Glucozid 80mg Tablet | Gliclazide | Uses | Interaction | Price | ePharma
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Glucozid 80mg Tablet

Generic: Gliclazide

Type: Tablet

Pack Size: 10 Pcs

Glucozid 80mg Tablet/Gliclazide is used to treat maturity-onset diabetes, and diabetes with or without obesity in adults when diet, exercise, weight loss, or insulin therapy fail to provide adequate results.


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Discount Price: ৳ 74.4
MRP: ৳ 80 7% Off

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✅ Description:

  • Glucozid 80mg Tablet, containing Gliclazide, falls under the category of antidiabetic agents. This medication is primarily used to treat Type II diabetes mellitus in adults, especially when lifestyle changes, diet, and exercise alone do not yield sufficient results in controlling blood sugar levels.
  • Type II diabetes mellitus is a chronic condition characterized by elevated blood glucose levels. It occurs due to either inadequate production of insulin by the pancreas or reduced sensitivity of body cells to the actions of insulin.
  • As part of the treatment with Glucozid 80mg Tablet, your doctor may recommend adopting a healthier lifestyle, including maintaining a balanced diet, engaging in regular physical exercise, and refraining from alcohol consumption.
  • Before starting Glucozid 80mg Tablet, it's important to inform your doctor about any pre-existing liver or kidney issues. Additionally, if you have hormonal problems, genetic disorders like G6PD deficiency, or if you're malnourished or on an irregular diet, you should discuss this with your doctor as well.
  • Glucozid 80mg Tablet is not suitable for individuals with type I diabetes mellitus. If you are pregnant, planning to become pregnant, or breastfeeding, consult your doctor before taking this medication.
  • As always, it's crucial to follow your doctor's guidance and recommendations closely when using medications to effectively manage your health condition.

Safety Advices


Alcohol
UNSAFE

It is unsafe to consume alcohol with Glucozid 80mg Tablet as it affects blood glucose levels.


Pregnancy
CONSULT YOUR DOCTOR

Glucozid 80mg Tablet is usually not advised during pregnancy because it might have significant side effects on your fetus. However, if you are pregnant your doctor may prescribe alternative medicine with the same medicinal effect.


Breastfeeding
CONSULT YOUR DOCTOR

Avoid using Glucozid 80mg Tablet if you are breastfeeding. There is no sufficient information available to know whether this medicine can pass into your breast milk. Your doctor may prescribe a safer alternative with the same medicinal effect based on your clinical condition.


Driving
CAUTION

Glucozid 80mg Tablet may occasionally reduce your blood sugar levels, which may impair your concentration and your ability to perform these activities.


Kidney
CONSULT YOUR DOCTOR

Glucozid 80mg Tablet is not recommended for use in patients with severe kidney disease. It should be used with caution in patients with decreased kidney functions. Therefore, consult your doctor before taking it.


Liver
CONSULT YOUR DOCTOR

Glucozid 80mg Tablet is not recommended for use in patients with severe liver disease. It should be used with caution in patients with decreased liver functions. Therefore, consult your doctor before taking it.

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✔️ Uses of Glucozid 80mg Tablet
  • Treats Type II diabetes mellitus in adults
✔️ How does Glucozid 80mg Tablet work?

Glucozid 80mg Tablet, containing gliclazide, effectively manages blood sugar levels by increasing insulin secretion from the pancreas. This hormone facilitates the breakdown of circulating glucose in the blood. Additionally, gliclazide enhances the body's sensitivity to insulin, aiding in the utilization of blood glucose, ultimately resulting in lowered blood sugar levels.

