Prelica CR 165 Tablet

✔️ Renal Impairment

Pregabalin is eliminated mainly through the kidneys, so the dose should be adjusted according to renal function. Lower doses are recommended when creatinine clearance is reduced. Patients receiving haemodialysis may require an additional dose after each dialysis session.

✔️ How to Take Prelica CR

Prelica CR should generally be taken once daily after an evening meal. Swallow the tablet whole with water; do not crush, chew, or split it.

If a dose is missed after the evening meal, specific timing instructions should be followed based on when the missed dose is remembered. Do not take extra doses to compensate.

When stopping pregabalin, treatment should be gradually reduced over at least one week rather than discontinued suddenly.

✔️ Drug Interactions

Pregabalin has relatively few significant pharmacokinetic drug interactions. However, caution is required when it is combined with other medicines that can cause sedation or respiratory depression.

✔️ Contraindication

Prelica CR should not be used in patients with known hypersensitivity to pregabalin or any component of the formulation.

✔️ Side Effects

• Dizziness
• Sleepiness
• Dry mouth
• Swelling of the hands, feet, or ankles
• Blurred vision
• Weight gain
• Difficulty concentrating or abnormal thinking

✔️ Pregnancy & Lactation

Adequate controlled studies in pregnant women are unavailable, so pregnant women should discuss the potential risks and benefits with their doctor.

Small amounts of pregabalin can pass into breast milk. Breastfeeding is generally not recommended during treatment because of potential risks.

✔️ Precautions & Warnings

Pregabalin may cause dizziness and drowsiness, which can affect driving and the ability to operate machinery. Avoid these activities until you know how the medicine affects you.

Rarely, angioedema involving the face, lips, tongue, throat, or airway may occur. Stop the medicine and seek immediate medical attention if swelling or breathing difficulty develops.

Pregabalin and other antiepileptic medicines may increase the risk of suicidal thoughts or unusual changes in mood or behaviour. Patients and caregivers should monitor for these changes.

Respiratory depression may occur, particularly when pregabalin is combined with other central nervous system depressants or in patients with underlying respiratory problems.

Peripheral edema may occur, and caution is advised when pregabalin is used with thiazolidinedione antidiabetic medicines.

✔️ Storage:

Store below 30°C in a cool, dry place protected from light and moisture. Keep out of reach of children.