Lijenta-M 500 | Type II Diabetes Medicine | Online ePharma
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Lijenta-M 500mg Tablet 10pcs

Generic: Linagliptin + metformin hydrochloride

Type: Tablet

Pack Size: 10 Pcs

Linagliptin 2.5mg + Metformin Hydrochloride 500mg combination is used to treat high blood sugar levels caused by type 2 diabetes. 


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✅ Description:

Lijenta-M 500mg Tablet is a combination of Metformin and Linagliptin, used to manage type II diabetes mellitus in adults when diet, exercise, and other medications are insufficient. It helps control blood sugar levels when used alongside proper diet and exercise.

Type II Diabetes Mellitus:

  • Chronic condition with high blood glucose.
  • Caused by insufficient insulin production or poor cellular response to insulin.

Take with meals. Regular monitoring of blood sugar and kidney function by your doctor is advised. Inform your doctor if you have liver, kidney, or heart problems, or issues with blood circulation or dehydration. Not for patients with severe uncontrollable diabetes, alcoholism, or severe infections.

Safety Advices


Alcohol
UNSAFE

Avoid consumption of alcohol while taking Lijenta-M 500mg Tablet as it may increase the risk of unwanted side effects.


Pregnancy
CONSULT YOUR DOCTOR

It is not known whether the use of Lijenta-M 500mg Tablet could affect the unborn baby. Therefore, it should not be used during pregnancy unless recommended by your doctor.


Breastfeeding
CONSULT YOUR DOCTOR

It is not known whether the use of Lijenta-M 500mg Tablet could pass through the breast milk. Therefore, it should be used in breastfeeding only if the physician considers it necessary.


Driving
CAUTION

Lijenta-M 500mg Tablet has no influence on your ability to drive or handle heavy tools or machines. However, do not drive or operate any machines if your ability is affected by the Lijenta-M 500mg Tablet.


Kidney
CONSULT YOUR DOCTOR

Lijenta-M 500mg Tablet is not recommended for use in patients with severely reduced kidney functions. Therefore, consult your doctor before taking it.


Liver
CONSULT YOUR DOCTOR

Lijenta-M 500mg Tablet is not recommended for use in patients with severe liver problems. It should be used with caution in patients with gallstones. Therefore, consult your doctor before taking it.

Similar Products

✔️ Uses of Lijenta-M 500mg Tablet
  • Used to manage type II diabetes mellitus in adults
✔️ How does Lijenta-M 500mg Tablet work?

Linagliptin helps to control blood sugar levels by increasing substances in the body that make the pancreas release more insulin. It also signals the liver to stop producing sugar (glucose) when too much sugar is in the blood. Metformin reduces the absorption of sugar from the stomach, reduces the release of stored sugar from the liver, and helps your body use sugar better. 

✔️ Side Effects of Lijenta-M 500mg Tablet
  • Common: Nasopharyngitis and diarrhea.
  • Hypoglycemia is more common when used with sulfonylureas.
✔️ Quick Suggestions:
  • Metformin + Linagliptin should be taken with food to lower the chances of having an upset stomach.
  • Take it in addition to regular exercise and a healthy diet to lower the levels of blood sugar.
  • The chances of weight gain and low blood sugar are lower than that of other diabetes medicines.
  • Hypoglycemia (low blood sugar level) may occur when taken along with other antidiabetic medicines, alcohol, or by delaying/skipping a meal. Carry a sugar source with you for immediate relief.
  • Monitor your blood sugar level regularly while you are taking this medicine.
  • Inform your doctor about your diabetes treatment if you are due to have any surgery under a general anesthetic.
  • Tell your doctor immediately if you experience any deep or rapid breathing, persistent nausea, vomiting, or stomach pain as Metformin + Linagliptin may cause a rare but serious condition called lactic acidosis, which is an excess of lactic acid in the blood.
✔️ Indications:

Lijenta-M 500 is a combination of two medications that help people with type 2 diabetes mellitus manage their high blood sugar levels. This lessens your risk of developing serious diabetes complications like kidney damage and blindness and lowers your risk of a heart attack or stroke. It is possible to prescribe Lijenta-M 500 alone or in combination with other diabetes drugs.

✔️ Pharmacology

Linagliptin:

  • Used to enhance glycemic control in adults with type 2 diabetes mellitus.
  • Inhibits DPP-4 (dipeptidyl peptidase-4), which degrades incretin hormones (GLP-1 and GIP).
  • Increases active incretin hormones, stimulating insulin release from pancreatic beta cells and reducing glucagon secretion from alpha cells.

