Generic Name: Salbutamol 100mcg
Manufacturer/Distributor: Square Pharmaceuticals Ltd.
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Indications
Salbutamol Inhaler is used to treat or prevent bronchospasm in individuals with bronchial asthma as well as reversible airway obstruction in individuals with bronchitis and emphysema.
Exercise-Induced Bronchospasm: Salbutamol Inhaler can be used to treat acute dyspnea and prevent exercise-induced asthma or as a preventative measure before exercising.
Pharmacology
The 2-adrenoceptor is a selective agonist of salbutamol. It has therapeutic effects on the 1-adrenoceptors of cardiac muscle but little to no effect on the 2-adrenoceptors of bronchial smooth muscle. Salbutamol causes short-acting (4-6 hours) bronchodilation with a rapid onset in reversible airway obstruction (within 5 minutes). By acting as an anti-inflammatory on mast cells, it also prevents the release of bronchoconstrictor mediators like histamine, neutrophil chemotactic factor (NCF), and prostaglandin D2.
Dosage
For relief of acute episodes of bronchospasm:
To prevent allergen-or exercise-induced bronchospasm:
Chronic therapy:
Administration
Interaction
Salbutamol and non-selective beta-blockers like propranolol should not be prescribed simultaneously in most cases. 2-agonist treatment has the potential to cause significant hypokalemia. Concomitant treatment with xanthine derivatives, steroids, diuretics, and hypoxia may intensify this impact, therefore use caution if you have acute severe asthma. In such cases, it is advised that serum potassium levels be monitored.
Contraindications
Salbutamol inhaler is contraindicated in patients with a history of hypersensitivity to salbutamol or any other components of Salbutamol inhaler.
Side Effect
Salbutamol is generally well tolerated. Few side effects have been observed during inhalation. There are tremors, anxiety, muscle cramps, headache, palpitation, a small compensatory increase in heart rate, cardiac arrhythmias (including atrial fibrillation, supraventricular tachycardia, and extrasystoles), tachycardia may occur in some patients. Mouth and throat irritation may occur with inhaled salbutamol
Pregnancy & Lactation
Pregnancy Classification C. In pregnant women, there are no sufficient and well-controlled studies using salbutamol inhalers or salbutamol sulfate. During pregnancy, this inhaler should only be used if the possible benefit outweighs the potential risk to the fetus. The components of the Salbutamol inhaler are not known to be excreted in human milk. When administering this inhaler to a nursing mother, exercise caution.
Precautions & Warnings
Storage Conditions
Pressure has been applied to the canister. Never pierce, damage, or burn a container, even if it seems to be empty. Avoid being in the sun's direct rays and intense heat. Keep the temperature below 30 degrees. Do not let yourself get icicle-like. Maintain a safe distance from the eyes. eschew contact with children. It can only be obtained with a prescription from a qualified doc
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