Itopa 50

✔️ How Itopa-50 Works

Itopride Hydrochloride works through two complementary mechanisms. It blocks dopamine D2 receptors and inhibits acetylcholinesterase, which increases the availability of acetylcholine in the gastrointestinal tract.

The increased acetylcholine enhances gastrointestinal contractions, increases lower esophageal sphincter pressure, promotes stomach movement, accelerates gastric emptying, and improves coordination between the stomach and duodenum.

✔️ Interaction

Itopa-50 may interact with medicines that have anticholinergic effects, such as:

• Tiquizium bromide
• Scopolamine butyl bromide
• Timepidium bromide
• Other anticholinergic medicines

These medicines may reduce the gastrointestinal motility-enhancing effect of itopride because they oppose acetylcholine-mediated activity in the digestive tract.

Tell your doctor or pharmacist about all medicines, supplements, and herbal products you are taking before starting Itopa-50.

✔️ Side Effects:

• Abdominal discomfort
• Nausea
• Diarrhoea or constipation
• Headache or dizziness
• Increased salivation
• Skin rash or itching

✔️ Itopa-50 should not be used in patients who:

• Are allergic or hypersensitive to itopride or any component of the formulation
• Have gastrointestinal bleeding
• Have mechanical intestinal or gastrointestinal obstruction
• Have gastrointestinal perforation

✔️ How to Take Itopa-50

Take Itopa-50 exactly as prescribed by your doctor. It is preferably taken before meals. Do not take it continuously for a prolonged period if your symptoms do not improve without consulting your doctor.

If the medicine is supplied in a press-through blister package, remove the tablet completely from the packaging before swallowing. Never swallow the blister or any part of it.

✔️ Pregnancy & Lactation

The safety of itopride during pregnancy has not been firmly established. It should only be used during pregnancy when the expected therapeutic benefit clearly outweighs the potential risks and when recommended by a doctor.

There is insufficient information regarding the presence and effects of itopride in human breast milk. Therefore, its use during breastfeeding is generally not recommended unless specifically advised by a healthcare professional.

✔️ Safety Information:

Itopa-50 enhances the action of acetylcholine and should therefore be used carefully in patients who may be particularly sensitive to cholinergic effects.

If gastrointestinal symptoms do not improve with treatment, do not continue taking the medicine for an extended period without medical evaluation.

Patients who develop symptoms suggestive of liver dysfunction or jaundice should discontinue the medicine and seek medical advice as directed by their doctor.

✔️ Storage:

Store below 30°C in a cool, dry place away from direct light and moisture. Keep the medicine out of the reach of children.