Metformin Hydrochloride:

  • A biguanide oral antihyperglycemic drug for managing type 2 diabetes.
  • Lowers both basal and postprandial plasma glucose.
  • Reduces hepatic glucose production, decreases intestinal glucose absorption, and enhances peripheral glucose uptake and utilization.
✔️ Dosage & Administration of Lijenta-M 500mg Tablet

Immediate Release Tablets:

  • Dosage is individualized based on effectiveness and tolerability.
  • Max recommended dose: 2.5 mg of Linagliptin and 1000 mg of Metformin twice daily with meals.
  • Starting dose for new patients: 2.5 mg Linagliptin and 500 mg Metformin twice daily.
  • Existing Metformin users: 2.5 mg Linagliptin with current Metformin dose twice daily.
  • Switching from individual components to combination: Match doses of each component.

Extended-Release Tablets:

  • Dosage is individualized based on effectiveness and tolerability.
  • Max recommended total daily dose: 5 mg Linagliptin and 2000 mg Metformin.
  • Starting dose for new patients: 5 mg Linagliptin/1000 mg Metformin once daily with a meal.
  • Existing Metformin users: 5 mg Linagliptin with a similar Metformin dose once daily with a meal.
  • Switching from the immediate release: Match the total daily dose of each component to the extended-release form.
✔️ Interaction
  • Cationic Drugs: Potential interaction with Metformin via renal tubular secretion; monitor patients closely.
  • Carbonic Anhydrase Inhibitors: Risk of metabolic acidosis; use cautiously with Metformin.
  • Inducers of P-glycoprotein and CYP3A4 Enzymes: May reduce Linagliptin efficacy; consider alternative treatments.
  • Drugs Affecting Glycemic Control: Monitor for hyperglycemia or hypoglycemia when adding or removing certain drugs.
✔️ Contraindications

Not suitable for patients with renal impairment, acute or chronic metabolic acidosis, or hypersensitivity to Linagliptin or Metformin.

✔️ Pregnancy & Lactation
  • Use only if needed during pregnancy.
  • Exercise caution when administering to lactating mothers.
✔️ Precautions & Warnings
  • Discontinue Metformin immediately in cases of lactic acidosis and provide supportive therapy.
  • Monitor for signs of acute pancreatitis; discontinue if suspected.
  • Temporarily discontinue radiologic studies with contrast or major surgeries.
  • Monitor hematologic parameters annually due to potential Vitamin B12 deficiency.
✔️ Storage Conditions:
  • Store in a cool, dry place below 30°C, protected from light and moisture.
  • Keep out of reach of children.
Frequently Asked Questions (FAQ)

A: Consume a sugary snack or drink and consult your doctor if symptoms persist.

A: Yes, increase fiber intake, drink water, and exercise regularly. Contact your doctor if this persists.

A: Consult your doctor before combining with blood pressure medications due to possible interactions.

A: Only use under medical supervision. Your doctor will determine the correct dose for you

A: Inform your doctor if you have liver, kidney, heart problems, severe infections, or dehydration. Follow prescribed diet and lifestyle changes.

A: No, higher doses can cause toxicity. Follow your doctor's prescribed dose.

A: No, consult your doctor before stopping to avoid reversal of symptoms.

A: Take it as soon as you remember unless it’s almost time for the next dose. Do not double the dose to catch up.

A: It is an antidiabetic medicine used with diet and exercise to control blood sugar levels in type II diabetes mellitus.

A: Consult your doctor before use during pregnancy.

A: Combining with insulin increases hypoglycemia risk. Consult your doctor before taking them together.

A: Nausea, diarrhea, stomach pain, constipation, loss of appetite, and metallic taste. Consult your doctor if these persist.

A: Take with meals to reduce gastrointestinal side effects. Consult your doctor for specific advice.

A: Take as long as prescribed by your doctor. They will determine the correct duration based on your condition.

A: Take it preferably after meals with water. Do not crush or chew. Follow your doctor's dosage instructions based on your condition.
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Check our pricing section for Lijenta-M 500mg Tablet 10pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
ePharma reserves the right to make adjustments to pricing, Products and Service offerings for reasons including, but not limited to, changing market conditions, Product discontinuation, Product unavailability, manufacturer price changes, supplier price changes and errors in advertisements. All orders are subject to Product availability and the availability of Personnel to perform the Services. Therefore, Seller cannot guarantee that it will be able to fulfill Customer’s orders. If Services are being performed on a time and materials basis, any estimates provided by Seller are for planning purposes only.

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