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Clindamycin+Tretinoin gel is indicated for the topical treatment of Acne vulgaris.
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✅ Description:
- Trunac Gel, a combination of Clindamycin and Tretinoin, is indicated for the management of acne in adults and adolescents aged 12 years or older.
- Clindamycin: A topical antibiotic that stops the growth and multiplication of acne-causing bacteria on the skin.
- Tretinoin: A synthetic vitamin A derivative that prevents skin pores from getting clogged with sebum and dead skin cells. It removes dead skin cells clogging hair follicles and helps the skin renew more quickly.
- Trunac Gel is for topical use only. Apply to affected areas as directed by your doctor.
- Avoid using inflamed, irritated, or sensitive skin areas.
- Do not use cosmetics or makeup products before applying Trunac Gel.
- Trunac Gel may make your skin more sensitive to sunlight. Use sunscreen and wear protective clothing when going outdoors.
- Inform your doctor if you have other skin conditions (e.g., rosacea, eczema), gut problems (e.g., ulcerative colitis), or a family history of skin cancer.
- Trunac Gel is not recommended for use in pregnant or breastfeeding women. Women of childbearing age must use suitable contraception to avoid pregnancy during therapy with Trunac Gel.
Safety Advices
Alcohol
UNSAFE
No interaction found/established
Pregnancy
CAUTION
Trunac Gel is not recommended for use in pregnant women. Therefore, inform your doctor before using Trunac Gel if you are pregnant or think you may be pregnant. Women of childbearing age must use a suitable contraceptive method to avoid pregnancy while undergoing therapy with Trunac Gel.
Breastfeeding
CONSULT YOUR DOCTOR
Trunac Gel is not recommended for use in breastfeeding women. Therefore, please consult your doctor before using it.
Driving
SAFE
No interaction found/established
Kidney
CONSULT YOUR DOCTOR
No interaction found/established
Liver
CONSULT YOUR DOCTOR
No interaction found/established
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✔️ Composition of Trunac Gel
Clindamycin+Tretinoin-1.2%+0.025%
✔️ Uses of Trunac Gel
- Acne
✔️ Side Effects of Trunac Gel
- Dryness
- Skin peeling
- Dermatitis
- Application site reactions (burning, irritation, itching and redness)
✔️ How does Trunac Gel work?
Trunac Gel is a combination of two medicines: Clindamycin and Tretinoin, which treat pimples (acne). Clindamycin is an antibiotic that works by penetrating the skin and killing acne-causing bacteria. Tretinoin is a form of vitamin A that reduces oil production in the skin, replenishes the skin, and helps keep your pores open.
✔️ Quick Suggestions:
- Trunac Gel should be applied as a thin layer onto clean, dry, unbroken skin affected by acne.
- Clean the area to be treated with water and a non-medicated soap, and let it dry for 20-30 minutes before applying the medicine.
- It may cause minor burning, stinging, or irritation when applied. Inform your doctor if this does not go away.
- Avoid contact with your eyes, nose, or mouth. Rinse it off with water if you accidentally get the cream in these areas.
- Avoid exposure to sunlight while using Trunac Gel as it increases the sensitivity of your skin. Use protective measures such as sun-cream or protective clothing.
✔️ Indication of Trunac Gel
Clindamycin and Tretinoin, which treats pimples (acne). Clindamycin is an antibiotic. Tretinoin is a form of vitamin A
✔️ Pharmacology
- Clindamycin: A lincosamide antibiotic that binds to the 50s ribosomal subunit of susceptible bacteria, preventing peptide chain elongation by interfering with peptidyl transfer. This suppresses bacterial protein synthesis and inhibits the activity of Propionibacterium acnes, reducing acne occurrence.
- Tretinoin: A retinoid that decreases the cohesiveness of follicular epithelial cells and increases cell turnover, bringing comedones out.
✔️ Dosage & Administration of Trunac Gel
- Evening: Wash the face gently with mild soap and water, then pat the skin dry. Apply the gel with fingertips gently over the face.
- Morning: Apply sunscreen after using the gel. Do not wash your face more than 2 or 3 times a day. Apply sunscreen as needed.
- Safety and effectiveness in children below 12 years of age have not been established.
- Consult your physician before using this medication.
✔️ Interaction
- Use caution when using other potentially irritating topical products (e.g., medicated or abrasive soaps, high alcohol content products, astringents, spices, or lime).
- Avoid concomitant use with Erythromycin, as it decreases the activity of both Clindamycin and Erythromycin.
- Use caution with neuromuscular medications as Clindamycin can enhance their activity.
✔️ Contraindications
Hypersensitivity to Clindamycin, Tretinoin, or any component of the gel.
✔️ Pregnancy & Lactation
It is unknown if Clindamycin or Tretinoin is excreted in human milk. Use with caution in nursing mothers.
✔️ Precautions & Warnings
Avoid applying Clindamycin and Tretinoin gel to the eyes, nose, ears, lips, cuts, burns, or other infections. Keep away from sunlight after application.
✔️ Storage Conditions:
Store below 25°C, away from light and moisture. Keep out of reach of children.
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