L-Amlo 2.5mg Tablet

✔️ Side Effects

Common side effects may include:

• Difficulty breathing
• Dizziness
• Fast heartbeat (reflex tachycardia)
• Low blood pressure
• Abdominal pain
• Swelling or edema

Less common effects may include:

• Diarrhea
• Back pain
• Headache
• Fatigue
• Nausea

✔️ L-Amlo should be taken orally.

• Usual initial adult dose: 2.5 mg once daily
• Maximum recommended dose: 5 mg once daily
• Elderly patients or those with liver impairment: Treatment may be initiated with 1.25 mg once daily.
• When adjusting the dose, a waiting period of approximately 7–14 days is generally recommended between dose changes, unless faster adjustment is clinically necessary and the patient can be monitored closely.
• Children 6–17 years: The usual effective dose is 1.25–2.5 mg once daily. Doses above 2.5 mg daily have not been adequately studied in this age group.

✔️ Pregnancy & Breastfeeding

Available information from post-marketing reports has not established a clear risk of major birth defects or miscarriage associated with amlodipine use during pregnancy. However, pregnant women should use L-Amlo only after consulting their doctor.

No harmful effects have been observed in breastfed infants exposed to amlodipine, but breastfeeding mothers should discuss its use with their healthcare provider.

✔️ Certain medicines may affect the action or blood levels of L-Amlo:

• CYP3A inhibitors: Medicines that inhibit CYP3A may increase amlodipine exposure and may require dose adjustment.
• CYP3A inducers: Their effect on amlodipine levels is not well established.
• Simvastatin: Amlodipine can increase simvastatin exposure; the simvastatin dose should generally not exceed 20 mg daily when used together.
• Cyclosporine or tacrolimus: Amlodipine may increase their blood concentrations, so regular monitoring may be required.

L-Amlo can be taken with or without food, as food does not significantly affect its absorption. Avoid grapefruit products and natural licorice unless your doctor advises otherwise.

✔️ Contraindications:

L-Amlo should not be used by patients with a known allergy or hypersensitivity to amlodipine or its components.

✔️ Safety Information:

Low Blood Pressure:
L-Amlo can occasionally cause symptomatic hypotension, particularly in people with severe aortic stenosis. Because its action develops gradually, sudden severe hypotension is less likely.

Angina or Heart Attack:
In patients with significant coronary artery disease, angina may occasionally worsen or a heart attack may occur after starting treatment or increasing the dose. Seek medical attention if chest pain becomes more frequent or severe.

Liver Impairment:
Amlodipine is extensively processed by the liver and remains in the body longer in patients with impaired liver function. Therefore, people with severe hepatic impairment should start with a low dose and have their treatment adjusted gradually under medical supervision.

✔️ Storage:

Store L-Amlo in a cool, dry place, protected from light and moisture. Keep the medicine out of the reach of children.