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Qmax 25 | 1 Strip

Generic: Quetiapine

Type: Tablet

Pack Size: 10 Pcs

Qmax is indicated for:

  • Acute and chronic psychoses, including schizophrenia.
  • Bipolar disorder, including:
  • Treatment of manic episodes meeting DSM-IV criteria.
  • Treatment of depressive episodes.
  • Maintenance therapy in bipolar I disorder, in combination with a mood stabilizer, for preventing recurrence of manic, depressive, or mixed episodes.

Elderly: Slower titration and lower doses may be required. Clearance is reduced by 30–50%.

Children/Adolescents (<18 years): Not recommended.

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✅ Description:

Quetiapine Fumarate is an atypical antipsychotic belonging to the dibenzothiazepine class.

It acts as an antagonist at multiple brain neurotransmitter receptors:

  • Serotonin (5HT1A, 5HT2)
  • Dopamine (D1, D2)
  • Histamine (H1)
  • Adrenergic (α1, α2)

It has negligible affinity for muscarinic cholinergic and benzodiazepine receptors.

The therapeutic effect in schizophrenia is thought to result from a combination of dopamine D2 and serotonin 5HT2 antagonism.

Histamine H1 antagonism may explain sedation, while α-adrenergic blockade may contribute to orthostatic hypotension.

  1. Suicidal thoughts/behavior: Monitor patients with depression until remission.
  2. Orthostatic hypotension: Use caution in patients with cardiovascular or cerebrovascular disease.
  3. Seizures: Use cautiously in patients with seizure history.
  4. Tardive Dyskinesia / EPS: Consider dose reduction or discontinuation if symptoms appear.
  5. Neuroleptic Malignant Syndrome (NMS): Discontinue immediately if suspected.
  6. QT prolongation: Use with caution in at-risk patients.
  7. Neutropenia: Rare but possible; monitor CBC.
  8. Hyperglycemia/Diabetes: Monitor blood glucose in at-risk patients.

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✔️ Dosage & Administration

Schizophrenia & chronic psychoses:

  • Day 1: 50 mg
  • Day 2: 100 mg
  • Day 3: 200 mg
  • Day 4: 300 mg

Effective dose range: 300–450 mg/day, titrated as needed (150–750 mg/day possible).

Administered twice daily, with or without food.

Manic episodes (bipolar disorder):

Day 1: 100 mg → Day 4: 400 mg

Up to 800 mg/day by Day 6 (increments ≤200 mg).

Effective range: 400–800 mg/day.

Twice daily, with or without food.

Depressive episodes (bipolar disorder):

At bedtime: start 50 mg (Day 1) → 300 mg (Day 4).

May increase to 400 mg (Day 5) and 600 mg (Day 8).

Usual effective dose: 300 mg/day.

Maintenance (bipolar I disorder, with mood stabilizer):

Continue same effective dose from acute phase.

Typically 400–800 mg/day, administered twice daily.

✔️ Side Effects

Most commonly reported adverse effects include:

  • Somnolence, dizziness, dry mouth.
  • Discontinuation/withdrawal symptoms.
  • Lipid changes: ↑ triglycerides, ↑ LDL cholesterol, ↓ HDL cholesterol.
  • Weight gain, reduced hemoglobin.
  • Extrapyramidal symptoms (EPS).
✔️ Drug Interactions

Use caution with drugs that prolong QT interval or cause electrolyte imbalance.

Thioridazine, carbamazepine, and phenytoin increase the clearance of Quetiapine.

Enzyme inducers may lower plasma levels of Qmax.

✔️ Contraindications

Known hypersensitivity to Quetiapine or any component of the formulation.

✔️ Pregnancy & Lactation

Safety not established. Use only if potential benefits outweigh risks.

Excretion into human milk unknown → breastfeeding is not recommended during treatment.

✔️ Overdose Effects
  • Survival reported after ingestion up to 30 g.
  • No specific antidote.
  • Management: airway support, oxygenation, cardiovascular monitoring, IV fluids.
  • Avoid adrenaline/dopamine (risk of worsening hypotension due to α-blockade).
  • Continuous monitoring required until recovery.
✔️ Storage:

Store in a cool, dry place, away from light.

Keep out of reach of children.

Frequently Asked Questions (FAQ)

The latest Qmax 25 | 1 Strip price in Bangladesh is shown on this page. Price may change depending on stock, pack size, and active offers.

Yes, you can order Qmax 25 | 1 Strip online from ePharma when it is available in stock. Delivery options depend on your location in Bangladesh.

Qmax 25 | 1 Strip is a prescription medicine. Please use it only as advised by a registered physician.

Qmax 25 | 1 Strip is from ACI Limited. Please check the product details section for updated manufacturer and product information.

The listed pack size for Qmax 25 | 1 Strip is 10 Pcs.
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⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.

📦Pricing Information, Availability:
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