Dimerol 80mg 14pcs

Indications

Dimerol 80 is a medication that is used to treat type 2 diabetes in adults. It belongs to a class of drugs known as sulfonylureas, and it helps diabetics control their blood sugar levels. This aids in the prevention of serious diabetes complications such as kidney damage and blindness.

Pharmacology

Dimerol 80 is a second-generation sulfonylurea with hypoglycemic and possibly hematological effects. By promoting Ca+2 transport across-cell membranes, it reduces hepatic glucose production while stimulating insulin release from pancreatic -cells.

Dosage & Administration

• The usual starting dose for a film-coated tablet is 40 to 80 mg daily. When necessary, the dose can be increased to 320 mg daily in divided doses. The medication should be taken before eating. Gliclazide is not used in children because it is contraindicated in juvenile-onset diabetes.
• Modified release preparation: Always take this medication exactly as directed by your doctor or pharmacist. If you are unsure, consult your doctor or pharmacist. The doctor determines the dose based on your blood and possibly urine sugar levels. Changes in external factors (weight loss, lifestyle, stress) or improvements in blood sugar control may necessitate gliclazide dose adjustments.
• The recommended daily dose is one to four tablets (up to 120 mg) taken at breakfast. This is determined by the patient's response to treatment. Gliclazide MR tablet is taken orally. At breakfast, take your tablet(s) with a glass of water (and preferably at the same time each day). Swallow your entire tablet(s) whole. Avoid chewing or crushing. You must always consume food after taking your tablet (s).
• If gliclazide is combined with metformin, an alpha-glucosidase inhibitor, thiazolidinedione, a dipeptidyl peptidase-4 inhibitor, a GLP-1 receptor agonist, or insulin, your doctor will determine the appropriate dose of each medicine for you. If you notice that your blood sugar levels are elevated despite taking your medication as directed, you should contact your doctor or pharmacist.
• If you take more Gliclazide tablets than is recommended: If you take too many tablets, immediately contact your doctor or the nearest hospital's Accident & Emergency department. Overdose symptoms include low blood sugar (hypoglycemia). The symptoms can be alleviated by immediately taking sugar (4 to 6 lumps) or sugary drinks, followed by a substantial snack or meal. If the patient becomes unconscious, notify a doctor immediately and dial 911. The same should be done if someone (for example, a child) has unintentionally taken the product. Food and drink should not be given to unconscious patients. It should be ensured that there is always someone who is well-informed and who can call a doctor in an emergency.
• If you forget to take your Gliclazide tablet: It is critical to take your medicine on a daily basis because regular treatment is more effective. If you forget to take a Gliclazide MR tablet, take the next dose at the regular time. Do not take a double dose to compensate for a missed dose.
• If you stop taking the Gliclazide MR tablet: Because diabetes treatment is typically lifelong, you should consult with your doctor before discontinuing this medication. Stopping could result in high blood sugar (hyperglycemia), which increases the risk of developing diabetes complications. If you have any additional questions about how to use this product, consult your doctor or pharmacist.

Interaction

Gliclazide's hypoglycemic effects may be enhanced by aspirin, NSAIDs, phenylbutazone, clofibrate, sulfonamide, cimetidine, imidazole antifungal medications, and monoamine oxidase inhibitors. Gliclazide's hypoglycemic effect may be reduced by Rifampin, Barbiturates, Phenytoin, Thiazide diuretics, Diazoxide, Glucocorticoids, Estrogens, Sympathomimetic medications, and Alcohol.

Contraindications

Dimerol 80 should not be used in the following situations:

• Diabetes of juvenile-onset (type 1)
• Diabetes is linked to ketosis.
• Diabetic patients undergoing surgery, following a serious injury, or during an infection
• Patients who are allergic to the sulfonylurea class of drugs
• Pregnant women and mothers who are breast-feeding
• Insufficiency of the liver

Side Effects

Hypoglycemia can occur in the presence of other diseases such as hepatic and renal dysfunction, starvation, and alcohol abuse. Headaches, gastrointestinal disturbances, nausea, dizziness, and skin responses such as rash, pruritus, and erythema are all possible side effects.

Pregnancy & Lactation

Pregnant women should avoid using gliclazide. It should not be used by a woman who is breastfeeding.

Precautions & Warnings

Gliclazide should be used with caution in people who have hepatic impairment. If there is clear evidence of liver disease, gliclazide should not be taken. Because gliclazide is thoroughly metabolized, it can be safely administered to patients with renal failure. Gliclazide is less likely to cause hypoglycemia than other sulfonylurea medications.

Storage Conditions

Store below 30°C and away from light in a cool, dry area.