Esotid HP Kit

Indication

Esotid HP is a medication that combines two antibiotics and an antacid to treat peptic ulcer disease caused by H. pylori bacterial infection. To treat the infection, it fights the bacteria. It also alleviates acidity and pain caused by the infection. Esotid HP is a prescription-only medication. It is recommended that you take it exactly as prescribed.

Pharmacology

Esotid HP is a combination of three antibiotics: amoxycillin, clarithromycin, and esomeprazole that treats bacterial ulcers in the stomach and intestine. Amoxycillin is an antibiotic that prevents the formation of the bacterial protective covering, which is required for bacteria to survive in the human body. Clarithromycin is another antibiotic that inhibits bacterial growth by preventing the synthesis of essential proteins that bacteria require to carry out vital functions. They effectively eliminate your infection when used together. Esomeprazole is a proton pump inhibitor (PPI) that reduces stomach acid and relieves acid-related indigestion and heartburn.

Dosage 

• Nexpro HP Combipack is a three-drug combination that treats stomach/intestinal ulcers by killing the causative bacteria.
• Even if you begin to feel better, finish the prescribed course of medicine. Stopping it too soon may make the ulcer more difficult to treat.
• If you develop an itchy rash, swelling of the face, throat, or tongue, or breathing difficulties while taking Nexpro HP Combipack, stop taking it immediately and notify your doctor.
   

Administration

Check the label before use. Take this medicine in the dose and duration as advised by your doctor.

Interaction

Digoxin-induced cardiotoxicity is more likely. Diuretics increase the risk of hypomagnesemia. Warfarin may cause an increase in INR and prothrombin time. Tacrolimus, saquinavir, and methotrexate serum concentrations may be increased. Drugs metabolized by CYP2C19 may be eliminated more slowly (e.g. diazepam). Ketoconazole, erlotinib, and Fe salts' bioavailability may be reduced. Possibly fatal: Rilpivirine, atazanavir, and nelfinavir serum concentrations and pharmacological effects may be reduced. Clopidogrel's antiplatelet effects may be reduced.

Contraindications

Esomeprazole is not recommended for patients who have a history of hypersensitivity to any component of the formulation or substituted Benzimidazoles.

Side Effects

The most common side effects associated with Esomeprazole include  

• Dizziness
• Dryness in mouth
• Headache
• Nausea
• Abdominal pain
• Constipation
• Flatulence
• Diarrhea.

There is no difference in the types of associated adverse events seen after maintenance treatment for up to 12 months vs short-term treatment.

Pregnancy & Lactation

In pregnant women, there are no appropriate and well-controlled trials. Teratogenic effects have not been discovered in animal investigations. Esomeprazole excretion in milk has not been examined. If the use of esomeprazole is deemed necessary, breastfeeding should be stopped.

Precautions & Warnings

In general, symptomatic response to esomeprazole treatment does not rule out stomach cancer.

According to the manufacturer's instructions, esomeprazole pills should be taken at least one hour before meals. If a patient has difficulty swallowing capsules, place one spoonful of applesauce in an empty bowl, open the Esomeprazole capsules, and carefully pour the pellets within the capsule into the applesauce. The pellets should be mixed with the applesauce and consumed quickly. The applesauce should be cold and mushy enough that it can be eaten without chewing. It is not advised to consume or crush the pellets. The pellet/applesauce mixture should not be refrigerated for future use. Antacids may be used while taking esomeprazole.

Storage Conditions

Store in a dry location at a temperature not exceeding 30°C. Keep out of direct sunlight and dampness. Keep out of children's reach.