Comet XR 1gm | Metformin Hcl | 1000mg | 6pcs | ePharma
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Comet XR 1gm 6pcs

Generic: Metformin Hydrochloride

Type: Tablet

Pack Size: 6 Pcs

Comet XR 1gm is a medicine used to treat type 2 diabetes mellitus and PCOS. It should be taken with food and requires regular monitoring of blood sugar and kidney function.


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✅ Description:

Metformin Hydrochloride is used to treat type 2 diabetes, a chronic condition that affects how the body processes glucose. It belongs to the class of anti-diabetic medications known as biguanides. METFORMIN is prescribed when diet and exercise alone have not been sufficient to control blood glucose levels.

Metformin Hydrochloride works by:

  1. Decreasing the amount of glucose absorbed from food.
  2. Reducing the amount of glucose produced by the liver.
  3. Increasing the body's sensitivity to insulin, a natural hormone that regulates blood glucose levels.

By controlling the amount of glucose in the blood, Metformin Hydrochloride helps manage diabetes and prevent complications associated with high blood sugar levels.

  • Do not take Metformin Hydrochloride if you are allergic to any of its components.
  • Consult your doctor if you are pregnant or breastfeeding before taking Metformin Hydrochloride.
  • Metformin Hydrochloride is considered safe for use in children over 10 years old if prescribed by a doctor.
  • Keep your doctor informed about your health conditions and any other medications you are taking to avoid potential side effects or interactions.

Safety Advices


Alcohol
UNSAFE

It is not safe to consume alcohol with Comet XR 1.


Pregnancy
CONSULT YOUR DOCTOR

Generally considered safe to use during pregnancy. Animal studies have shown minimal or no adverse effects on the developing baby, though human studies are limited.


Breastfeeding
CONSULT YOUR DOCTOR

Likely safe to use during breastfeeding. Limited human data suggest no significant risk to the baby.


Driving
CAUTION

Blood sugar fluctuations can affect your ability to drive. Do not drive if you experience these symptoms.


Kidney
CONSULT YOUR DOCTOR

Use with caution in patients with kidney disease. Dose adjustments may be necessary. Not recommended for patients with severe kidney disease. Regular kidney function monitoring is advised.


Liver
CAUTION

Use with caution in patients with liver disease. Dose adjustments may be necessary. Typically started at a low dose for patients with mild to moderate liver disease. Not recommended for severe liver disease.

Similar Products

✔️ Uses of Metformin Hydrochloride
  • Type 2 diabetes mellitus
  • Polycystic ovary syndrome (PCOS)
✔️ How does Metformin Hydrochloride work?

It lowers glucose production in the liver, delays sugar absorption from the intestines, and increases insulin sensitivity.

✔️ Common Side Effects of Metformin Hydrochloride
  • Nausea
  • Vomiting
  • Taste changes
  • Diarrhea
  • Abdominal pain
  • Loss of appetite
✔️ Quick Suggestions:
  • Prescribed to control blood sugar levels and reduce the risk of diabetic complications.
  • Less likely to cause weight gain and low blood sugar compared to other diabetes medications.
  • Carry a sugar source to manage potential low blood sugar levels.
  • Inform your doctor if you experience rapid breathing, persistent nausea, vomiting, or stomach pain, which may indicate lactic acidosis.
  • Long-term use may lead to vitamin B12 deficiency. Consult your doctor if you experience fatigue, pale skin, shortness of breath, or headache.
  • Regular monitoring of blood sugar levels and kidney functions is necessary.
✔️ Pharmacology

Metformin is an antihyperglycemic agent that decreases glucose production in the liver, delays glucose absorption from the intestines, and increases insulin sensitivity.

✔️ Dosage & Administration

Adult Dose

  • Type 2 Diabetes Mellitus:
    • Conventional Preparation: Start with 500 mg twice or thrice daily, or 850 mg 1-2 times daily. Gradually increase to 2000 mg daily. Maximum 2550 mg/day.
    • Modified-Release Preparation: Start with 500 mg once daily. Increase in increments of 500 mg to a maximum of 2000 mg once daily at night. If control is insufficient, split into 1000 mg twice daily.
  • Polycystic Ovary Syndrome (PCOS):
    • Start with 500 mg daily in the morning for 1 week, then 500 mg twice daily for 1 week, then 1.5-1.7 g/day in divided doses.

Child Dose

  • Type 2 Diabetes Mellitus (children >10 years): Start with 500 mg 1-2 times daily or 850 mg once daily. Gradually increase to a maximum of 2000 mg daily in divided doses.

Renal Dose

  • Check eGFR before starting metformin.
  • eGFR <30 mL/min/1.73 m²: Contraindicated.
  • eGFR 30-45 mL/min/1.73 m²: Not recommended to start treatment.
  • Monitor eGFR annually or more frequently in those at risk for renal impairment.
  • If eGFR falls below 45 mL/min/1.73 m², reassess risks and benefits.
  • Discontinue if eGFR falls below 30 mL/min/1.73 m².

