Bisoren 5 Tablet 1 Strip

✔️ Uses of Bisoren 5

• Hypertension (high blood pressure)
• Angina (heart-related chest pain)
• Heart failure

✔️ How does Bisoren 5 work?

Bisoren 5 reduces the contraction of your heart muscles and causes a decrease in heart rate. This makes your heart more efficient at pumping blood throughout the body, thus controlling your blood pressure. 

✔️ Side Effects of Bisoren 5

Possible side effects include gastrointestinal disturbances, bradycardia, hypotension, headache, fatigue, sleep disturbances, dizziness, vertigo, thrombocytopenia, visual disturbances, and alopecia.

✔️ Quick Suggestions:

• Bisoprolol can be taken with or without food. Do not break, crush, or chew the tablet.
• Take it at the same time every day for the ease of remembering.
• Avoid taking more or fewer doses than that prescribed by your doctor.
• Keep taking the medicine regularly even if your condition improves.
• Avoid self-medication or discontinuation of this medicine without your doctor's advice.
• Avoid smoking, eat a healthy balanced diet, and exercise regularly to get the maximum benefit from the treatment. Bisoprolol can make you dizzy.
• Hence, get up slowly when rising from a sitting or lying down position.
• If you experience any side effects that persist or worsen, consult your doctor.

✔️ Hypertension and Angina:

Hypertension (High Blood Pressure):

• Definition: Hypertension occurs when the blood circulating in your vessels exerts elevated pressure on the vessel walls.
• Complications: If left untreated, hypertension can lead to severe complications such as stroke and heart attack.
• Treatment: Bisoprolol is employed in the management of hypertension, helping to regulate blood pressure and reduce the risk of associated complications.

Angina (Chest Pain):

• Definition: Angina manifests as chest pain resulting from a decreased oxygen supply to the heart muscles.
• Mechanism: Bisoprolol is utilized in the treatment of angina by reducing the workload on the heart, and alleviating chest pain associated with decreased oxygen delivery.

✔️ Pharmacology

Bisoprolol hemifumarate, the most selective ß1 blocker, exhibits a high affinity for the ß1 receptor. By blocking the ß1 adrenergic receptor in the heart and vascular smooth muscle, it reduces heart rate, cardiac output, and arterial blood pressure. Unlike some non-ß1 selective ß-blockers, Bisoprolol does not impact lipid metabolism over long-term use.

✔️ Dosage & Administration:

Heart Failure: Initial 1.25 mg daily, increasing weekly to 2.5 mg, 3.75 mg, 5 mg, 7.5 mg, and finally 10 mg if tolerated.

Angina: Typically 10 mg daily (5 mg may suffice), with a maximum of 20 mg per day.

Hypertension: Initiate with 5 mg daily, considering 2.5 mg for some; adjust based on response, with a maximum of 10 mg daily.

✔️ Interaction

Avoid combining Bisoprolol with other ß-blocking agents.

✔️ Contraindications

Do not use in cardiogenic shock, overt heart failure, second or third-degree A-V block, right ventricular failure due to pulmonary hypertension, and sinus bradycardia.

✔️ Pregnancy & Lactation

The safety of Bisoprolol during pregnancy is not established, and data is unavailable for lactation.

✔️ Precautions & Warnings

Regular monitoring of renal, hepatic, and hematopoietic function is advised during long-term use of Bisoprolol.

✔️ Storage Conditions

Store in a dry place, protected from light and heat, and keep out of children's reach.