Tirzepatide is a prescription injectable medicine that can support blood glucose management and weight management when used together with appropriate diet and physical activity.
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Tirzepatide is an injectable prescription medicine used to improve blood sugar control in adults with type 2 diabetes. It is also used for chronic weight management in eligible adults with obesity or overweight accompanied by weight-related medical conditions.
Tirzepatide is generally administered once weekly, on the same day each week, at any time of day and with or without food. It should be used alongside a reduced-calorie diet and increased physical activity.
Common side effects may include nausea, vomiting, diarrhoea, decreased appetite, constipation, indigestion, and abdominal discomfort, particularly when treatment is started or the dose is increased. Severe or persistent abdominal pain, especially if it radiates to the back, may require immediate medical attention because it can be a sign of pancreatitis. Seek urgent medical attention if symptoms of a serious allergic reaction occur.
Tirzepatide should not be used in people with a personal or family history of medullary thyroid carcinoma (MTC) or in patients with Multiple Endocrine Neoplasia syndrome type 2 (MEN 2). Inform your doctor if you have a history of pancreatitis, severe gastrointestinal disease, kidney problems, or other significant medical conditions.
Tirzepatide delays gastric emptying and may affect the absorption of some oral medicines. Tell your doctor or pharmacist about all medicines and supplements you are taking.
If you are pregnant, planning to become pregnant, or breastfeeding, consult your healthcare provider before using tirzepatide.
Obesity is a condition characterised by excessive accumulation of body fat that may increase the risk of conditions such as type 2 diabetes, high blood pressure, cardiovascular disease, and certain cancers. Management may include dietary changes, regular physical activity, behavioural modifications, and prescription medicines when appropriate.
Type 2 diabetes mellitus is a chronic condition in which the body does not use insulin effectively and may not produce enough insulin to maintain normal blood glucose levels. Common symptoms can include increased thirst, frequent urination, increased hunger, fatigue, blurred vision, and slow wound healing.
Tirzepatide is used as an adjunct to diet and exercise to improve glycemic control in adults with type 2 diabetes mellitus. It enhances the incretin response and may produce clinically meaningful reductions in blood glucose and HbA1c levels.
Tirzepatide may be used for chronic weight management in eligible adults with obesity or overweight accompanied by weight-related medical conditions. By reducing appetite and increasing satiety, it can support reduced-calorie food intake and weight loss when combined with diet and physical activity.
Using tirzepatide together with insulin or sulfonylureas may increase the risk of hypoglycemia. Your doctor may adjust the dose of these medicines and recommend closer blood glucose monitoring.
Because tirzepatide delays gastric emptying, it may affect the absorption of some medicines taken by mouth. Inform your doctor or pharmacist about all oral medications you use.
Tirzepatide may reduce the effectiveness of oral hormonal contraceptives, particularly after treatment initiation and dose escalation. Discuss appropriate contraceptive options with your healthcare provider. Additional or non-oral contraception may be recommended during these periods.
Keep out of the reach and sight of children. Store in a refrigerator at 2°C to 8°C. Do not freeze; protect from light. Do not use if it has been frozen. To be taken and sold only on the prescription of a registered physician.
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