Tigel 60 Tablet

✔️ Side Effects | Tigel 60

• Bleeding
• Shortness Of Breath
• Nosebleed
• Cough
• Low Blood Pressure
• Swelling In The Feet And Ankles
• Back Pain

✔️ Dosage & Administration of Tigel 60

Dosage & Administration:

• Initial (Loading Dose): After an ACS event, a single dose of 180 mg orally (taken as two 90 mg tablets).
• Maintenance Dose (First Year after ACS): 90 mg twice daily (BID).
• Maintenance Dose (After 1 Year of MI): 60 mg twice daily (BID).

Co-administration with Aspirin:

• Start with an initial aspirin loading dose of 325 mg.
• Continue with a maintenance dose of 75–100 mg daily.
• Do not exceed 100 mg/day of aspirin while using this medicine.

Dose Adjustment:

• Renal Impairment: No dose adjustment is required.
• Hepatic Impairment: Use is contraindicated in patients with moderate to severe liver impairment.

✔️ Directions for Use:

• Tigel 60 can be taken with or without food, as advised by your doctor.
• Follow your doctor's instructions on the dosage and timing of this medication.
• Swallow Tigel 60 as a whole with a glass of water.
• Do not crush, break, or chew it.

✔️ Benefits:

• Tigel 60  lowers the risk of heart attacks, strokes, and cardiovascular death in patients with a prior history of heart attack or who have blocked arteries.
• It helps prevent the formation of harmful blood clots, especially in patients with coronary artery disease (CAD) who have undergone stent placement.
• Tigel 60 also reduces the risk of a first heart attack or stroke in individuals with reduced blood flow to the heart (stable coronary artery disease).
• It decreases the risk of stroke and death in adults with narrowed or blocked arteries supplying blood to the brain.
• Tigel 60 is usually prescribed along with low-dose aspirin for better prevention of clot-related events.

✔️ Interaction

Aminocaproic acid, tranexamic acid, and/or recombinant clotting factor VIIa may help enhance haemostasis. Concomitant use with NSAIDs, oral anticoagulants, or fibrinolytic agents should be approached with caution. Certain drugs such as ketoconazole, clarithromycin, nefazodone, ritonavir, atazanavir, rifampicin, dexamethasone, phenytoin, carbamazepine, phenobarbital, simvastatin (doses above 40 mg), and digoxin may interact with this therapy. Additionally, co-administration with cyclosporine can lead to increased peak plasma concentration (Cmax) and overall drug exposure (AUC).

✔️ Warnings:

• Do not take Tigel 60 if you are allergic to any of its components or have a history of bleeding in the brain.
• Inform your doctor if you have/had bleeding problems, serious injury or surgery, stomach ulcers, colon polyps, asthma, COPD (chronic obstructive pulmonary disease), liver problems, stroke, or are due to undergo any surgery.
• Consult your doctor if you are pregnant or plan to become pregnant. Your doctor will decide if it is safe to use Tigel 60 during pregnancy or not.
• Tigel 60 is not recommended during breastfeeding as it passes into the breast milk. Your doctor will decide if you will take Tigel 60 or breastfeed.
• The safety and effectiveness in children below 18 years of age have not been established, so Tigel 60 should not be given to children.
• Seek immediate medical attention if you notice signs of bleeding, such as uncontrollable bleeding, severe bleeding, pink/red/brown urine, vomit that looks like coffee grounds, blood in vomit, red/black stools, or coughing up blood.
• Tigel 60 may cause shortness of breath. Call your doctor if you experience new or unexpected shortness of breath at rest, at night, or during any activity.

✔️ Storage:

Store in a cool and dry place away from sunlight