Rosutin 10mg Tablet 15Pcs

✔️ Uses of Rosutin 10

• Treats high blood cholesterol levels
• Prevention of heart attack and stroke

✔️ How Rosutin 10 works

Rosutin 10 is a lipid-lowering medication (statin). It works by blocking an enzyme (HMG-CoA-reductase) that is required by the body to make cholesterol, thereby lowering "bad" cholesterol (LDL) and triglycerides and raising "good" cholesterol (HDL).

✔️ What if you forget to take Rosutin 10?

Take Rosutin 10 as soon as you remember if you forget a dosage. If your next dosage is approaching, forego the missed one and resume your normal timetable. Never consume two dosages in 12 hours.

✔️ Side effects of Rosutin 10

• Muscle pain
• Weakness
• Headache
• Abdominal pain

✔️ Quick Suggestions:

• Rosutin 10 lowers triglycerides and "bad" cholesterol (LDL) to address elevated cholesterol. (fats). It should be consumed in addition to a low-fat diet and frequent exercise.
• Rosutin 10 is secure in general. It might result in flatulence, bloating, or gastrointestinal discomfort. Take it with meals if any of these scenarios apply to you.
• If you experience exhaustion, muscular weakness, or discomfort, let your doctor know.
• Your practitioner may perform routine liver function tests both before and after the course of therapy. If you experience symptoms of a liver condition, such as abdominal discomfort, abnormally black urine, or yellowing of the skin or eyes, let your doctor know right away.
• If you have diabetes, check your blood sugar levels frequently because Rosutin 10 may make them go up.
• If you are nursing, pregnant, or contemplating a baby, do not take Rosutin 10.
• The greatest method to reduce the chance of heart disease is to stop smoking.
• Avoid long-term worry. To reduce stress and exercise mindfulness methods, try to appreciate and spend time with your loved ones. 
  Incorporating foods and beverages that contain heart-healthy omega-3 fatty acids into your everyday diet.
• Maintain healthy weight management with a BMI of 19.5-24.9.
  Engage in frequent exercise or physical exertion.

✔️ Indications of

The use of rosuvastatin is advised in the following situations:

• Hypercholesterolemia Heterozygous (Familial and Nonfamilial)
• Hypercholesterolemia Homozygous (Familial)
• Mixed dyslipidemia (Fredrickson Type IIa and IIb)
• Primary protection against cardiovascular illness

✔️ Pharmacology

HMG-CoA reductase, the enzyme that turns 3-hydroxy-3-methyl glutaryl coenzyme A into mevalonate, a precursor to cholesterol, is selectively and aggressively inhibited by rosuvastatin. There are two methods that rosuvastatin uses its lipid-modifying abilities. It enhances LDL uptake and catabolism by first increasing the amount of hepatic LDL receptors on the cell membrane. Second, rosuvastatin reduces total levels of VLDL and LDL particles by inhibiting liver VLDL synthesis.

✔️ Dosage & Administration

• Rosuvastatin can be taken with or without food, at any time of day.

Oral hypertriglyceridemia, combined dyslipidemia, hyperlipidemia, and hypercholesterolemia prevention of cardiovascular events in individuals at elevated risk-

Adult: 

• Start with 5 or 10 milligrams once daily; if needed, raise the dosage to 20 mg daily at intervals of 4 weeks. 40 milligrams max. once daily.
• Use is not advised if there is an active hepatic illness.

Child Familial Hypercholesterolemia: 

• >10 Years 5 milligrams once daily at first, with adjustments possible after at least 4 weeks.
• 20 milligrams maximum, once daily.

Renal Dose

Renal Dysfunction Not on hemodialysis and severe (CrCl 30 mL/min/1.73m2):

• Reduce starting dosage to 5 mg PO qDay; do not surpass 10 mg PO qDay if CrCl is greater than 30 mL/min/1.73 m2: No dose modification is required

✔️ Interactions

There are several noteworthy drug interactions with rosuvastatin.

• Cyclosporine and rosuvastatin together increase the sensitivity to rosuvastatin.
• Rosuvastatin should only be taken in doses of 5 milligrams once daily.
  Gemfibrozil should not be combined with.
• If taken simultaneously, the rosuvastatin dose should be decreased to 10 mg once daily.
• Rosuvastatin intake is increased when lopinavir and ritonavir or atazanavir and ritonavir are combined. 10 milligrams of rosuvastatin should be given once daily.
• Anticoagulant coumarins: The combo raises the globally standardized percentage. (INR). INR should be steady before starting Rosuvastatin.
• The INR should be monitored frequently when beginning or stopping Rosuvastatin therapy until it achieves a stable number.
• Combining fibrates and niacin products with concurrent lipid-lowering treatments raises the chance of adverse effects on the skeletal muscle.

✔️ Contraindications

Rosuvastatin should be avoided if you have any of the following conditions:

• Liver illness, characterized by unexplained chronic increases in hepatic transaminase levels
• Hypersensitivity to product components is known.
• Women who are pregnant or may become pregnant
• Mothers who are breastfeeding

✔️ Pregnancy & Lactation

Pregnant women's safety has not been demonstrated. It is unknown whether or not Rosuvastatin is excreted in human milk.

✔️ Precautions & Warnings

• Skeletal muscle effects, such as myopathy and rhabdomyolysis: The hazards increase with the use of a dose of 40 mg, advanced age (>65 years), hypothyroidism, renal failure, and use in combination with cyclosporine, lopinavir/ritonavir, atazanavir/ritonavir, or other lipid-lowering drugs. Patients should be encouraged to report any inexplicable muscle pain, weakness, or distress right away. It is possible to cease taking rosuvastatin if signs or symptoms appear.
• Monitoring for abnormalities in liver enzymes: Hepatic transaminases may become persistently elevated.
• Measurements of liver enzymes should be made both before and during treatment.

✔️ Storage Conditions

Maintain a temperature of less than 30oC and keep it away from light and moisture. Keep out of children's reach.