Nexum Mups | 20mg | Tablet | 10'S | Esomeprazole | Get at ePharma
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Nexum Mups 20mg Tablet

Generic: Esomeprazole

Type: Tablet

Pack Size: 10 Pcs

Nexum Mups 20mg Tablet treats ulcers. Esophagitis, which causes the food pipe to expand, gastroesophageal reflux disease, which occurs when stomach acid rushes back into the food pipe, and other disorders affecting the stomach and intestines are all treated with it. Additionally, it treats acidity brought on by the use of medicines as well as stress ulcers, which are sores that can develop in the stomach and intestine as a result of illnesses, infections, etc. It functions by preventing your stomach's overproduction of acid.


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Discount Price: ৳ 94
MRP: ৳ 100 6% Off

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✅ Description:

  • The proton pump inhibitor medication class, which includes Nexum Mups 20mg Tablet, lowers the quantity of stomach acid produced. It treats Zollinger-Ellison syndrome, stomach ulcers, and gastroesophageal reflux disease (GERD). (overproduction of acid due to pancreatic tumor).
  • By inhibiting the actions of an enzyme (H+/K+ ATPase or gastric proton pump), Nexum Mups 20mg Tablet aid in lowering stomach acid. This proton pump, which is located in the stomach wall cells, is in charge of releasing gastric acid secretion, which damages the duodenum, stomach, and food pipe tissues.
  • Nexum Mups 20mg Tablet reduces the symptoms of gastroesophageal reflux disease (GERD), often known as heartburn, and esophagitis, an inflammation of the lining of the food pipe.
  • Take Nexum Mups 20mg Tablet 1-2 hours before a meal. Depending on your medical condition, you are encouraged to take Nexum Mups 20mg Tablet for as long as your doctor has prescribed it for you.
  • Adults taking Nexum Mups 20mg Tablet may have typical adverse reactions including headache, diarrhea, nausea, stomach discomfort, vomiting, flatulence, dizziness, and arthralgia. (joint pain).
  • Children who use Nexum Mups 20mg Tablet may get upper respiratory infections (URI), headaches, fever, diarrhea, vomiting, rash, and stomach discomfort.  These side effects are transient and may go away with time, but if they continue, see a doctor.

Safety Advices


Alcohol
CAUTION

Alcohol use while taking Nexum Mups 20mg Tablet may result in dehydration and increased stomach acid levels, reducing the effectiveness of the medication. So, try to restrict or avoid drinking alcohol or speak with a doctor before taking Nexum Mups 20mg Tablet 


Pregnancy
CAUTION

There isn't much data to support the safety of Nexum Mups 20mg Tablet during pregnancy, thus it's often not advised. Therefore, consult a physician before using Nexum Mups 20mg Tablet. Before giving you a prescription, your doctor will consider the advantages and any possible hazards


Breastfeeding
CONSULT YOUR DOCTOR

Use of Nexum Mups 20mg Tablet  during nursing is probably not advised. The medication may enter breastmilk and damage the infant, according to limited human evidence.


Driving
CAUTION

Nexum Mups 20mg Tablet may occasionally result in lightheadedness, drowsiness, or blurred vision. If you have these symptoms, wait until you feel better before driving or using heavy equipment.


Kidney
CAUTION

Patients with kidney disease should consult a doctor before taking Nexum Mups 20mg Tablet.


Liver
CAUTION

Nexum Mups 20mg Tablet should be taken with precaution in patients with liver disease.

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✔️ Uses of Nexum Mups 20mg Tablet
  • Hyperacidity
  • Heartburn
  • Stomach Ulcer
  • Zollinger-Ellison syndrome
✔️ How Nexum Mups 20mg Tablet works?

Nexum Mups 20mg Tablet is successful at treating Zollinger-Ellison syndrome, gastroesophageal reflux disease, and erosive esophagitis (inflammation of the food pipe). The proton pump gate is permanently blocked by Nexum Mups 20mg Tablet. (which secretes stomach acid). All age groups, including specific populations like the elderly, pregnant, breastfeeding moms, and renal, and liver disease patients, can receive a prescription for it. For these populations, dose adjustments are typically not necessary.

