Clavusef 500mg Tablet 4pcs

Uses of Clavusef 500mg Tablet

• Pharyngitis/Tonsilitis
• Sinusitis
• Acute bronchitis
• Skin and soft tissue infections
• Urinary tract infections
• Lyme disease
• Acute bacterial otitis media

How does Clavusef 500mg Tablet work?

is a combination of cefuroxime and clavulanic acid. Cefuroxime is an antibiotic that works by preventing the formation of a protective coating on the bacteria, which is essential for their survival. Clavulanic acid is a beta-lactamase inhibitor that works by reducing resistance and enhancing the activity of cefuroxime against bacteria.

Side Effects of Clavusef 500mg Tablet

• Diarrhea
• Headache
• Difficult or painful urination
• Change in taste
• Abdominal pain
• Acid or sour stomach

Quick Suggestions:

• Take Clavusef 500mg Tablet as prescribed without skipping any doses. Finish the full course of treatment, even if you start feeling better. Stopping the medication early may cause the infection to return and become more difficult to treat.
• Take the medicine with food to prevent an upset stomach.
• Diarrhea may occur as a side effect. Taking probiotics can help alleviate this. If you notice bloody stools or develop abdominal cramps, contact your doctor.
• Include fiber-rich foods in your diet, such as whole grains, beans, lentils, berries, broccoli, peas, and bananas. This can help manage diarrhea and promote healthy digestion.
• Avoid consuming foods rich in calcium, grapefruit, and grapefruit juice, as they may interfere with the absorption of antibiotics.
• It is recommended to avoid alcohol consumption during the treatment period to ensure effective treatment.
• Avoid using tobacco products.
• If you develop an itchy rash, swelling of the face, throat, or tongue, or experience difficulty breathing while taking the medication, stop using it immediately and inform your doctor.
• Do not use any leftover medicine to treat future infections. Always consult your doctor before taking any antibiotics for a new infection.

Indication of Clavusef 500mg Tablet

Clavusef 500mg Tablet is used to treat various bacterial infections like infections of the urinary tract, respiratory tract, and sexually transmitted diseases.

Pharmacology

Cefuroxime is a bactericidal antibiotic belonging to the second generation of cephalosporins. It has a broad spectrum of activity against various Gram-positive and Gram-negative bacteria, including strains that produce beta-lactamase enzymes. Cefuroxime works by interfering with the process of transpeptidation, which is involved in the production of bacterial cell walls. By disrupting this process, it effectively kills the bacteria.

Clavulanic acid, derived from Streptomyces clavuligerus, is a beta-lactamase inhibitor. It has a structural similarity to beta-lactam antibiotics and acts by irreversibly binding to and inactivating beta-lactamase enzymes. Beta-lactamase enzymes are produced by certain bacteria to break down and inactivate beta-lactam antibiotics, making them ineffective. Clavulanic acid, when combined with cefuroxime, protects cefuroxime from degradation by beta-lactamase enzymes. This combination provides a therapeutic option for bacterial infections caused by bacteria resistant to beta-lactam antibiotics.

Dosage & Administration of Clavusef 500mg Tablet

For adolescents and adults (13 years and older):

• Pharyngitis/tonsillitis: Take 250 mg twice daily for 5-10 days.
• Acute bacterial maxillary sinusitis: Take 250 mg twice daily for 10 days.
• Acute bacterial exacerbation of chronic bronchitis: Take 250-500 mg twice daily for 10 days.
• Secondary bacterial infections of acute bronchitis: Take 250-500 mg twice daily for 5-10 days.
• Uncomplicated skin and skin structure infections: Take 250-500 mg twice daily for 10 days.
• Uncomplicated urinary tract infections: Take 250 mg twice daily for 7-10 days.
• Uncomplicated Gonorrhoea: Take 1000 mg twice daily as a single dose.
• Community-acquired pneumonia: Take 250-500 mg twice daily for 5-10 days.
• MDR Typhoid Fever: Take 500 mg twice daily for 10-14 days.
• Early Lyme disease: Take 500 mg twice daily for 20 days.