✔️ Side Effects of Glucozid 80mg Tablet
  • Dizziness
  • Nausea or vomiting
  • Confusion
  • Weakness
  • Sweating
  • Changes in vision
  • Decreased heartbeat
  • Stomach pain
  • Constipation
  • Skin rash
  • Elevated liver enzymes
  • Low blood sugar levels
✔️ Quick Suggestions:
  • Take it shortly before or with the first main meal of the day (usually breakfast). Avoid skipping meals.
  • Be careful while driving or operating machinery until you know how Gliclazide affects you.
  • It can cause hypoglycemia (low blood sugar level) when used with other antidiabetic medicines, alcohol, or if you delay or miss a meal.
  • Always carry some sugary food or fruit juice with you in case you experience hypoglycemic symptoms such as cold sweats, cool pale skin, tremors, and anxiety.
  • Your doctor may check your liver function regularly. Inform your doctor if you develop symptoms, such as abdominal pain, loss of appetite, or yellowing of the eyes or skin (jaundice).
✔️ Indication of Glucozid 80mg Tablet

Patients with maturity-onset diabetes mellitus (NIDDM) who require an oral hypoglycaemic medication should use gliclazide.

✔️ Pharmacology

Gliclazide is a sulfonylurea of the second generation with hypoglycemic and perhaps hematological effects. It reduces hepatic glucose output while stimulating insulin release from pancreatic -cells by promoting Ca+2 transport across the -cell membranes.

✔️ Dosage & Administration of Glucozid 80mg Tablet

For adults with Type 2 diabetes mellitus, the recommended dosage of Glucozid 80mg Tablet is as follows:

Immediate-Release Tablet:

  • Initially, start with 40-80 mg daily.
  • The dosage can be gradually increased up to a maximum of 320 mg daily if required.
  • If the daily dosage exceeds 160 mg, it is divided into two equal doses.

Modified-Release Tablet:

  • Begin with 30 mg once daily.
  • The dosage can be increased by 30 mg increments, up to a maximum of 120 mg daily.
  • The interval between dose increases should be at least 1 month.
  • For patients who do not respond well, the dose may be increased after 2 weeks.

It's important to take Glucozid 80mg Tablet before meals or as instructed by your physician. Swallow the tablet with a glass of water; do not crush or chew it.

Your doctor will determine the appropriate dose and duration of treatment based on factors such as your age, body weight, and the severity of your condition. It's essential to follow your doctor's recommendations and continue taking Glucozid 80mg Tablet for the prescribed duration to effectively manage your blood sugar levels.

✔️ Interaction

Gliclazide, the active ingredient in Glucozid 80mg Tablet, can interact with various drugs, foods, and medical conditions. Here's a summary of the potential interactions and precautions:

Drug-Drug Interactions:

  • Interactions with other medicines used to treat high blood sugar (oral antidiabetics, GLP-1 receptor agonists, or insulin) can lead to additive effects, potentially causing low blood sugar (hypoglycemia).
  • Antibacterial drugs like sulfonamides and clarithromycin can interact with Gliclazide, affecting blood sugar control.
  • Medications used for high blood pressure or heart failure like captopril and enalapril might interact with Gliclazide and affect blood sugar levels.
  • Drugs used to treat fungal infections such as miconazole and fluconazole can impact the metabolism of Gliclazide.
  • Medications for indigestion and ulcers like H2 receptor antagonists (e.g., ranitidine) might alter Gliclazide's effects.
  • Monoamine oxidase inhibitors (MAOIs) used for depression, like selegiline and phenelzine, can interact with Gliclazide.
  • Painkillers, anti-inflammatories (ibuprofen, phenylbutazone), and glucocorticoids (hydrocortisone, prednisolone) can influence Gliclazide's effects.
  • Blood thinners/anticoagulants like warfarin can interact with Gliclazide, affecting blood clotting.
  • Medicines containing alcohol can cause interactions with Gliclazide.

Drug-Food Interactions:

  • Alcohol consumption can lead to an increased risk of hypoglycemia (low blood sugar) when taken with Gliclazide.