Take the medicine as prescribed by your doctor. Swallow it whole with food. Do not chew, crush, or break it.

✔️ Interaction
  • Additive effects with sulfonylureas.
  • Thiazide diuretics, corticosteroids, phenothiazines, oral contraceptives, and others may worsen glycemic control.
  • ACE inhibitors may reduce fasting blood glucose.
  • Increased serum levels with cimetidine.
  • Potentially fatal interaction with iodinated contrast agents.
✔️ Contraindications
  • Acute or chronic metabolic acidosis.
  • Renal failure or severe renal impairment.
  • Severe liver impairment.
  • Conditions affecting renal function (e.g., dehydration, severe infection, shock).
  • Severe cardiac or respiratory conditions.
  • Pregnancy and lactation.
✔️ Pregnancy & Lactation

Pregnancy: Uncontrolled diabetes during pregnancy (gestational or permanent) is associated with an increased risk of congenital abnormalities and perinatal mortality. When the patient plans to become pregnant and during pregnancy, it is recommended that diabetes is not treated with metformin but that insulin be used to maintain blood glucose levels as close to normal as possible, to reduce the risk of malformations of the fetus.

Breastfeeding: Metformin is excreted into human breast milk. No adverse effects were observed in breastfed newborns/infants. However, as only limited data are available, breastfeeding is not recommended during metformin treatment. A decision on whether to discontinue breastfeeding should be made, taking into account the benefits of breastfeeding and the potential risk of adverse effects on the child.

✔️ Precautions & Warnings
  • Caution in patients with heart failure or those undergoing radiologic studies with iodinated contrast agents.
  • Monitor renal function regularly.
  • Not recommended during lactation.
✔️ Storage Conditions:

Store in a cool and dry place away from sunlight

Frequently Asked Questions (FAQ)

Comet XR 1gm increases the body's sensitivity to insulin and delays the absorption of sugar, which is essential for controlling blood sugar levels. Unlike other anti-diabetic medications like insulin or sulfonylureas, METFORMIN does not cause significant weight gain and may lead to modest weight loss. It is also the only recommended treatment for prediabetes. Additionally, Comet XR 1gm helps prevent serious diabetes-related complications such as diabetic retinopathy, nephropathy, and neuropathy and reduces the risk of heart attack and stroke.

No, Comet XR 1gm is only prescribed for the treatment of type 2 diabetes, also known as non-insulin-dependent diabetes. It is not used for the treatment of type 1 diabetes.

Your doctor will provide specific instructions on when to stop and restart Comet XR 1gm before and after major surgery to ensure safety and proper blood sugar management.

Before undergoing a CT scan or any procedure involving the injection of contrast materials containing iodine, consult your doctor. These procedures may affect kidney function, and your doctor may advise stopping METFORMIN temporarily.

Yes, you should consult your doctor before taking METFORMIN if you are already taking regular insulin.

Avoid excessive alcohol consumption while taking Comet XR 1gm as it can increase the risk of lactic acidosis, a life-threatening condition characterized by symptoms such as dizziness, drowsiness, muscle pain, and rapid shallow breathing.

If you forget to take a dose of Comet XR 1gm, take it as soon as you remember. Do not take a double dose to make up for the missed one, as this can cause your blood sugar levels to drop rapidly. Take the next dose at the usual scheduled time.

Comet XR 1gm is associated with either modest weight loss or stable body weight. If you experience excessive weight loss while taking Comet XR 1gm, inform your doctor promptly as your dosage may need adjustment.

Comet XR 1gm is used to treat type 2 diabetes mellitus. It helps lower blood glucose levels by decreasing the amount of glucose absorbed from food and reducing the amount of glucose produced by the liver.
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Check our pricing section for Comet XR 1gm 6pcs price in Bangladesh. After Submitting Order, You will receive a phone call for verification, price and delivery confirmation. We deliver inside/outside Dhaka (Delivery all over Bangladesh). We offer express/urgent medicine delivery inside Dhaka. Do not forget to check discount/cashback offers if you are eligible to avail any.

Disclaimer:
ePharma sole intention is to ensure that its consumers get proper information as musch as possible. Although we do not guarantee the accuracy and the completeness of the information that provided and here information is for informational purposes only. The information contained herein should NOT be used as a substitute for the advice of a qualified physician. This may not cover everything about particular health conditions, lab tests, medicines, all possible side effects, drug interactions, warnings, alerts, etc. Please consult your healthcare professional and discuss all your queries related to any disease or medicine. We intend to support, not replace, the doctor-patient relationship.

Pricing Information, Availability:
ePharma reserves the right to make adjustments to pricing, Products and Service offerings for reasons including, but not limited to, changing market conditions, Product discontinuation, Product unavailability, manufacturer price changes, supplier price changes and errors in advertisements. All orders are subject to Product availability and the availability of Personnel to perform the Services. Therefore, Seller cannot guarantee that it will be able to fulfill Customer’s orders. If Services are being performed on a time and materials basis, any estimates provided by Seller are for planning purposes only.

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