Nortin 25mg Capsule 10pcs

Uses of Nortin 25mg Capsule

• Neuropathic pain
• Night time bedwetting
• Depression
• Chronic Fatigue Syndrome

Side Effects of Nortin 25mg Capsule

• Dizziness
• Blurred vision
• Decreased urine output
• Weakness in arms, hands, legs, or feet
• Agitation
• Decreased interest in sexual intercourse
• Black tongue
• Breast enlargement
• Dry mouth
• Skin rash

Mechanism of Action:

Nortriptyline is a tricyclic antidepressant and the primary active metabolite of amitriptyline. Its mechanism of action involves modulation of neurotransmitter levels in the central nervous system, particularly serotonin and norepinephrine.

• Neuronal Reuptake Inhibition: Nortriptyline works by inhibiting the reuptake of neurotransmitters, specifically serotonin and norepinephrine, into the nerve endings. This leads to an increased concentration of these neurotransmitters in the synaptic cleft.
• Enhanced Synaptic Concentration: By blocking the reuptake process, nortriptyline prolongs the presence of serotonin and norepinephrine in the synaptic cleft. This enhanced concentration allows for more efficient neurotransmission and communication between neurons.
• Serotonin and Norepinephrine Effects: Increased levels of serotonin and norepinephrine in the synaptic cleft contribute to mood stabilization and regulation. These neurotransmitters play crucial roles in the emotional and physiological aspects of mood, including feelings of well-being and happiness.
• Treatment of Depression: The modulation of serotonin and norepinephrine levels is believed to alleviate symptoms of depression. Depression is often associated with imbalances in these neurotransmitters, and the reuptake inhibition by nortriptyline helps restore a more balanced state.

Nortriptyline's mechanism of action involves blocking the reuptake of serotonin and norepinephrine, leading to increased concentrations of these neurotransmitters in the synaptic cleft. This modulation is essential for the antidepressant effects of nortriptyline and its role in the treatment of depression.

General Instructions:

• Take Nortin 25mg Capsule as instructed by the doctor.
• Follow labeled instructions and prescribed duration.
• Do not stop abruptly; withdrawal symptoms may occur.
• Consult your doctor before making any changes.

Usage of Nortin 25mg Capsule

• Depression: Adult: 75-100 mg/day in divided doses. Max: 150 mg/day in severe depression. Elderly: 30-50 mg/day.
• Bed-wetting (Nocturnal Enuresis): Child: 6-7 yr (20-25 kg): 10 mg; 8-11 yr (25-35kg): 10-20 mg; >11 yr (35-54 kg): 25-35 mg.

Stop taking Nortin 25mg Capsule

The mentioned side effects associated with Nortin 25mg Capsule are serious and require immediate medical attention. If you experience any of the following, stop taking the medication and contact your doctor promptly:

Severe Allergic Reaction:

• Sudden wheeziness
• Trouble breathing
• Swelling of the eyelids, face, or lips
• Rash or itching, especially affecting your entire body

Signs of Heart Attack:

• Sudden chest pain spreading to the neck or arm
• Breathlessness
• Clammy feeling

Signs of Stroke:

• Sudden collapse
• Numbness or weakness in the hands or legs
• Headache
• Dizziness and confusion
• Trouble in vision and swallowing
• Slurred, mixed up, or loss of speech

Liver Inflammation:

• Yellowish skin or whites of your eyes (jaundice)
• Dark urine
• Pale stools
• Tiredness
• Fever
• Nausea
• Weakness
• Drowsiness
• Stomach pain

Suicidal Thoughts:

• Thoughts of harming or killing yourself

Paralyzed Intestine:

• Constant constipation with a swollen stomach
• Fever
• Vomiting

Effects on Blood or Bone Marrow:

• Reduction in the number of red cells, white cells, and platelets
• Bruising
• Bleeding
• Pallor
• Persistent sore throat and fever

Directions for Use of Nortin 25mg Capsule

• Take Nortin 25mg Capsule orally, with or without meals.
• Consume Nortin 25mg Capsule whole with a glass of water or as your doctor suggests.
• Do not crush or chew the Tablet.

Missed Dose of Nortin 25mg Capsule

• Take the missed dose as soon as you remember. Skip if it's almost time for the next dose.

Overdose of Nortin 25mg Capsule

• Contact your doctor immediately if an overdose is suspected. Symptoms may include changes in pulse rates, severe drowsiness, confusion, vomiting, hallucinations, convulsions, and fainting.

Interactions:

Alcohol Interaction:

• Avoid alcohol consumption while taking this medicine.

Interaction with Medicine:

• Glimepiride
• Linezolid
• Ondansetron
• Metoprolol

Disease Interactions:

• Heart Disease: Caution in patients with heart diseases.
• Pheochromocytoma: Extreme caution in patients with Pheochromocytoma.
• Seizure Disorders: Caution in patients with a seizure disorder.
• Diabetes Mellitus: Caution in patients with diabetes.

Contraindications:

• Mania, recent MI, arrhythmias, severe liver disease, children <6 yr.

General Warnings:

• Sedation: May cause moderate to severe sedation. Avoid activities requiring high mental alertness.
• Suicidal Tendencies: May provoke suicidal thoughts, especially in young patients. Report any such incidence to the doctor.
• Withdrawal Symptoms: Do not discontinue abruptly. Consult your doctor before stopping.
• Surgery: Not recommended if planning to undergo surgery in the near future.
• Bipolar Disorder: Not recommended in patients with bipolar disorder.
• Liver Disease: Use with caution in patients with liver disease.

Onset of Action:

The effect of this medicine can be observed in 1 to 3 weeks.

Duration of Effects:

The time until which this medicine remains active in the body is not clinically established.

Heart Attack Recovery:

Not recommended if the patient is recovering from a recent heart attack.

Habit Forming:

No habit-forming tendency has been reported.

Storage Conditions

Store Nortin 25mg Capsule at room temperature since it includes salts. Storing it at temperatures above or below will result in an ineffective effect. Keep out of reach of children and pets