For pediatric patients (3 months to 12 years):

• Pharyngitis/tonsillitis: Take 20 mg/kg/day divided into two doses for 5-10 days.
• Acute otitis media: Take 30 mg/kg/day divided into two doses for 10 days.
• Acute bacterial maxillary sinusitis: Take 30 mg/kg/day divided into two doses for 10 days.
• Impetigo: Take 30 mg/kg/day divided into two doses for 10 days.

Please note that these dosages and durations are general guidelines and may vary depending on individual factors. Swallow the medicine with a glass of water. Do not crush or chew the medicine. Your physician will determine the correct dose and duration of Clavusef 500mg Tablet for you depending on your age, body weight, and disease condition.

Interaction

Clavusef 500mg Tablet may interact with certain medications. It is important to inform your doctor if you are taking any of the following medications:

• Antacids such as esomeprazole and omeprazole
• Anticoagulants like warfarin
• Anti-gout medications such as probenecid
• Diuretics like furosemide
• Oral contraceptives containing estrogen and progesterone

Additionally, it is important to inform your doctor if you have any of the following conditions:

• Colitis, which is inflammation in the lining of the colon
• Seizures
• Undergoing dialysis treatment
• Kidney or liver dysfunction

By providing this information, your doctor can assess the potential interactions and make any necessary adjustments to your treatment plan.

Contraindications

If you have a known hypersensitivity or allergy to cephalosporins, including cefuroxime, you should not take Clavusef 500mg Tablet or any other medication containing cephalosporins. It is important to inform your doctor about your allergy so that alternative medications can be prescribed if necessary. Allergic reactions to cephalosporins can range from mild skin rashes to severe reactions such as anaphylaxis, which is a life-threatening condition

Pregnancy & Lactation

It is generally recommended to avoid the use of antibiotics, including cefuroxime-clavulanic acid, during the first trimester of pregnancy if possible. However, in later stages of pregnancy, cefuroxime-clavulanic acid can be considered safe for treating certain infections, including urinary tract infections, when the potential benefits outweigh the potential risks. It is important to consult with your healthcare provider who can assess your specific situation and provide appropriate guidance.

Regarding breastfeeding, cefuroxime-clavulanic acid is excreted in small amounts in breast milk. While the risk of sensitizing the child to the medication should be taken into consideration, the decision to use cefuroxime-clavulanic acid while breastfeeding should be made in consultation with a healthcare professional. They can weigh the benefits of treatment against any potential risks and help you make an informed decision.

Precautions & Warnings

Before initiating treatment with Clavusef 500mg Tablet, it is important to inform your doctor about any allergies you may have, especially related to antibiotics. Additionally, if you have kidney or liver problems, it is crucial to discuss this with your doctor before taking the medication.

Self-medication with Clavusef 500mg Tablet should be avoided, as it can contribute to the development of antibiotic resistance, where antibiotics become less effective against specific bacterial infections. It is always advisable to consult a doctor before starting any medication.

If you have colitis, which is inflammation of the colon, it is important to consult your doctor before taking Clavusef 500mg Tablet, as caution may be required.

In patients receiving concurrent treatment with potent diuretics, Clavusef 500mg Tablet should be used with caution. It is recommended to consult with your doctor if you are taking potent diuretics along with Clavusef 500mg Tablet.

If you are pregnant or planning for pregnancy, it is important to consult your doctor before taking Clavusef 500mg Tablet. Similarly, if you are breastfeeding, it is advisable to avoid taking Clavusef 500mg Tablet as it may pass into breast milk.

To prevent unpleasant side effects, it is recommended to avoid alcohol consumption while taking Clavusef 500mg Tablet.

Storage Conditions

Store Clavusef 500mg Tablets at room temperature, protected from light and moisture. Keep out of reach of the children and pets.