Generic Name: Paracetamol 665mg
Company Name Opsonin Pharma Ltd.
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Indications
Renova XR is a medication used to treat pain and fever. It is used to treat a variety of ailments, including headaches, body aches, toothaches, and the common cold. Renova XR can be used alone or in combination with other medications. You should take it on a regular basis, as directed by your doctor. It is usually best taken with food to avoid stomach upset. Take no more or use it for any longer than recommended.
Pharmacology
Renova XR has analgesic, antipyretic, and anti-inflammatory properties. Napa (Acetaminophen) is thought to act primarily in the CNS by inhibiting both isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis. Renova XR is a para aminophenol derivative with analgesic, antipyretic, and anti-inflammatory properties. Renova XR is a popular, safe, and fast-acting analgesic. It is well tolerated and has no aspirin-related side effects.
Dosage and Administration
Adults should take 1-2 tablets every 4 to 6 hours, up to a maximum of 4 gm (8 tablets) per day.
Children (6-12 years): 12 to 1 tablet three to four times per day. It is best not to go above 2.6 gm/day for long-term treatment.
Interaction
Patients who have taken barbiturates, tricyclic antidepressants, and alcohol may show diminished ability to metabolize large doses of Napa. Alcohol can increase the hepatotoxicity of Renova XR overdosage. Chronic ingestion of anticonvulsants or oral steroid contraceptives induces liver enzymes and may prevent attainment of therapeutic Renova XR levels by increasing first-pass metabolism or clearance.
Contraindications
It is contraindicated in known hypersensitivity to Renova XR.
Side Effects
Side effects of Renova XR are usually mild, though hematological reactions including thrombocytopenia, leucopenia, pancytopenia, neutropenia, and agranulocytosis have been reported. Pancreatitis, skin rashes, and other allergic reactions occur occasionally.
Pregnancy & Lactation
Pregnancy category B according to USFDA. This drug should be used during pregnancy only if clearly needed.
Precautions & Warnings
Renova XR should be given with caution to patients with impaired kidney or liver function. Renova XR should be given care to patients taking other drugs that affect the liver.
Storage Conditions
Keep in a dry place away from light and heat. Keep out of the reach of children