Pregaben 50 30Pcs (Box) - ePharma
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Pregaben 50mg (30pcs Box)

Generic: Pregabalin

Type: Capsule

Pack Size: 30 Pcs

Generic Name: Pregabalin 50mg

Manufacturer: Incepta Pharmaceuticals Ltd.


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Discount Price: ৳ 385.02
MRP: ৳ 414 7% Off

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Description:

Indications

Pregabalin is indicated for:

Management of neuropathic pain associated with diabetic peripheral neuropathy

Treatment of postoperative neuralgia

Adjunctive treatment of adult patients with partial seizures

Management of fibromyalgia

Pain neuropathic associated with spinal cord injury.

 

Pharmacology

Pregabalin is a structural derivative of the inhibitory neurotransmitter gamma-aminobutyric acid (GABA). It does not bind directly to GABAA, GABAB receptors, or benzodiazepines. Pregabalin binds with high affinity to the alpha 2delta site (an accessory subunit of voltage-evaluated calcium channels) in tissues of the central nervous system. The oral bioavailability of pregabalin is ≥90% and is independent of dose. It is eliminated from the systemic circulation mainly by renal excretion as an unchanged drug with a mean half-life of 6.3 hours in subjects with normal renal function.

 

Dosage & Administration

Neuropathic Pain Associated with Diabetic Peripheral Neuropathy: The maximum recommended dose of pregabalin is 100 mg three times daily (300 mg/day) in patients with creatinine clearance of at least 60 ml / min. . The dose should start at 50 mg three times a day (150 mg/day) and may be increased to 300 mg/day in 1 week depending on effectiveness and tolerability.

Back neuralgia: The recommended dose of pregabalin is 75 to 150 mg twice daily, or 50 to 100 mg three times daily (150 to 300 mg/day) in patients with low creatinine clearance. at least 60 mL/min. The dose should start at 75 mg twice a day or 50 mg three times a day (150 mg/day) and can be increased to 300 mg/day in 1 week depending on effectiveness and tolerability.

Add-on therapy for adult patients with partial epilepsy: In general, it is recommended that patients start a total daily dose of no more than 150 mg/day (75 mg twice daily, 50 mg/day, or 50 mg/day). day). mg three times a day). Depending on individual patient response and tolerability, the dose may be increased up to a maximum dose of 600 mg/day.

Management of fibromyalgia: The recommended dose of pregabalin for fibromyalgia is 300-450 mg/day. Dosage should start at 75 mg twice/day (150 mg/day) and may be increased to 150 mg twice/day (300 mg/day) for 1 week depending on efficacy and tolerability. .

Neuropathic pain associated with spinal cord injury: The recommended dose range is 150-600 mg/day. The recommended starting dose is 75 mg twice/day (150 mg/day). The dose can be increased to 150 mg twice a day (300 mg/day) in 1 week depending on the effectiveness and tolerance. Pregabalin capsules can be taken without regard to meals.

Interaction

There are no significant interactions between pregabalin and other anti-epileptic drugs and oral contraceptives. Pregabalin may potentiate the effects of ethanol and lorazepam.

Contraindications

Pregabalin is contraindicated in patients with known hypersensitivity to Pregabalin or any of its ingredients.

Side Effects

The most common side effects are dizziness, drowsiness, dry mouth, edema, blurred vision, weight gain, and unusual thoughts.

Pregnancy & Lactation

Pregabalin's pregnancy category is C. It should therefore only be used if the potential benefit outweighs the possible risk to the fetus. Pregabalin can be secreted into breast milk like other drugs and should therefore be administered to a nursing woman only if the benefits clearly outweigh the risks.

Precautions & Warnings

Stopping pregabalin without reducing the dose may cause insomnia, nausea, headache, and diarrhea. Therefore, it should be gradually reduced for at least 1 week, without stopping abruptly. Creatinine kinase may be elevated during treatment with pregabalin. The drug should be stopped promptly if myopathy is diagnosed or suspected or if creatinine kinase is markedly elevated.

Storage Conditions

Keep in a cool & dry place (below 30° C), protected from light & moisture. Keep out of the reach of children.

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Check our pricing section for Pregaben 50mg (30pcs Box) price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

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ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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