Drug-Disease Interactions:

  • Gliclazide should be avoided in individuals with severe liver or kidney problems, severe thyroid or adrenal gland issues, or those who have experienced a diabetic coma, as it may exacerbate their condition.
✔️ Contraindications
  • Allergy: If you have a known allergy to Gliclazide or any other ingredients in Glucozid 80mg Tablet, its use should be avoided.
  • Type 1 Diabetes: Glucozid 80mg Tablet is not suitable for individuals with type 1 diabetes, where the pancreas doesn't produce insulin.
  • Kidney or Liver Problems: If you have significant kidney or liver issues, caution is needed when using Glucozid 80mg Tablet, and its use might be contraindicated.
  • Ketones and Sugar in Urine: If you have ketones and sugar in your urine, it might indicate a serious imbalance in your diabetes control, and using Gliclazide might not be appropriate.
  • Diabetic Pre-coma or Coma: Glucozid 80mg Tablet should be avoided during states of diabetic pre-coma or coma, which are severe complications of diabetes.
  • Surgery, Trauma, Infections: During surgery, severe trauma, or infections, the use of Gliclazide might need to be reevaluated due to potential disruptions in blood sugar control.
  • Hereditary Disease - Porphyria: If you have the hereditary disease porphyria, the use of Glucozid 80mg Tablet might not be suitable.
  • Taking Miconazole: Concurrent use of Gliclazide with miconazole, a medication used to treat fungal infections, can lead to interactions and affect blood sugar control.
  • Breastfeeding: Gliclazide can pass into breast milk and potentially affect a breastfeeding infant, so its use is generally not recommended during breastfeeding.
✔️ Pregnancy & Lactation

Pregnant women should avoid taking gliclazide. It should not be used by a mother who is breastfeeding.

✔️ Precautions & Warnings
  • Gliclazide is not suitable for individuals with type 1 diabetes or those experiencing diabetic ketoacidosis, a serious complication of diabetes.
  • Gliclazide should not be taken if you are allergic to Gliclazide or any of its components.
  • If you have severe liver or kidney issues, Gliclazide's use should be avoided.
  • Gliclazide should be used with caution or avoided if you have severe thyroid or adrenal gland problems.
  • If you have experienced a diabetic coma in the past, Gliclazide might not be suitable for you.
  • Some diabetic patients taking Gliclazide may develop lactic acidosis, a rare but serious condition involving the accumulation of too much lactic acid in the blood. Proper liver and kidney function are necessary to eliminate excess lactic acid. It's essential to consult your doctor and take Gliclazide only under medical supervision.
  • Gliclazide is most effective when combined with healthy lifestyle changes such as weight loss, regular exercise, and a balanced diet.
✔️ Storage Conditions

Keep the temperature below 30°C and keep it away from light and moisture. Keep out of children's reach.

Frequently Asked Questions (FAQ)

Gliclazide and metformin are distinct medications despite both being used for type 2 diabetes. They have different mechanisms: Gliclazide boosts insulin secretion from the pancreas, while metformin enhances insulin efficiency within the body.

The amount of time required for Glucozid 80mg Tablet to show its action is 1-2 hours

The effect of Glucozid 80mg Tablet lasts for an average duration of 1 to 2 days.

Consume Gliclazide as directed by your doctor, ideally before meals. Scientific evidence suggests optimal effectiveness in controlling post-meal high blood sugar when taken 30 minutes before breakfast. If your regimen involves once-daily usage, take it in the morning with water before breakfast.

If you forget to take a dose of Glucozid 80mg Tablet, take it as soon as you remember. However, if it is time to take the next dose, skip the missed dose and take the next one at regular times. Do not take a double dose of Glucozid 80mg Tablet to compensate a missed dose, as it could lead to toxicity.

Co-administration of Glucozid 80mg Tablet with insulin is considered risky as they are increased chances of hypoglycemia (decreased blood sugar levels). Consult your doctor before taking it.

No. Glucozid 80mg Tablet is only prescribed for the treatment of type 2 diabetes also called as 'non-insulin-dependent diabetes'.

Glucozid 80mg Tablet is not recommended for use in children and adolescents (aged below 18 years).
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Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

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