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Bisoren 2.5 Tablet 1 Strip
đĻ Each tablet contains Bisoprolol Fumarate 5mg or as prescribed
đŠē Therapeutic Class: Selective β1-blocker
đ Manufactured by: Renata Limited
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â Description:
Bisoren 2.5
- High Blood Pressure (Hypertension)
- Chest Pain from Heart Disease (Angina Pectoris)
- Moderate to Severe Heart Failure (with reduced ejection fraction)
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âī¸ Pharmacology Highlights:
- Ultra-selective Ã1-blocker: Bisoprolol offers the highest affinity for Ã1-receptors among beta-blockers.
- Heart-focused action: Reduces heart rate & cardiac workload â lowers blood pressure & anginal symptoms.
- Metabolically neutral: Long-term use does not negatively impact cholesterol, including HDL.
- Once-daily dosing: Thanks to excellent absorption (>90%), minimal first-pass metabolism, and a 10â12 hour half-life.
âī¸ Common Side Effects:
- Fatigue, dizziness, headache
- Gastrointestinal upset: nausea, vomiting, constipation, diarrhea
- Cold hands/feet, muscle cramps
- Respiratory issues in asthma/COPD patients
âī¸ Dosage & Administration:
- Adults: Start with 5 mg once daily. Adjust gradually (up to 20 mg/day max).
- Elderly: Usually no adjustment needed unless impaired liver/kidney function.
- Renal/Hepatic Impairment: Start low (5 mg/day). Titrate cautiously.
- Children: Not established.
đ Dose adjustment interval: 2 weeks
âī¸ Important Interactions:
- Avoid combining with other beta-blockers.
- Caution with clonidine, calcium channel blockers (verapamil, diltiazem), antiarrhythmics, or catecholamine-depleting drugs.
- Monitor for excessive heart suppression or hypotension in combination therapy.
âī¸ Contraindications:
- Cardiogenic shock
- Advanced AV block (2nd/3rd degree)
- Uncontrolled heart failure
- Severe bradycardia or pulmonary hypertension-related RV failure
âī¸ Pregnancy & Lactation:
Pregnancy: Use only if clearly needed. Animal studies show fetal risk at high doses.
Lactation: Unknown if excreted in human milk; breastfeeding should be discontinued if necessary.
âī¸ Precautions:
- Use caution in patients with renal/hepatic impairment
- Patients with a history of severe allergic reactions may have reduced response to epinephrine
- Avoid abrupt withdrawal
âī¸ Storage:
Store in a cool, dry place away from light and heat. Keep out of childrenâs reach.
Disclaimer:
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information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
