Clindax Plus Gel 15gm

Uses of Clindax Plus Gel

Treats Acne

How does Clindax Plus Gel work?

• Clindamycin: Inhibits the growth and multiplication of acne-causing bacteria on the skin.
• Tretinoin: Controls acne by preventing clogging of skin pores with sebum and dead skin cells, promoting skin renewal.

Side Effects of Clindax Plus Gel

Common:

• Skin redness, irritation, itching, burning, or stinging.
• Skin dryness, peeling, sensitivity to sunlight.

Uncommon:

• Increased sebum production.
• Skin rash, scaling, sunburn.
• Skin discoloration.

Rare:

• Stomach pain, nausea.
• Headache, eye irritation.
• Skin infections (cold sore).
• Loss of skin pigmentation.

Managing Side Effects:

• Use suitable moisturizers for skin rash.
• Avoid direct sunlight exposure; wear protective clothing.
• Consult the doctor for sunscreen recommendations.

When to Stop and Seek Medical Attention:

• Signs of allergic reactions.
• Severe or prolonged diarrhea with stomach cramps.
• Severe itching, burning, or peeling of the skin.

Quick Suggestions:

• Clindax Plus Gel should be applied as a thin layer onto clean, dry, unbroken skin affected by acne.
• Clean the area to be treated with water and a non-medicated soap, and let it dry for 20-30 minutes before applying the medicine.
• It may cause minor burning, stinging, or irritation when applied. Inform your doctor if this does not go away.
• Avoid contact with your eyes, nose, or mouth. Rinse it off with water if you accidentally get the cream in these areas.
• Avoid exposure to sunlight while using Clindamycin + Tretinoin as it increases the sensitivity of your skin. Use protective measures such as sun-cream or protective clothing.
• Inform your doctor if you are pregnant, planning pregnancy, or breastfeeding.

Clindax Plus Gel and Acne:

• Acne is a prevalent skin condition characterized by clogged hair follicles.
• Clogging occurs due to a combination of oil (sebum) and dead skin cells.
• Common acne manifestations include whiteheads, blackheads, and pimples.

Role of Clindax Plus Gel:

• Treatment Focus: Clindax Plus Gel is specifically designed for the treatment of acne.
• Active Ingredients:
  • Clindamycin (Lincosamide Antibiotic): Targets acne-causing bacteria.
  • Tretinoin: Normalizes skin cell growth, preventing follicular blockages.

Pharmacology

Clindax Plus Gel combines Clindamycin phosphate, a lincosamide antibiotic, and Tretinoin, to effectively address acne. The mechanism of action involves specific actions of each component:

Clindamycin (Lincosamide Antibiotic):

• Target: 50s ribosomal subunit of susceptible bacteria.
• Action: Binds to the ribosomal subunit, preventing the elongation of the peptide chain.
• Result: Interference with peptidyl transfer, suppressing bacterial protein synthesis.
• Specific Effect: Inhibits the activity of Propionibacterium acne, reducing acne occurrence.

Tretinoin:

• Action: Decreases the cohesiveness of follicular epithelial cells.
• Result: Increases turnover, facilitating the expulsion of comedones (clogged hair follicles).
• Specific Effect: Normalizes skin cell growth, shedding cells that clog hair follicles.

Combined Effect:

• Clindamycin: Targets bacterial growth, reducing acne-causing bacteria.
• Tretinoin: Addresses skin cell cohesiveness and turnover, preventing the accumulation of dead cells and promoting the expulsion of comedones.

Dosage & Administration:

• Topical use only; avoid application on inflamed, irritated, or sensitive skin areas.
• Do not use cosmetics or makeup before applying Clindax Plus Gel.
• May increase skin sensitivity to sunlight; use sunscreen and wear protective clothing outdoors.
• Inform the doctor of any other skin conditions, gut problems, family history of skin cancer, or if pregnant/breastfeeding.

Interaction

• Inform the doctor about the use of other skincare products, antibiotics, corticosteroids, muscle relaxants, or blood thinners.
• Overdosage may cause skin irritation, and stomach issues; consult a doctor if necessary.

Contraindications

Clindamycin and Tretinoin should not be administered to individuals who are hypersensitive to Clindamycin or Tretinoin or any other component of the Gel.

Pregnancy & Lactation

It is not known whether Clindamycin or Tretinoin is excreted in human milk. Exercise special caution while applying Clindamycin or Tretinoin to a nursing mother.

Precautions & Warnings

• Not recommended for pregnant/breastfeeding women.
• Avoid if allergic to Tretinoin, Clindamycin, or Lincomycin.
• Caution in chronic inflammatory bowel disease, colitis history, skin conditions, or family history of skin cancer.
• Consult before surgery, in pediatrics (12 years or older), and in geriatrics.

Storage Conditions

• Keep Clindax Plus Gel out of reach of children
• Store Clindax Plus Gel at room temperature
• Avoid contact with Clindax Plus Gel with eyes, ears, nose, or mouth. If contact happens accidentally, rinse it off with warm water