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Doxiva 400 is indicated for the management of:
- Asthma
- Chronic Obstructive Pulmonary Disease (COPD)
- Bronchospasm
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100% Genuine Products, Guaranteed
Safe & Secure Payments, Always
Fast, Secure & Efficient Delivery
Proper Packaging
- Cash on Delivery - All over Bangladesh
- Regular Delivery: 24-48 Hours, Dhaka City* Charge Tk.39-59
- Regular Delivery: 48-96 Hours, Other Cities* Charge Tk.99-125
- ফ্রি ডেলিভারিঃ - ২৯৯৯ টাকা+ অর্ডারে, ঢাকা
শহরে
- ফ্রি ডেলিভারিঃ - ৫৯৯৯ টাকা+ অর্ডারে, ঢাকার
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- Google Play Store থেকে ডাউনলোড
- Apple Store থেকে ডাউনলোড
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✅ Description:
Doxophylline is a newer bronchodilator belonging to the xanthine group. Structurally, it differs from theophylline due to the presence of a dioxolane group at position 7.
It works by selectively inhibiting phosphodiesterase-4 (PDE4), leading to relaxation of bronchial smooth muscles.
Compared to theophylline, it has lower affinity for adenosine receptors (A1 and A2), which contributes to a better safety profile and fewer side effects.
Relevant Products / প্রাসঙ্গিক পণ্য
✔️ Doxophylline is generally well tolerated, but may cause mild symptoms such as:
- Nausea and vomiting
- Headache
- Gastric discomfort
- Heartburn
✔️ Dosage & Administration | Doxophylline
Adults
- 400 mg tablet 2–3 times daily, or as directed by a physician
Elderly
- 200 mg tablet 2–3 times daily
Children
- >12 years: 200 mg tablet or 10 ml syrup 2–3 times daily
- 6–12 years: 6–9 mg/kg body weight twice daily
Sustained Release (SR) Form
- If the total daily dose is 400 mg, SR tablet may be taken once daily
Always follow the physician’s recommendation for dosing.
✔️ Interaction
- Avoid concurrent use with other xanthine derivatives
- May interact with:
- Ephedrine (risk of additive toxicity)
- Troleandomycin, lincomycin, clindamycin
- Allopurinol
- Cimetidine, ranitidine
- Propranolol
- Influenza vaccine
These may reduce liver clearance, increasing drug levels in the blood.
✔️ Contraindications
- Acute myocardial infarction
- Known hypersensitivity to doxophylline or its components
- Hypotension
- Breastfeeding (contraindicated in nursing mothers)
✔️ Pregnancy & Lactation
- Animal studies show no harm to the fetus, but human data is limited
- Should be used in pregnancy only if clearly necessary
- Contraindicated during breastfeeding
✔️ Precautions & Warnings
- Use cautiously in patients with:
- Liver disease
- Congestive heart failure
- Dose adjustments may be required when used with:
- Erythromycin, cimetidine, propranolol, etc. (may increase drug levels)
- Phenytoin, anticonvulsants, or smoking (may decrease drug levels)
✔️ Storage:
- Store in a cool, dry place
- Protect from light and moisture
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
