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Doxin 50mg Capsule 10pcs
Doxycycline Hydrochloride, the active ingredient in Doxin, is a semi-synthetic tetracycline antibiotic with a broad range of activity. Primarily bacteriostatic, it is particularly effective against Staphylococcus aureus and Nocardia, including penicillin-resistant strains. It is also active against certain Gram-negative bacteria like E. coli, Proteus mirabilis, and Klebsiella, as well as anaerobes like Bacteroides fragilis.
Doxin is a broad-spectrum antibiotic belonging to the tetracycline group. It effectively treats a wide variety of infections caused by Gram-positive and Gram-negative bacteria, spirochetes, mycoplasma, rickettsia, and mycobacteria. It serves as an alternative to penicillin in treating gonorrhea and syphilis by inhibiting bacterial protein synthesis within cells.
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✅ Description:
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✔️ Doxycycline is effective against infections caused by:
- Haemophilus influenzae and H. ducreyi
- Actinomyces, Brucella, and Vibrio cholerae
- Nocardia, Chlamydia, Mycoplasma, and Rickettsiae
- Spirochetes such as Borrelia recurrentis, Treponema pallidum, and Treponema pertenue
- Plasmodium falciparum
✔️ Dosage
- General dosage: 200 mg on the first day, followed by 100 mg daily for 7–10 days.
- Severe infections (e.g., resistant urinary tract infections): 200 mg daily for 10 days.
- Acne: 100 mg daily.
- Uncomplicated genital chlamydia and non-gonococcal urethritis: 100 mg twice daily for 7–21 days (14–21 days for pelvic inflammatory disease).
- Always follow the advice of a registered physician.
✔️ Reported side effects may include:
- Nausea, vomiting, and diarrhea.
- Skin rashes.
- Hemolytic anemia and eosinophilia.
✔️ Administration
Capsules should be swallowed whole with a sufficient amount of fluid during meals, preferably while sitting or standing.
✔️ Drug Interactions
- The absorption of tetracyclines may be reduced by antacids containing aluminum, calcium, or magnesium, as well as iron-containing preparations.
- Bismuth salicylate also reduces the absorption of tetracyclines.
- Barbiturates, carbamazepine, and phenytoin decrease the half-life of doxycycline.
- Concurrent use of tetracyclines may reduce the effectiveness of oral contraceptives.
- Patients on anticoagulant therapy may require a lower dosage of anticoagulants.
- Tetracyclines should not be used alongside penicillin.
✔️ Doxycycline is contraindicated in:
- Patients with a known hypersensitivity to tetracyclines.
- Children under 8 years of age.
- Pregnant women and breastfeeding mothers.
✔️ Pregnancy & Lactation
- Doxycycline is not recommended for pregnant women due to the risk of permanent tooth discoloration and its effects on fetal bone development.
- Doxycycline passes into breast milk, so breastfeeding mothers should avoid using it.
✔️ Precautions & Warnings
- Using tetracyclines during tooth development (the second half of pregnancy, infancy, or childhood up to 8 years) can cause permanent tooth discoloration.
- These drugs are not recommended for children under 8 years of age.
✔️ Storage Conditions
- Keep the medication out of reach of children.
- Store in a cool, dry place away from light.
⚠️Disclaimer:
At ePharma, we’re committed to providing accurate and accessible health information. However, all content is intended for informational purposes only and should not replace medical advice from a qualified physician. Please consult your healthcare provider for personalized guidance. We aim to support, not substitute, the doctor-patient relationship.
