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Todol 10mg Tablet 14pcs
Todol is indicated for:
- Short-term management of moderate to severe acute post-operative pain.
- Ophthalmic use: Relieves pain, inflammation, and light sensitivity following ocular surgery.
- It is also used to decrease eye inflammation or redness caused by seasonal allergies.
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✅ Description:
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✔️ Description:
Todol belongs to the pyrrolo-pyrrole group of nonsteroidal anti-inflammatory drugs (NSAIDs). Chemically, it is known as 5-benzoyle-2,3-dihydro-1H-pyrroligine-1-carboxylic acid, compound with 2-amino-2-(hydroxymethyl)-1,3-propanediol.
- Mechanism of Action: Todol inhibits the cyclooxygenase (COX) enzyme system, which reduces prostaglandin synthesis. This action helps alleviate pain and inflammation but with minimal anti-inflammatory effects at analgesic doses.
- Pharmacokinetics: The drug is highly protein-bound and is metabolized in the liver. Both metabolized products and some unchanged drugs are excreted via urine.
- Biological Activity: The S-form of Todol is responsible for its biological effect. The drug's pharmacokinetic properties are linear.
✔️ Dosage & Administration
- Recommended dose: 10 mg every 4-6 hours.
- Limit use to short-term (up to 7 days); avoid long-term use.
- Do not exceed 40 mg/day.
✔️ Common side effects include:
- Nausea, vomiting
- Gastrointestinal bleeding, peptic ulcer
- Anxiety, drowsiness, headache
- Fatigue, excessive thirst
- Hypertension, chest pain, bradycardia
- Pulmonary edema, infertility in females
✔️ Interactions
- Other NSAIDs or aspirin: Increased side effects of Todol.
- Anti-coagulants: Enhanced anticoagulant effect.
- Beta Blockers: Reduced antihypertensive effect.
- ACE Inhibitors: Increased risk of renal impairment.
- Methotrexate: Enhanced methotrexate toxicity.
✔️ Contraindications
- Hypersensitivity to Ketorolac or other NSAIDs.
- Children under 16 years of age.
- Prophylactic analgesic use before surgery.
✔️ Pregnancy & Lactation
- FDA Pregnancy Category C: Should be avoided during pregnancy and lactation unless benefits outweigh risks.
- Ketorolac may pose risks to the fetus; consult a healthcare professional before use.
✔️ Precautions & Warnings
- Use caution in patients over 65 years of age.
- Patients with active peptic ulcers, gastrointestinal bleeding, asthma, or liver dysfunction should take Todol with caution.
- Eye Drops: Discontinue use if corneal epithelial breakdown occurs. Avoid use while wearing contact lenses.
✔️ Storage Conditions
- Keep in a dry place away from light and heat.
- Keep out of the reach of children.
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information as musch as possible. Although we do not guarantee the
accuracy and the completeness of the information that provided and
here information is for informational purposes only.
The information contained herein should NOT be used as a substitute
for the advice of a qualified physician. This may not cover
everything about particular health conditions,
lab tests, medicines, all possible side effects, drug interactions,
warnings, alerts, etc. Please consult your healthcare professional
and discuss all your queries related to any disease or medicine. We
intend to support, not replace, the doctor-patient relationship.
