Terbin 250mg Tablet 10pcs

✔️ Uses of Terbin 250mg Tablet

• Treats fungal infections of the skin, hair, and nails

✔️ How does Terbin 250mg Tablet work?

is an antifungal medication. It effectively controls fungal infections within the body. It disrupts the fungal cell membrane by blocking the production of certain chemicals (ergosterol) within the cell which is required for its survival. As a result, it stops the fungal cell from multiplication, thereby preventing the further spread of infection.

✔️ Side Effects of Terbin 250mg Tablet

• Diarrhea
• Indigestion
• Stomach pain
• Headache
• Taste disturbance
• Nausea
• Flatulence (gas) 

✔️ Quick Suggestions:

• Terbin 250mg Tablet helps treat skin infections caused by many different types of fungi.
• Finish the full course of treatment even if you feel better.
• It can take a few weeks for the infection to clear and a few months before the skin returns to its normal color.
• Apply an amount sufficient to cover the affected area and 1 inch of the immediate surrounding skin.
• It can make your skin more sensitive to the sun. Use broad-spectrum sunscreen and protective clothing when outdoors.
• Avoid getting in the eyes, nose, or mouth. If accidental exposure occurs, rinse immediately with plenty of water.
• Inform your doctor if the infection has not cleared up after four weeks of treatment.

✔️ Indication of Terbin 250mg Tablet

belongs to a class of drugs called antifungals. Tablets are used to treat fungal infections of toenails and fingernails.

✔️ Pharmacology

Terbinafine, an allylamine antifungal agent, inhibits the biosynthesis of ergosterol (an essential component of fungal cell membranes) by inhibiting the enzyme squalene epoxidase. This leads to the death of fungal cells primarily due to increased membrane permeability mediated by the accumulation of high concentrations of squalene, but not due to ergosterol deficiency. Depending on the concentration of the drug and the fungal species tested in vitro, terbinafine hydrochloride can kill the fungus. However, the clinical significance of the in vitro data is unknown. Terbinafine has been shown to be active against most strains of the following microorganisms, both in vitro and in clinical infections: Trichophyton Mentagrophyte, and Trichophyton Rubrum.

✔️ Dosage & Administration of Terbin 250mg Tablet

Terbinafine tablet:

• For the treatment of fingernail onychomycosis: Terbinafine 250 mg (one tablet), once daily for 6 weeks.
• For the treatment of toenail onychomycosis: Terbinafine 250 mg (one tablet), once daily for 12 weeks.
• The optimal clinical effect is seen some months after mycological cure and cessation of treatment. This is related to the period required for the outgrowth of healthy nails.

Take it with or without food as advised by the doctor. Swallow the whole tablet with a glass of water. Do not break, crush or chew it.

✔️ Interaction

Studies have demonstrated that terbinafine acts as an inhibitor of the CYP450 2D6 isoenzyme in vivo. Drugs that are primarily metabolized by the CYP450 2D6 isoenzyme include tricyclic antidepressants, selective serotonin reuptake inhibitors, beta-receptor blockers, class 1C antiarrhythmic drugs (such as flecainide and propafenone), and monoamine oxidase type inhibitors.

When terbinafine is co-administered with these drugs, close monitoring is recommended, and the dosage of the CYP450 2D6 metabolized drugs may need to be adjusted or reduced.

It is important to consult with a healthcare professional or pharmacist to assess the potential drug interactions and determine the appropriate management when taking terbinafine alongside medications metabolized by the CYP450 2D6 isoenzyme.

✔️ Contraindications

Terbinafine tablets and creams are contraindicated in people allergic to terbinafine.

✔️ Pregnancy & Lactation

There are no adequate and well-controlled studies in pregnant women. Because animal reproduction studies are not always predictive of human response and treatment of nail fungus may be delayed until late in pregnancy, terbinafine should not be started during pregnancy. pregnant. After oral administration, terbinafine is present in the breast milk of nursing mothers. Treatment with terbinafine is not recommended for nursing mothers.

✔️ Precautions & Warnings

• If you have a known allergy to terbinafine, it is important to avoid taking Terbin 250mg Tablet. For pregnant women or nursing mothers, it is recommended to consult with a doctor before using Terbin 250mg Tablet.
• While using Terbin 250mg Tablet, it is advisable to avoid excessive sun exposure as it can increase skin sensitivity to sunlight. It is recommended to wear protective clothing and apply sunscreen when going outside to prevent sunburn.
• If you have conditions such as lupus (an autoimmune disease), a weakened immune system, or kidney and liver problems, it is essential to inform your doctor before taking Terbin 250mg Tablet.
• In case you experience depressive symptoms such as feelings of worthlessness or sadness, loss of interest or energy, mood changes, restlessness, or changes in sleep patterns, it is important to inform your doctor immediately.
• Please consult with a healthcare professional for personalized advice and guidance regarding the use of Terbin 250mg Tablet based on your specific circumstances.

✔️ Storage Conditions

Protect from light and store in a cool, dry area below 30°C.