Esonix Mups 20mg Tablet

Uses of Esonix Mups 20mg Tablet

Esonix Mups 20mg Tablet is a proton pump inhibitor used for various gastric issues.

How does Esonix Mups 20mg Tablet work?

Proton pump inhibitor (PPI) that reduces stomach acid by inhibiting H+/K+ ATPase.

Side Effects of Esonix Mups 20mg Tablet

• Headache
• Dizziness
• Dryness in the mouth
• Nausea
• Abdominal pain
• Constipation
• Flatulence
• Diarrhea

Quick Suggestions:

• Avoid late-night or bedtime eating.
• Inform the doctor if watery diarrhea, fever, or persistent stomach pain occurs.
• Long-term use may impact bone health; ensure adequate calcium and magnesium intake.
• It should be taken as prescribed, with precautions for prolonged use and potential interactions.
• Regular monitoring and adherence to recommended lifestyle changes enhance its effectiveness.

Indication

Esonix Mups 20mg Tablet is used for the treatment of acid reflux disease, stomach and intestinal ulcers, and Zollinger-Ellison syndrome.

Pharmacology

• MUPS (Multiple-Unit Pellet Framework) refers to tablets compressed from modified-release coated multiparticulates.
• Clinical advantages include greater bioavailability, uniform emptying of pellets from the stomach into the small intestine, and rapid dissolution of enteric coating, resulting in early Tmax and Cmax.
• Combination of quick and sustained action, uniform drug release, once-daily dosing, and reduced risk of localized irritation.

Dosage & Administration of Esonix Mups 20mg Tablet

• Adults:
  • GERD: 20 mg once daily for 4 weeks.
  • Gastric ulcer: 20 mg once daily (4-8 weeks); severe cases may require twice daily.
  • Duodenal ulcer: 20 mg once daily (2-4 weeks); severe cases may require twice daily.
  • NSAID-induced ulceration: 20 mg once daily (4-8 weeks).
  • Reflux esophagitis: 20 mg once daily (4-8 weeks); severe cases may require twice daily.
  • H. pylori eradication: 20 mg twice daily (1 week) with Amoxicillin and Clarithromycin or Metronidazole.
  • Zollinger-Ellison Syndrome: 60 mg once daily; usual maintenance 20-120 mg daily.
• Children (over 2 years old):
  • GERD (Acid regurgitation): 20 mg once daily (2-4 weeks).
  • Reflux esophagitis: 20 mg once daily (4-8 weeks).
• Take as prescribed by the doctor.
• Administered about an hour before a meal.
• Duration depends on the condition; use the lowest effective dose.

Interaction

Potential interactions with CYP2C19-metabolized medicines should be considered when starting or stopping Omeprazole. 

Contraindications

Not recommended for patients with a history of hypersensitivity to any of the formulation ingredients.

Pregnancy & Lactation

• No evidence of harm during pregnancy. Safe to take while pregnant.
• Excreted in breast milk, but therapeutic doses are unlikely to affect the child.

Precautions & Warnings

Use with caution in severe liver dysfunction and renal impairment.

Storage Conditions

Store below 30°C, protect from light and moisture and keep out of children's reach.