Rosuva 10mg Tablet

Uses of Rosuva 10mg Tablet

• Treats high blood cholesterol levels
• Prevents the risk of heart attack or stroke

How does Rosuva 10mg Tablet work?

Indeed, Rosuva 10mg Tablet is a lipid-lowering medication that effectively lowers levels of LDL (low-density lipoprotein) cholesterol, commonly known as "bad" cholesterol, as well as triglycerides. It achieves this by inhibiting the activity of an enzyme called HMG-CoA reductase, which plays a crucial role in synthesizing cholesterol in the body. By blocking this enzyme, Rosuva 10mg Tablet reduces the production of cholesterol.

Additionally, this medication works on the liver to enhance its ability to remove lipid particles from the bloodstream. By improving the clearance of these particles, Rosuva 10mg Tablet further lowers blood cholesterol levels and helps prevent the associated risks linked to high cholesterol.

Overall, Rosuva 10mg Tablet effectively reduces LDL cholesterol and triglyceride levels, thereby reducing the risk of complications associated with high cholesterol levels.

Side Effects of Rosuva 10mg Tablet

• Muscle pain
• Weakness
• Headache
• Joint pain
• Constipation
• Nausea
• Stomach pain
• Difficulty or painful urination
• Dark colored urine
• Dizziness

Quick Suggestions:

• Rosuva 10mg Tablet is a medication used for treating high cholesterol levels by reducing "bad" cholesterol (LDL) and triglycerides in the body. It should be taken along with regular exercise and a low-fat diet.
• In general, Rosuva 10mg Tablet is considered safe. However, it may cause certain side effects such as diarrhea, gas, or an upset stomach. If you experience any of these, taking the medication with food may help alleviate these symptoms.
• It is essential to inform your doctor if you experience fatigue, weakness, or pain while taking Rosuva 10mg Tablet. Your doctor may also monitor your liver function before starting the treatment and regularly thereafter. If you notice any signs of liver problems such as stomach pains, dark urine, or yellowing of the skin or eyes, inform your doctor immediately.
• Maintaining a healthy weight within the BMI range of 19.5-24.9 is recommended. Regular physical activity or exercise is also beneficial. A diet rich in whole grains, fruits, vegetables, and low-fat dairy products is advised. Quitting smoking is highly recommended to lower the risk of heart disease.
• Managing stress is important for heart health. Engage in activities you enjoy and spend time with loved ones. Practice mindfulness techniques to cope with stress. Additionally, incorporating foods and drinks containing heart-healthy omega-3 fatty acids into your daily diet is beneficial.
• Before starting treatment with Rosuva 10mg Tablet, inform your doctor if you have kidney disease, liver disease, or diabetes. If you have diabetes, it is important to monitor your blood sugar levels regularly as Rosuva 10mg Tablet may cause an increase in blood sugar levels.
• Lastly, it is crucial not to take Rosuva 10mg Tablet if you are pregnant, planning a pregnancy, or breastfeeding. Consult your doctor for alternative options in these situations.

Indication of Rosuva 10mg Tablet

Rosuva 10mg Tablet is used to lower the cholesterol level in the body.

Pharmacology

Rosuvastatin is a selective and competitive inhibitor of HMG-CoA reductase, the enzyme responsible for converting 3-hydroxy-3-methyl glutaryl coenzyme A to mevalonate, a precursor of cholesterol. Rosuvastatin exerts its lipid-modifying properties in two ways. First, it increases the number of hepatic LDL receptors on the cell surface, which improves LDL absorption and catabolism. Second, rosuvastatin suppresses hepatic VLDL production, lowering the overall amount of VLDL and LDL particles.

