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Rovantin 100mg Tablet 1 Strip
Cefpodoxime/Rovantin 100 mg is an antibiotic. It kills the bacteria by preventing them from forming the bacterial protective covering (cell wall) which is needed for them to survive. Cefpodoxime is used for Pharyngitis, Acute otitis media, Community-acquired pneumonia, Sinusitis, UTI, Cystitis, Gonorrhea, Skin and skin structure infections, Tonsillitis, Respiratory tract infections, Acute Maxillary Sinusitis, Acute bacterial exacerbation of chronic bronchitis
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Price: ৳ 132
MRP:
৳
140.9
6%
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✅ Description:
Rovantin is prescribed for infections caused by susceptible microorganisms, including:
- Ear Infections (Acute Otitis Media): Caused by Streptococcus pneumoniae, Streptococcus pyogenes, Haemophilus influenzae, and Moraxella catarrhalis (including beta-lactamase-producing strains).
- Throat Infections (Pharyngitis/Tonsillitis): Due to Streptococcus pyogenes.
- Sinus Infections (Acute Maxillary Sinusitis): Caused by H. influenzae, S. pneumoniae, and M. catarrhalis (including beta-lactamase-producing strains).
- Community-Acquired Pneumonia: Due to S. pneumoniae and H. influenzae (including beta-lactamase-producing strains).
- Chronic Bronchitis Exacerbations: Caused by S. pneumoniae, H. influenzae (non-beta-lactamase-producing strains), and M. catarrhalis.
- Skin & Soft Tissue Infections: Caused by Staphylococcus aureus and Streptococcus pyogenes.
- Urinary Tract Infections (UTIs): Due to E. coli, K. pneumoniae, Proteus mirabilis, and Staphylococcus saprophyticus.
- Uncomplicated Gonorrhea & Rectal Gonococcal Infections in Women: Caused by Neisseria gonorrhoeae (including penicillinase-producing strains).
Note: This medication should only be used as per a registered physician’s advice.
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✔️ Pharmacology
Rovantin contains Cefpodoxime, a third-generation oral cephalosporin with strong resistance to beta-lactamases and effective action against both Gram-positive and Gram-negative bacteria. As a prodrug, it is metabolized into its active form, Cefpodoxime, which works against a broad range of bacteria.
- Excretion: About 29-33% of the drug is excreted unchanged via urine within 12 hours.
- Stability: Highly stable in the presence of β-lactamase enzymes, making it more effective against Gram-positive bacteria than other third-generation cephalosporins.
- Susceptible Organisms: Includes S. aureus, S. saprophyticus, S. pneumoniae, S. pyogenes, E. coli, K. pneumoniae, H. influenzae, M. catarrhalis, N. gonorrhoeae, P. mirabilis, and others.
✔️ Side Effects
Rovantin is well-tolerated but may cause mild side effects, including:
- Common: Diarrhea, nausea, abdominal pain, headache, dizziness, and fungal infections (skin & vaginal).
- Less Common: Chest pain, muscle pain, indigestion, vertigo, and cough.
- Children: Higher likelihood of skin fungal rashes compared to adults.
✔️ For Adults & Adolescents (13+ years):
- Pharyngitis/Tonsillitis: 100 mg every 12 hours for 5–10 days.
- Acute Sinusitis: 200 mg every 12 hours for 10 days.
- Community-Acquired Pneumonia: 200 mg every 12 hours for 14 days.
- Chronic Bronchitis Exacerbation: 200 mg every 12 hours for 10 days.
- Skin Infections: 400 mg every 12 hours for 7–14 days.
- Uncomplicated UTI: 100 mg every 12 hours for 7 days.
- Uncomplicated Gonorrhea & Rectal Gonococcal Infections: Single 200 mg dose.
✔️ For Children (2 months–12 years):
- Acute Otitis Media: 5 mg/kg every 12 hours for 5 days.
- Pharyngitis/Tonsillitis: 5 mg/kg every 12 hours for 5–10 days.
- Acute Sinusitis: 5 mg/kg every 12 hours for 10 days.
✔️ For Patients with Kidney Issues:
- Severe Renal Impairment (Creatinine Clearance <30 ml/min): Dosage interval should be extended to once every 24 hours.
✔️ For Patients with Liver Cirrhosis:
No dosage adjustment is necessary as the pharmacokinetics remain similar to healthy individuals.
✔️ Pregnancy & Lactation
- Pregnancy: Animal studies show no harmful effects, but no well-controlled human studies exist. Use only if necessary.
- Breastfeeding: Since Cefpodoxime is excreted in breast milk, a decision should be made to either discontinue the drug or breastfeed.
✔️ Drug Interactions
- Antacids & H₂ Blockers: Reduce absorption and peak plasma levels by 24–42%, lowering effectiveness.
- Probenecid: Increases Cefpodoxime concentration by reducing renal excretion (31% increase in AUC).
- Nephrotoxic Medications: When taken with other nephrotoxic drugs, kidney function should be closely monitored.
✔️ Contraindications
Patients allergic to Cefpodoxime or cephalosporin antibiotics should avoid using this medication.
✔️ Precautions & Warnings
- Dosage should be adjusted in patients with reduced kidney function.
- Caution is advised when used with potent diuretics, as they may enhance the risk of renal impairment.
- May cause overgrowth of non-susceptible organisms. Regular monitoring is recommended.
✔️ Storage Instructions
- Store in a cool, dry place away from direct light and heat.
- Keep out of children’s reach.
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