Nervion 15 | Adjunct & Primary Anti-epileptic Drugs
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Nervion 15

Generic: Mirogabalin Besylate

Type: Tablet

Pack Size: 10 Pcs

Nervion is prescribed for the management of:

  • Diabetic Peripheral Neuropathic Pain (DPNP)
  • Postherpetic Neuralgia (PHN)
  • Peripheral Neuropathic Pain (PNP)

Discount Price: ৳ 428
MRP: ৳ 450 5% Off

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  • Regular Delivery Regular Delivery: 24-48 Hours, Dhaka City* Charge Tk.39-59
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✅ Description:

Mirogabalin, a derivative of gamma-amino acids, selectively binds to the α2δ subunit of voltage-gated calcium channels (VGCCs). Reducing calcium influx into presynaptic neurons suppresses neurotransmitter release and decreases CNS hyperexcitability.

  • Absorption: Rapid, peak plasma levels within 0.5–1.5 hrs
  • Protein Binding: ~25% (low)
  • Distribution: 64–88 L
  • Metabolism: Mostly unchanged via renal excretion; 13–20% by UGT enzymes
  • Elimination Half-life: 2–4.9 hrs
  • Excretion: ~99% through urine

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✔️ Composition

Mirogabalin Besylate

✔️ Dosage & Administration

Adults: Start with 5 mg twice daily, titrate weekly by 5 mg to a maximum of 15 mg twice daily.

Renal Impairment:

Mild: 5 mg BID → up to 10 mg BID

Moderate: 2.5 mg BID → up to 7.5 mg BID

Severe: 2.5 mg once daily → up to 7.5 mg once daily

Children/Adolescents: Safety not established

Hepatic Impairment: Mild–moderate safe; no data for severe

✔️ Drug Interactions

↑ Plasma levels with Cimetidine, Probenecid

CNS depression potentiated with Lorazepam or alcohol

Substrate of OAT1, OAT3, OCT2, MATE1, MATE2-K, UGT → inhibitors may increase exposure

Food: No significant impact

✔️ Contraindications

Hypersensitivity to Mirogabalin

Patients with significant hepatic or renal impairment

✔️ Side Effects

Common: Somnolence, dizziness, edema, weight gain

Serious (rare):

Loss of consciousness, confusion

Liver dysfunction (jaundice, nausea, vomiting)

Visual disturbances (blurred/double vision)

✔️ Pregnancy & Lactation

Use only if benefits outweigh risks (animal studies show placental transfer).

Excreted in breast milk – weigh maternal benefit vs infant risk.

✔️ Precautions & Warnings
  • May cause dizziness, somnolence → avoid driving or operating machinery.
  • Risk of falls & fractures in elderly.
  • Weight gain possible.
  • Dose adjustment required in renal dysfunction.
  • Seek medical advice if allergic reaction or vision problems occur.
✔️ Storage:

Store below 30°C, in a dry place away from light & moisture.
Keep out of reach of children.

Frequently Asked Questions (FAQ)

The latest Nervion 15 price in Bangladesh is shown on this page. Price may change depending on stock, pack size, and active offers.

Yes, you can order Nervion 15 online from ePharma when it is available in stock. Delivery options depend on your location in Bangladesh.

Prescription requirements can vary by product type. Please follow the product label and consult a qualified healthcare professional when needed.

Nervion 15 is from ACI Limited. Please check the product details section for updated manufacturer and product information.

The listed pack size for Nervion 15 is 10 Pcs.
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⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

📦Pricing Information, Availability:
Product Availability & Pricing Notice Please note that pricing, availability, and service offerings are subject to change due to: Market fluctuations, Manufacturer or supplier adjustments, Product discontinuation or temporary unavailability, Advertising errors. All orders depend on stock availability and staff resources. If services are provided on a time-and-materials basis, any shared estimates are for planning purposes only.

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