Rolac 10mg Tablet is used to treat moderate to severe acute postoperative pain in the short term.
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Rolac 10mg Tablet contains Ketorolac tromethamine, which is a type of painkiller. It is used for the short-term management of sudden and moderately severe pain, typically occurring after surgery or related to musculoskeletal issues. Short-term pain refers to pain that lasts for five days or less and is characterized by its sudden and sharp nature.
It is important to note that Rolac 10mg Tablet is not recommended for use in patients who are already taking other nonsteroidal anti-inflammatory drugs (NSAIDs), such as aspirin, or in individuals with advanced kidney, heart, cerebrovascular, or gastrointestinal diseases, or a tendency to bleed easily. Before taking Rolac 10mg Tablet, it is advisable to inform your doctor if you have liver, lung, or heart diseases, high blood pressure, or inflammatory bowel diseases.
The use of Rolac 10mg Tablet is not recommended during pregnancy, especially during the last three months, and in breastfeeding mothers. It is also not recommended for use in children below 17 years of age. Elderly patients above 65 years of age should use Rolac 10mg Tablet with caution.
It is important to avoid smoking and consuming alcohol while taking Rolac 10mg Tablet. Common side effects of Rolac 10mg Tablet include nausea, indigestion, stomach pain, diarrhea, dizziness, drowsiness, headache, or swelling. If these symptoms worsen or persist, it is advised to consult your doctor immediately.
Avoid consumption of alcohol while taking Rolac 10mg Tablet because you would be more likely to develop stomach problems.
is not recommended in women who are pregnant (especially during the last 3 months) or trying to get pregnant as it may harm the baby. If you are pregnant, think you may be pregnant or are planning for a child, contact your doctor before taking Rolac 10mg Tablet.
Rolac 10mg Tablet is not recommended for use in breastfeeding mothers. Consult your doctor for advice.
Do not drive or operate any machines if you feel dizzy, drowsy, tired, or light-headed after taking Rolac 10mg Tablet.
is not recommended for use in patients with severe kidney disease. Rolac 10mg Tablet should be used with caution in patients with other kidney problems. Consult your doctor for advice.
Dose adjustment may be needed in patients with liver impairment. Please consult your doctor if you have a liver impairment or any concerns regarding this.
Rolac 10mg Tablet works by blocking the effects of prostaglandins, which are substances produced by the body in response to injury or inflammation. Prostaglandins are responsible for causing pain, swelling, and inflammation at the site of injury. By inhibiting the production of prostaglandins, ketorolac reduces pain and inflammation.
Additionally, ketorolac also inhibits the transmission of pain signals between the nerve endings and the brain. This further contributes to its analgesic effects, as it helps to reduce the perception of pain.
By blocking prostaglandins and inhibiting pain signals, the ketorolac tablet provides relief from moderate to severe pain, such as post-operative pain or musculoskeletal pain.
Rolac 10mg Tablet is primarily used for the short-term management of sudden moderate to severe pain, typically after surgical procedures. It is also effective in providing relief from musculoskeletal pain, which includes pain in the muscles, bones, joints, ligaments, or tendons. Rolac 10mg Tablet can help alleviate pain in conditions such as fractures, sprains, strains, and other musculoskeletal injuries. However, it's important to note that ketorolac should be used for a short duration (up to five days) due to its potential side effects on the gastrointestinal system and kidneys.
Ketorolac tromethamine, classified as a non-steroidal anti-inflammatory drug (NSAID), is a powerful analgesic. Its main mechanism of action involves the inhibition of the cyclooxygenase enzyme system, which is responsible for the production of prostaglandins. By inhibiting this enzyme system, ketorolac tromethamine reduces the production of prostaglandins, which are involved in pain and inflammation signaling pathways.
It's important to note that ketorolac tromethamine primarily functions as an analgesic at therapeutic doses, meaning it primarily provides pain relief rather than exerting a significant anti-inflammatory effect. This distinguishes it from other NSAIDs that are commonly used for their anti-inflammatory properties.
Adult Dose:
Oral: For short-term management of moderately severe acute pain that requires opioid-level analgesia, the initial dose is 20 mg taken once after IV or IM therapy. After the initial dose, a maintenance dose of 10 mg can be taken every 4 to 6 hours, not exceeding a total daily dose of 40 mg.
IV: A single dose of 30 mg can be administered or 30 mg every 6 hours, with a maximum daily dose of 120 mg.
IM: A single dose of 60 mg can be administered or 30 mg every 6 hours, with a maximum daily dose of 120 mg.
Elderly: The dosing for elderly patients is reduced compared to adults. For IV and IM administration, the initial dose is 15 mg as a single dose or 15 mg every 6 hours, with a maximum daily dose of 60 mg. For oral administration, the initial dose is 10 mg taken once after IV or IM therapy, followed by a maintenance dose of 10 mg every 4 to 6 hours, not exceeding a total daily dose of 40 mg.
Child Dose:
Children aged 2 to 16 years can receive a single dose of 0.5 mg/kg IV/IM once, not exceeding 15 mg. For multiple doses, the recommended regimen is 0.5 mg/kg IV/IM every 6 hours, not exceeding a duration of 5 days.
Renal Dose:
In patients with severe renal impairment, Ketorol should not be used. For patients with moderate renal impairment (moderately elevated serum creatinine), the dosage should be reduced to 50% of the recommended dosage, not exceeding a total daily dose of 60 mg for IM/IV administration.
It's important to note that this is a paraphrased summary and should not replace the specific instructions and guidance provided by a healthcare professional.
Rolac 10mg Tablet may interact with certain medications such as blood thinners (warfarin, heparin), antipsychotic agents (lithium), pain killers (aspirin), uricosuric medications (probenecid), and anti-progestational steroids (mifepristone). It is important to inform your doctor about any pre-existing medical conditions, including stomach ulcers or perforation, bleeding problems, heart problems, blood circulation problems, asthma, fluid retention, thrombosis, porphyria, anemia, high blood pressure, and kidney or liver problems.
Patients who are hypersensitive to ketorolac or other NSAIDs should avoid using it. It should not be given to youngsters under the age of sixteen. It's also not a good idea to use it as a pre-surgery analgesic.
Ketorolac tromethamine, the active ingredient in Rolac 10, is classified by the US FDA as Pregnancy Category C. This means that it may not be safe for use during pregnancy and lactation unless the potential benefits to the mother outweigh the potential risks to the fetus or breastfeeding infant. It is recommended to consult with a healthcare professional before using this medication during pregnancy or while breastfeeding to assess the individual risks and benefits in your specific situation.
Do not use Rolac 10mg Tablet if:
Keep in a dry place away from light and heat. Keep out of the reach of children.
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