Tuspel Syrup

Uses of Tuspel Syrup

Fast effective relief of Chest congestion, Cough & Sore throat

How does Tuspel Syrup work?

Tuspel Syrup is a combination of 3 medicines:  Dextromethorphan, Guaifenesin, and Menthol. It is used in the treatment of cough. Dextromethorphan acts on the cough center in the brain and blocks the nerve signals that cause cough. Guaifenesin helps in the removal of mucus (phlegm) from the airways. Menthol provides a cooling sensation and relieves throat irritation.  Thus, together Guaifenesin+Dextromethorphan+Menthol helps to relieve overall cough, cold, and allergic symptoms.

Side Effects of Tuspel Syrup

• Nausea
• Stomach pain
• Diarrhea
• Upset stomach
• Vomiting
• Headache
• Insomnia (difficulty in sleeping)
• Rash
• Sleepiness

Quick Suggestions:

• Tuspel Syrup is prescribed to get relief from cough.
• Drink warm water to help loosen the congestion and lubricate your throat while you are taking this medication.
• Take exactly as directed by your doctor or on the label. Do not increase the dosage or take longer than is recommended.
• In general, most coughs do not last more than 2-3 weeks. If your cough does last longer than this then it's better to see your doctor.
• Inform your doctor if you have a history of stomach ulcers or asthma.
• Inform your doctor if you are taking any other medications, e.g., anti-depressants.
• Avoid dairy products such as milk as it may increase mucus production.
• Drink plenty of fluids to avoid dry throat while you have a cough and loosen mucus.
• You are recommended to inform your doctor that you are taking Tuspel Syrup before undergoing any medical tests or surgery.
• It is advised to stop the use of Tuspel Syrup if your cough persists for more than 1 week and it reoccurs or is accompanied by hay fever, skin rash, or persistent fever. In such cases, consult a doctor immediately.
• Children under the age of 12 should not use this product.

Indication

When it comes to treating chest congestion, cough, and sore throat, there are several options that can provide quick and effective relief. Here are some suggestions:

Stay hydrated: Drink plenty of fluids, such as water, herbal tea, or warm liquids like chicken soup. Hydration helps to thin mucus and soothe a sore throat.

Use a humidifier: Adding moisture to the air can help alleviate chest congestion and soothe a sore throat. Consider using a humidifier or taking a hot shower to breathe in the steam.

Over-the-counter medications: Non-prescription medications can provide relief from symptoms. Options include:

• Expectorants: These help to thin and loosen mucus, making it easier to expel. Look for products containing guaifenesin.
• Cough suppressants: These can help suppress a persistent cough. Dextromethorphan is a common ingredient found in cough suppressant medications.
• Sore throat lozenges or sprays: These can provide temporary relief by numbing the throat and reducing pain. Look for products containing ingredients like benzocaine or menthol.

Saltwater gargles: Mix half a teaspoon of salt in a glass of warm water and gargle the solution. This can help reduce throat inflammation and soothe discomfort.

Honey: Consuming honey, either on its own or mixed with warm water or herbal tea, can help soothe a sore throat. It has natural antibacterial properties and can provide temporary relief.

Rest and self-care: Getting plenty of rest allows your body to recover and heal. Avoid irritants like smoking or exposure to pollutants, which can aggravate symptoms.

Seek medical advice: If your symptoms persist for more than a few days, worsen, or are accompanied by high fever, difficulty breathing, or severe pain, it is advisable to consult a healthcare professional for a proper diagnosis and further guidance.

Remember to read and follow the instructions on any medication you take, and consult a healthcare professional or pharmacist if you have any concerns or questions about specific treatments or their suitability for your condition.

Pharmacology

Guaifenesin acts as an expectorant, which means it helps to loosen thin mucus in the airways, making it easier to cough up and clear chest and throat congestion.

Dextromethorphan hydrobromide is a cough suppressant that works by acting on the brain to reduce the urge to cough. It helps provide relief from coughing by suppressing the cough reflex.

Menthol, which can be derived naturally from plants like peppermint or synthesized, has local anesthetic and anti-irritant properties. It is often used in cough and cold medications to provide a cooling sensation and soothing effect on the throat, relieving mild throat discomfort.

When combined with medications like Tuspel Syrup, these ingredients work together to help alleviate cough and cold symptoms by loosening mucus, suppressing the urge to cough, and soothing the throat.

Dosage & Administration of Tuspel Syrup

The recommended dosage for adults (12 years and over) using Tuspel Syrup is 2 teaspoonfuls (10 ml) every 6 hours. The maximum daily dose should not exceed 8 teaspoonfuls (40 ml).

You can take this medication with or without food, as directed by your doctor. If you are self-treating, make sure to follow all the instructions on the product package. If you have any questions, consult your doctor or pharmacist for clarification.

It is important to drink plenty of fluids while taking this medication. Adequate hydration helps to break up mucus and clear congestion.

The dosage of Tuspel Syrup is determined based on factors such as your age, medical condition, and response to treatment. It is important not to exceed the recommended dose or take the drug more frequently than directed.

If you are using the liquid form of the medication, be sure to measure the dose accurately using a special measuring device or spoon. Household spoons are not precise and may not provide the correct dose.

Interaction

Guaifenesin+Dextromethorphan+Menthol can potentially interact with several drugs. Here are some important drug interactions to be aware of:

Drug-Drug Interactions: Guaifenesin+Dextromethorphan+Menthol may interact with the following medications:

• Anti-allergic drugs: Such as diphenhydramine and cetirizine.
• Antidepressants: Such as duloxetine, sertraline, and escitalopram.
• Narcotic analgesic: Codeine.
• Opioids: Methadone.
• Antipsychotics: Haloperidol and quetiapine.
• Antifungal medication: Terbinafine.
• Antianxiety drugs: Alprazolam, clonazepam, and diazepam.
• Medicines used to treat irregular heartbeat: Quinidine and amiodarone.
• Anticonvulsants: Pregabalin.
• Central nervous system stimulant: Amphetamine.

