Deslor Syrup

✔️ Uses of Deslor Syrup

• Allergic rhinitis
• Urticaria

✔️ How does Deslor Syrup work?

Deslor 5 MG Tablet works by blocking the effects of a chemical messenger (histamine) in the body that causes allergic symptoms like itching and swelling, etc.

✔️ Side Effects of Deslor Syrup

• Shortness of breath
• Swelling of face, lips, eyelids, tongue, hands and feet
• Headache
• Dizziness
• Painful menstruation
• Muscle or joint pain
• Nausea or vomiting
• Sleepiness
• Fever
• Weakness

✔️ Quick Suggestions:

• Your doctor has prescribed Deslor Syrup to help relieve allergy symptoms such as itching, swelling, and rashes.
• As compared to other similar medications, it is much less likely to make you feel sleepy.
• Be cautious while driving or doing anything that requires concentration as it can cause dizziness and sleepiness.
• Do not drink alcohol while taking this medication as it may cause increased sleepiness.
• Stop taking Deslor Syrup at least three days before taking an allergy test as it can affect the test results.

✔️ Indication of Deslor Syrup

Allergic Rhinitis: Desloratadine is indicated for the relief of the nasal and non-nasal symptoms of allergic rhinitis (Both seasonal and perennial) in patients 2 years of age and older.

Chronic Idiopathic Urticaria: Desloratadine is also indicated for the symptomatic relief of pruritus, reduction in the number of hives, and size of hives, in patients with chronic idiopathic urticaria 2 years of age and older.

✔️ Pharmacology

Desloratadine, the primary active metabolite of Loratadine, is a non-sedating substance. It belongs to the class of long-acting tricyclic histamine antagonists and exhibits selective H1-receptor histamine antagonist activity. Desloratadine is effective in blocking the H1 receptors and preventing the effects of histamine in the body. Additionally, it can inhibit the release of histamine from mast cells in humans. This mechanism of action helps alleviate allergic symptoms without causing drowsiness.

✔️ Dosage & Administration of Deslor Syrup

Dosage instructions for the syrup form of the medication are as follows:

• Children aged 6-11 months: Take 2 ml of the syrup once daily.
• Children aged 1-5 years: Take 5 ml of the syrup once daily.
• Children aged 6-11 years: Take 5 ml of the syrup once daily.
• Adults and individuals aged 12 years and above: Take 10 ml of the syrup once daily.

✔️ Interaction

Some medicines can affect the way Deslor Syrup works or Deslor Syrup itself can reduce the effectiveness of other medicines taken at the same time. Tell your doctor about all the medicines, supplements, or herbals you are currently taking or might take to avoid any possible interaction.

✔️ Contraindications

Desloratadine is contraindicated in patients with known hypersensitivity to this medicine or to any of its ingredients or to loratadine.

✔️ Pregnancy & Lactation

The available data on the use of desloratadine in pregnancy are limited, and there is insufficient information to determine its potential risk for major birth defects and miscarriage. Adequate and well-controlled studies in pregnant women have not been conducted.

Regarding reproductive potential, there is no available data on the impact of desloratadine on human fertility. In studies conducted in rats, there were no clinically relevant effects on female fertility. However, in male rats, a decrease in fertility was observed at a high dose of desloratadine that was significantly higher than the recommended human dose.

Desloratadine and pseudoephedrine, another component of some formulations, can both pass into breast milk. There is not enough data on the effects of desloratadine on breastfed infants or its impact on milk production. The decision to continue breastfeeding or discontinue it should be made by considering the developmental and health benefits of breastfeeding, the clinical need of the nursing mother, and the potential adverse effects on the breastfed infant from the medication or the underlying maternal condition.

✔️ Precautions & Warnings

In adult patients with hepatic or renal impairment, it is recommended to start with a lower dose of desloratadine. A starting dose of one 5 mg tablet every other day is recommended based on pharmacokinetic data. This is done to account for the potential impact of impaired liver or kidney function on the clearance of the medication.

For patients with a medical or family history of seizures, caution should be exercised when prescribing desloratadine. Close monitoring may be necessary to assess the individual's response to the medication.

Desloratadine is not recommended for use in patients with severe renal or hepatic failure, children below 6 months of age, the elderly population, individuals with epilepsy, pregnant women, or breastfeeding mothers. The safety and effectiveness of desloratadine in these populations have not been established or sufficient data is not available.

Regarding lactation, it is unknown whether desloratadine is excreted in breast milk. Therefore, it is not recommended to use desloratadine during breastfeeding due to the lack of sufficient data on its effects on the breastfed infant.

✔️ Storage Conditions

Store in a cool & dry place, protected from light. Store below 30°C. Keep all medicines out of the reach of children.