Vass 20mg Tablet 10pcs

✔️ Uses of Vass 20mg Tablet

• Hypercholesterolaemia
• Prevention of cardiovascular diseases

✔️ Side Effects of Vass 20mg Tablet

Mostly well-tolerated, common side effects include constipation, flatulence, dyspepsia, stomach discomfort, infection, headache, back pain, rash, asthenia, arthralgia, and myalgia.

✔️ How does Vass 20mg Tablet work?

Atorvastatin, an HMG-CoA reductase inhibitor, selectively inhibits this enzyme, the rate-limiting step in cholesterol production. By reducing cholesterol synthesis in the liver and increasing hepatic LDL receptors, it lowers plasma cholesterol and lipoprotein levels.

✔️ Quick Suggestions:

✔️ Indication of Vass 20mg Tablet

When diet and non-pharmacological methods are insufficient for reducing high total cholesterol, LDL cholesterol, apolipoprotein B (Apo-B), and triglyceride levels in the following conditions, Vass 20 is prescribed as an adjuvant to diet:

1. Lowering total cholesterol and LDL cholesterol in individuals with familial hypercholesterolemia (heterozygous and homozygous).
2. Treating patients with combined dyslipidemia having high cholesterol and triglycerides (Fredrickson Type Ia and Ib).
3. Treating hypertriglyceridemia patients with elevated blood triglyceride levels (Fredrickson Type IV).
4. Treating dysbetalipoproteinemia patients (Fredrickson Type III).

✔️ Pharmacology

• Atorvastatin, the active ingredient in Vass 20mg Tablet, is an HMG-CoA reductase inhibitor.
• It blocks the action of the enzyme HMG-CoA reductase, a key enzyme involved in cholesterol synthesis.
• Inhibition of this enzyme leads to a decrease in the production of cholesterol in the liver.

By inhibiting cholesterol synthesis, Vass 20mg Tablet lowers low-density lipoprotein (LDL) cholesterol levels, often referred to as "bad" cholesterol. Atorvastatin increases the number of LDL receptors on the liver cells, enhancing the removal of LDL cholesterol from the blood. It also reduces triglyceride levels, another type of fat in the blood. Vass 20mg Tablet may increase high-density lipoprotein (HDL) cholesterol, often termed "good" cholesterol.

• By modulating cholesterol levels, Vass 20mg Tablet helps in preventing the accumulation of cholesterol in blood vessels.
• It is effective in lowering the risk of cardiovascular events like heart attack and stroke.

Understanding the mechanism of action provides insights into how Vass 20mg Tablet addresses lipid abnormalities and contributes to cardiovascular health.

✔️ Dosage & Administration of Vass 20mg Tablet

Primary hypercholesterolemia and combined hyperlipidemia:

• Adults: Usually 10 mg once daily; may increase to a max of 80 mg once daily if necessary.
• Children (10-18 years): Initially 10 mg once daily, increased to a usual max of 20 mg once daily.

Familial hypercholesterolemia:

• Adults: Initially 10 mg daily, increased to 40 mg once daily; may further increase to a max of 80 mg once daily.
• Children (10-18 years): Initially 10 mg once daily, increased to a usual max of 80 mg once daily.

Prevention of cardiovascular events:

• Adults: Initially 10 mg once daily, adjusted according to the response.

✔️ Interaction

Concurrent use with certain medications like cyclosporin, fibric acid derivatives, erythromycin, azole antifungals, niacin, antihypertensives, hypoglycemic medications, digoxin, oral contraceptives, colestipol, antacid, or warfarin may affect Atorvastatin. Regular monitoring is essential.

✔️ Contraindications

Avoid in patients hypersensitive to any component of atorvastatin, with active liver disease, unexplained chronic transaminase increases, or a history of severe reactions to HMG-CoA reductase inhibitors.

✔️ Pregnancy & Lactation

Not recommended during pregnancy due to potential risks. Breastfeeding is not advised while taking atorvastatin.

✔️ Precautions & Warnings

Liver function tests should be done before and during therapy, especially in those with alcohol consumption or liver disease history. Discontinue if increased CPK levels or myopathy is detected.

✔️ Storage Conditions

Keep in a dry area, away from light and heat. Keep out of children's reach.

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7. Does Atorvastatin cause memory loss?

• Very rare cases of memory loss were reported.
• Consult your doctor if experienced.

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9. What are the most common side effects?

• Nausea, indigestion, constipation, headache, muscle pain.

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