Itopri 50 Tablet

✔️ Itopride Hydrochloride

Itopri Tablet is a gastrointestinal medicine used to relieve symptoms associated with chronic gastritis and impaired gastric motility. It may help improve symptoms such as abdominal fullness or bloating, upper abdominal discomfort, loss of appetite, heartburn, nausea, and vomiting.

✔️ Dosage and Administration

The usual adult dose is:

50 mg orally three times daily, preferably before meals.

The dosage may be adjusted according to the patient's age, symptoms, and response to treatment.

Elderly Patients

Older adults may be more susceptible to adverse effects because of age-related physiological changes. They should therefore be monitored carefully. If significant side effects occur, the doctor may reduce the dose or discontinue treatment.

Children and Adolescents

The safety and effectiveness of itopride have not been adequately established in patients below 18 years of age. Therefore, its use in children and adolescents is generally not recommended.

✔️ Important Safety Information

Allergic and Anaphylactoid Reactions

Rarely, serious allergic or anaphylactoid reactions may occur. Treatment should be stopped, and appropriate medical attention sought if symptoms such as:

• Low blood pressure
• Difficulty breathing
• Swelling of the throat or larynx
• Hives
• Pale skin
• Excessive sweating

develop during treatment.

Liver Problems

Liver dysfunction or jaundice may occur in rare cases and may be associated with elevated liver enzymes such as AST, ALT, or GGT. Treatment should be discontinued and medical evaluation obtained if signs of liver problems develop.

✔️ Interaction

Itopri should be used cautiously with medicines that have anticholinergic effects, such as:

• Tiquizium bromide
• Scopolamine butylbromide
• Timepidium bromide
• Other anticholinergic medicines

These medicines can reduce gastrointestinal movement and may therefore decrease the prokinetic effect of itopride.

Always inform your doctor about all prescription medicines, over-the-counter products, and supplements you are taking.

✔️ Itopri should not be used in patients with:

• Known hypersensitivity to itopride or any component of the formulation
• Conditions in which increased gastrointestinal motility could be harmful

This includes situations such as:

• Gastrointestinal bleeding
• Mechanical intestinal obstruction
• Gastrointestinal perforation

✔️ Precautions and Warnings

Itopri increases the activity of acetylcholine and should therefore be used cautiously in susceptible patients.

If gastrointestinal symptoms do not improve, prolonged continuous use without medical reassessment should be avoided.

For tablets supplied in a press-through package (PTP), remove the tablet from the blister before swallowing. The blister sheet itself should never be swallowed because its sharp edges may injure the esophagus or gastrointestinal tract and can potentially cause serious complications.

✔️ Pregnancy and Breastfeeding

The safety of itopride during pregnancy has not been fully established. It should only be considered during pregnancy when the expected therapeutic benefit clearly outweighs the potential risk.

There is limited information regarding the excretion of itopride into human breast milk. Because sufficient clinical experience is lacking, its use during breastfeeding is generally not recommended unless specifically advised by a healthcare professional.

✔️ Storage:

• Store below 30°C.
• Keep in a cool, dry place.
• Protect from direct light.
• Keep all medicines out of the reach of children.