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Siloflo is used for the treatment of enlargement of the prostate gland, a medical condition known as benign prostatic hyperplasia (BPH).
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✅ Description:
Silodosin
- Treatment of benign prostatic hyperplasia (BPH), a condition characterized by an enlarged prostate gland.
- Symptoms Addressed: Difficulty in passing urine, frequent urination, increased frequency of urination at night, and inability to empty the bladder.
- Causes muscle relaxation of the prostate gland, urethra, and lower urinary bladder, improving urine flow and easing BPH symptoms.
- Take Siloflo as prescribed by your doctor. It should be taken daily at the same time to maximize benefits.
- Generally, side effects subside over time, but if they persist, consult your doctor.
- Inform your doctor about your detailed medical history before using Siloflo.
- Taking the medicine regularly and at the same time each day helps achieve the best results.
- Always seek medical advice if you experience persistent or severe side effects.
Safety Advices
Alcohol
UNSAFE
Consuming alcohol while taking Siloflo Capsule can increase dizziness. Therefore, avoid alcohol consumption while on this medicine.
Pregnancy
UNSAFE
Siloflo capsules should not be taken by any pregnant woman in any case.
Breastfeeding
UNSAFE
The use of Siloflo Capsule is contraindicated for nursing mothers.
Driving
UNSAFE
Siloflo Capsule can cause dizziness or fainting. If you are taking this medicine avoid driving.
Kidney
CONSULT YOUR DOCTOR
Siloflo 8mg Tablet should be used with caution in patients having kidney disease. Consult your doctor before taking it.
Liver
CONSULT YOUR DOCTOR
Siloflo 8mg Tablet should be used with caution in patients having severe liver disease. Consult your doctor before taking it.
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✔️ Uses of Siloflo 8mg Capsule
- Benign prostatic hyperplasia
✔️ How does Siloflo 8mg Capsule work?
It works by causing muscle relaxation of the prostate gland, part of the urethra inside the prostate, and the lower part of the urinary bladder which results in an improvement in the urine flow in patients with benign prostatic hyperplasia.
✔️ Side Effects of Siloflo 8mg Tablet
Common adverse reactions include retrograde ejaculation, dizziness, diarrhea, orthostatic hypotension, headache, nasopharyngitis, and nasal congestion.
✔️ Quick Suggestions:
- Silodosin helps in relieving the symptoms of an enlarged prostate. It does not decrease the size of the prostate.
- Urinate as soon as you feel the urge.
- Silodosin must be taken with food.
- You will feel better within hours or days of starting the treatment. The full effect is usually seen within 2 weeks.
- Silodosin may cause dizziness or sleepiness. Do not drive or do anything requiring concentration until you know how it affects you.
- If you are scheduled to undergo eye surgery due to cataracts or glaucoma, inform your eye doctor about the usage of Silodosin.
- Inform your doctor if you have ever been diagnosed with kidney or liver problems.
✔️ Indication
- Primary Use: Treatment of signs and symptoms of benign prostatic hyperplasia (BPH).
- Effectiveness: Highly effective for BPH treatment, especially for patients not responding to Tamsulosin.
- Unique Features: This does not cause orthostatic hypotension and offers convenient once-daily dosing.
✔️ Pharmacology
Silodosin selectively antagonizes post-synaptic alpha-1 adrenoreceptors in the prostate, bladder base, bladder neck, prostatic capsule, and prostatic urethra, leading to smooth muscle relaxation and improved urine flow.
✔️ Dosage & Administration:
- Standard Dose: 8 mg orally once daily with a meal.
- Moderate Renal Impairment: 4 mg orally once daily with a meal.
- Geriatric Patients: No significant differences in safety or effectiveness; orthostatic hypotension observed more frequently in older patients.
- Renal Impairment: Contraindicated in severe impairment; dose adjustment needed for moderate impairment.
- Hepatic Impairment: Contraindicated in severe impairment; no adjustment needed for mild to moderate impairment.
✔️ Interaction
Caution with strong P-glycoprotein inhibitors (e.g., cyclosporine) and PDE5 inhibitors, which may cause symptomatic hypotension.
✔️ Contraindications
- Severe Renal & Hepatic Impairment: Not recommended.
- Strong CYP3A4 Inhibitors: Avoid use with drugs like ketoconazole, clarithromycin, itraconazole, and ritonavir.
- Hypersensitivity: Not for patients with known hypersensitivity to Silodosin.
✔️ Pregnancy & Lactation
- Pregnancy Category B: Not indicated for use in women.
- Animal Studies: No significant teratogenic effects at high doses in animal studies.
✔️ Precautions & Warnings
- Postural Hypotension: May develop when beginning treatment.
- Cataract Surgery: Inform the ophthalmologist of Siloflo use due to the risk of Intraoperative Floppy Iris Syndrome (IFIS).
- Pediatric Use: Not indicated for use in pediatric patients.
✔️ Storage:
Store below 30°C in a dry place protected from light. Keep out of reach of children.
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