Olopatadine is an anti-allergic molecule that works via several mechanisms. As a mast cell stabilizer, it stabilizes rodent basophils and human conjunctival mast cells and inhibits the immunologically stimulated release of histamine. Olopatadine acts as an antagonist at the histamine H1 receptors with high selectivity. Upon binding, olopatadine blocks the H1 receptor signaling pathway, inhibiting the release of inflammatory mediators, such as tryptase, prostaglandin D2, TNF-alpha, as well as pro-inflammatory cytokines. Olopatadine, an antihistamine, works by blocking the action of histamine in the body, which reduces allergy symptoms. Olopatadine hydrochloride treats sneezing, itching, runny nose, and other nasal symptoms of allergies.
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Olpadin 0.7% eye drops are indicated for the treatment of signs and symptoms (itchy, watery, red, and swollen eyes and/or eyelids) of allergic conjunctivitis, including vernal keratoconjunctivitis, vernal keratitis, blepharitis, blepharoconjunctivitis, and giant papillary conjunctivitis.
Store at room temperature and protect from light. It is desirable that the contents should not be used more than one month after first opening of the bottle.
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