✔️ Side Effects of Nexum Mups 20mg Tablet
  • Headache
  • Dryness in mouth
  • Nausea
  • Abdominal pain
  • Constipation
  • Vomiting
  • Flatulence
  • Skin rash
  • Difficulty in breathing
  • Swelling of face, lips, eyelids, tongue, hands, and feet
  • Irregular heartbeat
  • Diarrhoea
  • Decreased appetite
  • Dizziness
  • Arthralgia (joint pain)
✔️ Quick Suggestions:
  • Nexum Mups 20mg Tablet is a medication that is well-tolerated and lasts a very long period.
  • Try to elevate your bedhead before you go to sleep so that your head and chest are higher than your feet. Use one elevated block rather than a pile of cushions. This will prevent stomach acid from reentering your food pipe.
  • Do not consume alcohol or smoke cigarettes. Alcohol can increase the amount of stomach acid produced, causing acid reflux and heartburn. On the other hand, nicotine use harms the sphincter, a valve that stops stomach acid from flowing back into the food pipe.
  • If you get a fever, watery diarrhea, or persistent stomach pain, call your doctor right immediately.
  • Use of Nexum Mups 20mg Tablet for an extended period of time may result in weak bones and a lack of minerals like magnesium.
  • As directed by your doctor, get enough calcium and magnesium in your diet or as supplements.
  • If you experience reduced urine, edema (swelling brought on by fluid retention), lower back discomfort, nausea, exhaustion, rash, or fever, call your doctor immediately once. These could be kidney-related symptoms.
✔️ Indications of Nexum Mups 20

A medication called Nexum Mups 20 lowers the amount of acid your stomach produces. Heartburn, acid reflux, and issues with your food pipe are all treated with it. Stomach ulcers can also be prevented and treated with Nexum Mups 20. You must take Nexum Mups 20mg as directed by your physician.

✔️ Pharmacology

A proton pump inhibitor called Nexum MUPS 20 blocks the H+/K+ ATPase in the gastric parietal cell, which reduces the amount of stomach acid produced. Esomeprazole (omeprazole's S-isomer), the first proton pump inhibitor with a single optical isomer, offers better acid control than racemic proton pump inhibitors.

✔️ Dosage & Administration of Nexum Mups 20

Esomeprazole is a proton pump inhibitor (PPI) that reduces the amount of acid produced in the stomach, making it effective for treating acid-related conditions such as erosive esophagitis and gastric ulcers. The dosing for different indications and age groups are as follows:

Adult (≥18 years):

  • Erosive esophagitis: 40 mg once daily for 4 weeks
  • Maintenance of healing of erosive esophagitis: 20 mg once daily
  • Risk reduction in NSAID-associated gastric ulcer: 20 mg once daily for 4-8 weeks
  • Pylori eradication (with amoxicillin and clarithromycin): 20 mg twice daily for 7 days
  • Zollinger-Ellison syndrome and idiopathic hypersecretion: 40-80 mg twice daily

Children and adolescents (12-18 years):

  • Erosive esophagitis: 40 mg once daily for 4 weeks
  • Maintenance of healing of erosive esophagitis: 20 mg once daily
  • Pylori eradication (with amoxicillin and clarithromycin): 20 mg twice daily for 7 days

Children (1-11 years):

  • Erosive esophagitis: Weight <20 kg: 10 mg once daily for 8 weeks. Weight ≥20 kg: 10 mg or 20 mg once daily for 8 weeks
  • Maintenance of healing of erosive esophagitis: 10 mg once daily

It's important to note that the Esomeprazole Mups tablet is not approved for use in children younger than 1 year.

As with all medications, it's important to follow the dosing instructions provided by your healthcare provider and to report any side effects or concerns you may have.

