy category B. In people, there's no proof that Enoxaparin Sodium crosses the placental obstruction. As there are no satisfactory and well-controlled things about pregnant ladies, Enoxaparin Sodium ought to be utilized amid pregnancy as it were in the case clearly required. Pregnant ladies with mechanical prosthetic heart valves may be at the next hazard for thromboembolism. It isn't known whether Enoxaparin is excreted in human milk. Since numerous drugs are excreted in the human drain as a result of the potential for genuine unfavorable responses in nursing newborn children, a choice ought to be made whether to cease nursing or suspend Enoxaparin, taking into consideration the significance of Enoxaparin to the mother and the known benefits of nursing.

✔️ Precautions & Warnings
  • Bleeding: Intravas 60mg Injection can cause severe bleeding, and it is not recommended for individuals with a history of gastrointestinal bleeding or head injury. It should be used with caution in patients about to undergo surgery. Any signs of bleeding, such as blood in stools, vomiting blood, or blood in urine, should be reported to the doctor immediately. Blood tests, like prothrombin time monitoring, may be required to assess clot formation.
  • Liver Disease: Intravas 60mg Injection can increase liver enzyme levels, potentially leading to serious complications. Use caution if you have liver problems.
  • Kidney Diseases: Patients with kidney problems may have an increased risk of bleeding when using Intravas 60mg Injection. The doctor may adjust the dosage or prescribe an alternative medication based on the patient's condition.
  • Percutaneous Coronary Revascularization Procedures: Intravas 60mg Injection should be used cautiously in patients who have undergone procedures like percutaneous coronary revascularization for unstable angina or myocardial infarction to minimize the risk of bleeding.
  • Heparin-Induced Thrombocytopenia: If the patient has a history of heparin-induced thrombocytopenia, Intravas 60mg Injection should be used with caution, and treatment may be stopped if the platelet levels drop below a certain threshold.
  • Administration Route: Enoxaparin Sodium should be administered by deep subcutaneous injection for both prophylactic and therapeutic use and should not be given intramuscularly.
  • Increased Bleeding Risk: Intravas 60mg Injection should be used with caution in conditions with an increased potential for bleeding, such as impaired hemostasis (blood clotting), history of peptic ulcer, recent ischemic stroke, uncontrolled severe arterial hypertension, diabetic retinopathy, recent neuro- or ophthalmologic surgery, and concurrent use of medications affecting hemostasis.
  • Platelet Counts: Before starting treatment and during the course of therapy, platelet counts should be measured regularly.
✔️ Storage Conditions

Store Intravas 60mg Injection under the conditions mentioned on the pack. Keep it away from children and pets.

Frequently Asked Questions (FAQ)

This drug is used to treat clotting of blood.

Store Intravas 60mg Injection at room temperature, preferably around 25°C (77°F), and avoid freezing the medication. Multiple-dose vials should not be kept for more than 28 days after the first use to maintain its potency and safety. Before using this medication, it is essential to read the medicine package leaflet thoroughly. If you have any doubts or questions about its usage, consult your pharmacist for clarification and guidance.

Intravas 60mg Injection is administered as a subcutaneous injection. Follow the prescribed dose of the medicine as instructed by your doctor. To administer the injection, follow these steps: Pinch the skin of your stomach between your finger and thumb to create a fold. Clean the injection site area with an alcohol swab or as directed by your doctor. Hold the syringe like a pencil and insert the full length of the needle into the skin fold at a 45 to 90-degree angle. Inject the medicine slowly and steadily. After the injection, dispose of the syringe as instructed by your prescribing physician. Follow all the instructions given by your doctor strictly, and in case of any doubts or reactions associated with the medicine, contact your doctor immediately.

Yes, this Intravas 60mg Injection is given based on your age and body weight. If you have low body weight, the chances of increased risk of bleeding are high, so mostly low doses are prescribed by your doctor. You may be monitored closely for signs of clot formation.

Intravas 60mg Injection is used to treat chest pain and heart attacks in combination with standard treatment. It is administered alongside another blood thinner, typically aspirin. As a blood-thinning agent, Intravas 60mg Injectio prevents blood clot formation, reducing the risk of further episodes and complications.
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ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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