Rosuva 5mg Tablet

✔️ Uses of Rosuva 5

• High Cholesterol
• Prevention of heart attack and stroke

✔️ Side Effects of Rosuva 5

• Muscle pain
• Weakness
• Headache
• Abdominal pain

✔️ Quick Suggestions:

• Rosuvastatin is usually taken once daily, with or without food.
• It is important to follow a healthy diet and exercise regularly while taking rosuvastatin.
• Do not take rosuvastatin if you are pregnant or breastfeeding, or if you have liver disease.
• Your doctor may perform a liver function test before beginning treatment and on a regular basis thereafter. Notify your doctor if you notice any symptoms of liver disease, such as stomach pains, unusually dark urine, or yellowing of the skin or eyes.
• Before beginning treatment with this medicine, tell your doctor if you have kidney disease, liver disease, or diabetes. If you have diabetes, keep a close eye on your blood sugar levels because Rosuva 5 may cause an increase.
• Tell your healthcare provider about all medications, supplements, and vitamins you are taking before starting rosuvastatin.

✔️ Indications of Rosuva 5

• Reduce your "bad" cholesterol level (low-density lipoprotein, LDL)
• Increase your "good" cholesterol level (high-density lipoprotein, HDL)
• Reduce the amount of fat in your blood (triglycerides)
• Slow the formation of fatty deposits (plaque) in blood vessel walls.

✔️ Pharmacology

Rosuvastatin is an HMG-CoA reductase inhibitor that is both selective and competitive. The rate-limiting enzyme in the conversion of 3-hydroxy methyl glutaryl-CoA to mevalonate is HMG-CoA reductase (the precursor of cholesterol). Rosuvastatin exerts its lipid-modifying effect in two ways. First, it increases the number of liver low-density lipoprotein receptors on the cell surface, which improves low-density lipoprotein absorption and catabolism. Second, rosuvastatin reduces the total number of VLDL and LDL particles by inhibiting VLDL synthesis in the liver.

✔️ Dosage & Administration of Rosuva 5

Adults:

• The dosage range for rosuvastatin tablets: is 5-40 mg once daily.
• Only use 40 mg if patients are not meeting their LDL cholesterol goal with 20 mg.
• For adults with homozygous familial hypercholesterolemia: 20 mg/day as a starting dose.

Pediatric patients

• Pediatric patients with homozygous familial hypercholesterolemia: 20 mg/day for children aged 7 to 17.
• Pediatric patients with heterozygous familial hypercholesterolemia should take 5 to 10 mg/day if they are 8 to less than 10 years old, and 5 to 20 mg/day if they are 10 to 17 years old.

Renal Dose

• Renal dysfunction Severe (CrCl 30 mL/min/1.73m2) without hemodialysis: Reduce the starting dose to 5 mg PO qDay; do not exceed 10 mg PO qDay if CrCl is greater than 30mL/min/1.73m2. No dose adjustment is required.

The dosage of rosuvastatin varies depending on the individual's medical condition and response to treatment. The recommended starting dose for most adults is usually 5 to 10 mg once daily, taken at any time of the day, with or without food.

✔️ How to use Rosuva 5

Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Rosuva 5 may be taken with or without food, but it is better to take it at a fixed time.

✔️ How Rosuva 5 works

Rosuva 5 is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required by the body to make cholesterol, thereby lowering "bad" cholesterol (LDL) and triglycerides and raising "good" cholesterol (HDL).

✔️ What if you forget to take Rosuva 5?

If you miss a dose of Rosuva 5, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not take two doses within 12 hours.

✔️ What if you Overdose Rosuva 5

If you take too much rosuvastatin or overdose, call your doctor or go to the nearest hospital emergency room right away.

✔️ Interaction of Rosuva 5

Warfarin and oral contraceptives may cause an increase in serum levels. Itraconazole and HIV protease inhibitors may raise serum levels. Erythromycin and antacids may lower serum levels. Fenofibrate and niacin may increase the risk of myopathy. Potentially fatal: Gemfibrozil and ciclosporin increase the risk of rhabdomyolysis

✔️ Contraindications

It is known to be allergic to product ingredients, ban rosuvastatin Liver disease, which may include persistent and unexplained elevated liver transaminase levels Pregnant women and women who may become pregnant Nursing mothers

✔️ Pregnancy & Lactation

The safety of women has not been established during pregnant women. Tell your doctor if you are breastfeeding or plan to breastfeed. Medicines like rosuvastatin can pass into your breast milk and may harm your baby. Talk to your doctor about the best way to feed your baby if you take this medication.

✔️ Precautions & Warnings

Effects on skeletal muscle (eg, myopathy and rhabdomyolysis): risk increases with the use of 40 mg doses, advanced age (> 65 years), hypothyroidism, renal failure, and interactions with cyclosporine, lopinavir/tritone Weir, atazanavir/ritonavir, or some Other lipid-lowering drugs are used in combination. Patients should be advised to report unexplained muscle pain, tenderness, or weakness early. If signs or symptoms appear, rosuvastatin can be stopped. 

Abnormal liver enzymes and monitoring: Continuous elevation of liver transaminases may occur. Liver enzymes should be monitored before and during treatment.

• Do not take Rosuva 5 if you are pregnant, planning a pregnancy or breastfeeding.

✔️ Storage Conditions

Keep below 30oC temperature, protected from light & moisture. Keep out of the reach of children.