Dosage & Administration of Rosuva 10mg Tablet

• The dosing range for Rosuva 10mg Tablet is typically 5-40 mg once daily. The 40 mg dose should only be used for patients who are not able to achieve their LDL-C (low-density lipoprotein cholesterol) goal with the 20 mg dose.
• For patients with HoFH (heterozygous familial hypercholesterolemia), the starting dose is usually 20 mg per day.
• In pediatric patients with HeFH (heterozygous familial hypercholesterolemia), the recommended dose is 5-10 mg per day for patients aged 8 to less than 10 years and 5-20 mg per day for patients aged 10 to 17 years.
• For pediatric patients with HoFH, the recommended dose is 20 mg per day for patients aged 7 to 17 years.

Rosuva 10mg Tablet can be taken with or without food, at any time of the day. Take Rosuva 10mg Tablet as advised by your physician. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Rosuva 10mg Tablet can be taken with or without meals. Your doctor will determine the appropriate dose and length of therapy for you based on your age, body weight, and medical condition. Do not discontinue Rosuva 10mg Tablet without first seeing your doctor.

Interaction

Rosuva 10mg Tablet has several contraindications and potential interactions with other medications and conditions. Here is a summary of those interactions:

• Alcoholic beverages should be avoided while taking Rosuva 10mg Tablet.
• Rosuva 10mg Tablet may interact with certain disease conditions, including neuromuscular disorders (myopathy, myoneural disorder), thyroid gland problems (hypothyroidism), and renal dysfunction.

Contraindications

Contraindications with Medications:

• Cyclosporine (organ transplant medicine)
• Warfarin or clopidogrel (blood thinners)
• Fibrates (gemfibrozil, fenofibrate)
• Ezetimibe (a medicine used to lower cholesterol)
• Antacids (aluminum hydroxide, magnesium hydroxide)
• Antibiotics (erythromycin, fusidic acid)
• Oral contraceptive pills
• Regorafenib (anti-cancer medication)
• Anti-viral or anti-HIV drugs (ritonavir, lopinavir, atazanavir, simeprevir, ombitasvir, paritaprevir, dasabuvir, velpatasvir, grazoprevir, elbasvir, glecaprevir, and pibrentsavir)

Pregnancy & Lactation

Pregnant women's safety has not been demonstrated. It is unknown whether or not Rosuvastatin is excreted in human milk.

Precautions & Warnings

Prolonged intake of Rosuva 10mg Tablet may potentially lead to muscular disorders such as myopathy and rhabdomyolysis, which can cause kidney damage. Therefore, it is important to be aware of and monitor for any signs of muscle-related symptoms while taking this medication.

Individuals who consume excess alcohol or have liver disease should consult their doctor before taking Rosuva 10mg Tablet, as the combination of alcohol and liver disease can increase the risk of liver-related complications.

• Caution should be exercised if you are taking any blood thinners or anticoagulants like warfarin or coumarin while on Rosuva 10mg Tablet, as there may be an increased risk of bleeding. Regular monitoring and adjustment of the anticoagulant dose may be necessary in such cases.
• If you are taking antacids containing magnesium hydroxide or aluminum hydroxide, it is recommended to maintain at least a 2-hour gap between the intake of Rosuva 10mg Tablet and the antacids. This helps to prevent any potential interference with the absorption of the medication.
• Rosuva 10mg Tablet may cause increases in HbA1c (glycated hemoglobin) and fasting glucose levels. If you regularly take this medication, it is advisable to inform your doctor before undergoing diabetes tests to ensure an accurate interpretation of the results.
• For patients with proteinuria (protein in urine) or hematuria (blood in urine), it is important to inform the doctor before starting Rosuva 10mg Tablet, as dose adjustments may be required based on the individual's condition.
• Regular liver enzyme tests are recommended for individuals who are regularly taking Rosuva 10mg Tablet to monitor liver function and detect any potential liver-related side effects.
• It is crucial to communicate with your doctor about any existing medical conditions, medications, or concerns before starting or continuing treatment with Rosuva 10mg Tablet. Your doctor will provide appropriate guidance and monitor your health accordingly.

Storage Conditions

• Store Rosuva 10mg Tablet at or below 25°C.
• Keep it away from children and pets.
• Protect it from moisture and direct sunlight.
• Avoid using expired medicine that you no longer need.