Ovocal Plus is indicated in-
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Nutrition is the most important to prevent osteoporosis and other bone-related diseases. Calcium, Magnesium & Vitamin D3 are the macronutrients for bone. Without Vitamin D3, very little Calcium is absorbed. Like Calcium, Magnesium increases bone strength and rigidity. Recent epidemiological studies showed that some micronutrients like Copper, Manganese, Zinc & Boron play an important role in bone health. Deficiency of micronutrients is noticed in patients with osteoporosis.
Adult: 1 film-coated tablet twice daily, preferably 1 tablet in the morning and 1 tablet in the evening or as directed by the physician. It is best taken with or just after main meals with a full glass of water.
Children 3-7 years: 1 effervescent tablet daily.
7 years and older: 1 to 2 effervescent tablets daily.
The use of calcium supplements has rarely given rise to mild gastrointestinal disturbances such as constipation, flatulence, nausea, gastric pain, and diarrhea. Following administration of vitamin-D3 supplements, an occasional skin rash has been reported. Hypercalciuria and, in rare cases, hypercalcaemia have been seen with long-term treatment at high doses.
The risk of hypercalcemia should be considered in patients taking thiazide diuretics since these drugs can reduce urinary calcium excretion. Hypocalcaemia must be avoided in digitalized patients. Certain foods (e.g.,, those containing oxalic acid, phosphate, or phytinic acid) may reduce the absorption of calcium. Concomitant treatment with phenytoin or barbiturates can decrease the effect of Vitamin-D 3 because of metabolic activation. Concomitant use of glucocorticoids can decrease the effect of Vitamin D3. The effects of digitalis and other cardiac glycosides may be attenuated with the oral administration of calcium combined with Vitamin-D 3 . Strict medical supervision is needed, and, if necessary, monitoring of ECG and calcium. Calcium salts may reduce the absorption of thyroxin, bisphosphonates, sodium fluoride, quinolone, tetracycline antibiotics, or iron. It is advisable to allow a minimum period of four hours before taking the calcium.
Absolute contraindications are hypercalcaemia resulting from myeloma, bone metastasis or other malignant bone disease, sarcoidosis, primary hyperparathyroidism, and Vitamin-D 3 overdosage, and severe renal failure. Hypersensitivity to any of the tablet ingredients. Relative contraindications are osteoporosis due to prolonged immobilisation, renal stones, and severe hypercalciuria.
During pregnancy and lactation, treatment should always be under the direction of a physician. During pregnancy and lactation, requirements for calcium and vitamin D3 are increased, but in deciding on the required supplementation allowances should be given to the availability of these agents from other sources. If calcium and iron supplements are both required to be administered to the patient, they should be taken at different times. Overdoses of vitamin D3 have shown teratogenic effects in pregnant animals. In humans, long-term hypercalcaemia can lead to physical and mental retardation, aortic stenosis, and retinopathy in a newborn child. Vitamin-D 3 and its metabolites pass into the breast milk.
Patients with mild to moderate renal failure or mild hypercalciuria should be supervised carefully. Periodic checks of plasma calcium levels and urinary calcium excretion should be made in patients with mild to moderate renal failure or mild hypercalciuria. Urinary calcium excretion should also be measured. In patients with a history of renal stones, urinary calcium excretion should be measured to exclude hypercalciuria. With long-term treatment, it is advisable to monitor serum and urinary calcium levels and kidney function, and reduce and stop treatment temporarily if urinary calcium exceeds 7.5 mmol/24 hours. Allowances should be made for calcium and vitamin D3 supplements from other sources.
Keep in a dry place away from light and heat. Keep out of the reach of children.
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At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.