It is important to inform your doctor about all the medications you are taking, including over-the-counter drugs and herbal supplements, to avoid potential interactions.

Drug-Food Interactions: Avoid consuming alcohol while taking Guaifenesin+Dextromethorphan+Menthol. Alcohol may increase the risk of side effects such as drowsiness or dizziness.

Drug-Disease Interactions: Guaifenesin+Dextromethorphan+Menthol should be used with caution in the following conditions:

• Asthma, chronic obstructive pulmonary disease (COPD), or emphysema.
• High blood pressure (hypertension).
• Epilepsy (fits).
• Glaucoma (a condition caused by increased pressure inside the eye).
• Liver diseases.
• Phenylketonuria (a birth defect resulting in the accumulation of phenylalanine (amino acid) in the body).

It is important to consult your doctor if you have any of these conditions before taking Guaifenesin+Dextromethorphan+Menthol to ensure its safe use.

Contraindications

If you are currently using a prescription monoamine oxidase inhibitor (MAOI) or have stopped using an MAOI within the past two weeks, it is important to avoid using Guaifenesin+Dextromethorphan+Menthol. MAOIs are medications used to treat depression, mental or emotional disorders, or Parkinson's disease.

Using Guaifenesin+Dextromethorphan+Menthol while taking or within two weeks of stopping an MAOI can result in serious and potentially life-threatening interactions. MAOIs can affect the way certain medications, including Guaifenesin+Dextromethorphan+Menthol, are metabolized in the body, leading to adverse effects.

If you are uncertain whether your prescription medication contains an MAOI, it is essential to consult your doctor or pharmacist before using Guaifenesin+Dextromethorphan+Menthol to ensure it is safe for you to use. They will be able to provide you with the necessary guidance and ensure that there are no potential interactions.

Pregnancy & Lactation

According to the classification by the U.S. Food and Drug Administration (FDA), Dextromethorphan Hydrobromide-Guaifenesin is categorized as pregnancy category C. This means that there are no well-controlled studies conducted on pregnant women, and the potential risks to the fetus are not fully known.

The use of Dextromethorphan Hydrobromide-Guaifenesin during pregnancy should only be considered if the benefits to the mother outweigh the potential risks to the unborn baby. It is important to discuss the use of this medication with your healthcare provider to weigh the potential benefits and risks based on your specific situation.

Regarding breastfeeding, there is no available information on the excretion of dextromethorphan-guaifenesin into human milk. It is unknown whether this medication passes into breast milk or its potential effects on the nursing infant. Therefore, the decision to continue or discontinue breastfeeding should be made in consultation with your healthcare provider.

As for menthol, there is limited information on its use during pregnancy. There have been no well-controlled studies conducted on pregnant women, and the potential risks of menthol to the fetus are unknown. It is recommended to consult with your healthcare provider before using products containing menthol during pregnancy.

Overall, it is important to discuss the use of any medication or product during pregnancy and breastfeeding with your healthcare provider to make informed decisions based on your individual circumstances and potential risks.

Precautions & Warnings

• It is important to follow the precautions and warnings associated with Guaifenesin+Dextromethorphan+Menthol and consult your doctor in specific situations. Here are some key points to consider:
• Asthma, chronic lung illness, shortness of breath: If you have any of these conditions, it is important to consult your doctor before using this product. They can evaluate your condition and determine if it is safe for you to use this medication.
• Persistent/chronic cough: If you have a persistent or chronic cough, it is advisable to seek medical advice before using this medication. Your doctor can determine the underlying cause of your cough and recommend appropriate treatment.
• Depression medication, particularly MAO inhibitors: If you are taking depression medication, especially monoamine oxidase (MAO) inhibitors, it is crucial to inform your doctor before using Guaifenesin+Dextromethorphan+Menthol. There may be potential interactions between these medications, and your doctor can provide guidance on their safe and appropriate use.
• Combination medicines containing similar ingredients: Many combination medicines contain guaifenesin, ammonium chloride, and sodium citrate. It is important to inform your doctor about all the medications you are taking, including Guaifenesin+Dextromethorphan+Menthol, to avoid overdosing on these ingredients.
• Drowsiness and sedatives: Guaifenesin+Dextromethorphan+Menthol may cause drowsiness. It is advisable to avoid taking this medication with other sedatives or medications used to treat depression, psychosis, or behavioral problems. These combinations can enhance the sedative effects and increase the risk of excessive drowsiness.
• Duration of use: It is important to use Guaifenesin+Dextromethorphan+Menthol for the recommended duration as directed by your doctor or as mentioned on the product label. Do not exceed the recommended dosage or use it for a longer duration without medical advice.
• Consult a doctor for lack of improvement or certain symptoms: If your symptoms do not improve or if you experience fever, rash, or persistent headache within 7 days of using this medication, it is advisable to stop using it and consult a doctor. These symptoms may indicate an underlying condition that requires further evaluation and appropriate treatment.
• Always follow the instructions provided by your healthcare provider or as mentioned on the product packaging. If you have any concerns or questions about using Guaifenesin+Dextromethorphan+Menthol, consult your doctor or pharmacist for personalized advice.

Storage Conditions

Keep out of children's reach. Store in a cool, dry place. Keep out of direct sunlight.