✔️ Interaction

In the liver, esomeprazole is mostly metabolized by CYP2C19 and CYP3A4. In vitro and in vivo studies show that esomeprazole does not appear to inhibit CYPs 1A2, 2A6, 2C9, 2D6, or 3A4. There shouldn't be any clinically relevant interactions between these CYP enzymes and the medications you take. Drug interaction investigations have shown that esomeprazole does not interact clinically with phenytoin, warfarin, quinidine, clarithromycin, or amoxicillin.

Esomeprazole may affect CYP2C19, the enzyme that metabolizes the drug the most. Esomeprazole 30 mg decreased the clearance of diazepam by 45% when combined with the CYP2C19 substrate diazepam. Up to 12 hours after therapy, elevated diazepam plasma levels have been documented. Esomeprazole prevents the production of gastric acid. 

✔️ Contraindications

In patients who have a history of hypersensitivity to any of the formulations, esomeprazole is not recommended.

✔️ Pregnancy & Lactation

Caution is advised by the manufacturer. Esomeprazole or its metabolites are not known to occur in human breast milk.

✔️ Precautions & Warnings
  • If you are allergic to Nexum Mups 20mg Tablet or proton pump inhibitors, suffer from stomach cancer, liver illness, low magnesium levels (osteoporosis), low vitamin B12 levels, are pregnant or trying to get pregnant, or are nursing, you should not use Nexum Mups 20mg Tablet.
  • A blood thinner (warfarin), an antifungal (ketoconazole), an anti-HIV medication (atazanavir, nelfinavir), iron supplements, an antibiotic (ampicillin), and a cancer medication may interact with Nexum Mups 20mg Tablet.
  • If you use Nexum Mups 20mg Tablets, tell your doctor. Long-term use of may lead to magnesium, Vitamin B12, and lupus erythematosus deficiencies.
  • Lupus erythematosus is an inflammatory disorder in which the immune system attacks its own tissues. Consuming Nexum Mups 20mg Tablet may conceal gastric cancer symptoms, therefore if you have any significant stomach discomfort or gastric bleeding (blood in your mucus or stools), call your doctor right once.
  • Children under the age of five should not be provided Nexum Mups 20mg Tablet. Children between the ages of 5 and 16 are typically taken Nexum Mups 20mg Tablet. to address food pipe damage caused by acid. (erosive esophagitis).
✔️ Storage Conditions

Store in a dry location at a temperature of not more than 25°C. Light and dampness should be avoided. Keep out of children's reach.

Frequently Asked Questions (FAQ)

A proton pump inhibitor (PPI), a class of drug, is Nexum Mups 20mg Tablet. In the stomach lining, proton pumps are enzymes that help produce the acid necessary for digestion. Proton pumps are less effective when esomeprazole is used. The amount of acid the stomach produces is reduced as a result.

Long-term use of Nexum Mups 20mg Tablet can cause atrophic gastritis (an inflammation of the stomach cells), a lack of vitamin B12, and brittle bones or osteoporosis. (loss of calcium, magnesium and vitamin D). To manage long-term adverse effects, your doctor may advise calcium, vitamin D, or haemoglobin-enhancing drugs.

It is quite unlikely that accidentally taking one or two more pills would result in any issues. If you believe you may have taken too much and feel tired, hot, or have a rapid pulse, consult your doctor right away.

You may start to feel better within 1 hour after taking Nexum Mups 20mg Tablet.

Nexum Mups 20mg Tablet may remains in your body for an average duration of 9 hours

Nexum Mups 20mg Tablet is not recommended during pregnancy as not enough studies are done to understand its safety and efficacy. Consult your doctor before taking this medicine if you are pregnant.
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Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
ePharma reserves the right to make adjustments to pricing, Products and Service offerings for reasons including, but not limited to, changing market conditions, Product discontinuation, Product unavailability, manufacturer price changes, supplier price changes and errors in advertisements. All orders are subject to Product availability and the availability of Personnel to perform the Services. Therefore, Seller cannot guarantee that it will be able to fulfill Customer’s orders. If Services are being performed on a time and materials basis, any estimates provided by Seller are for planning purposes only.

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