Indications
Melasma can be treated with Spotclen Cream. It is a skin-lightening medication that makes darkened skin spots and patches lighter (hyperpigmentation). It lessens the skin's melanin content, a pigment that darkens the skin. It aids in the skin's reversible depigmentation.
Pharmacology
A topical depigmenting medication called hydroquinone prevents the enzymatic oxidation of tyrosine to 3,4-dihydroxyphenylalanine and suppresses the metabolic activities of melanocytes, leading to reversible skin depigmentation.
Dosage & Administration
Contraindications
Hydroquinone is contraindicated to patients with prior history of hypersensitivity or allergic reaction to hydroquinone or other ingredients in the preparation.
Side Effect
There have been no reports of systemic side effects. Hypersensitivity (localized contact dermatitis) may develop from time to time, in which case the drug should be stopped.
Pregnancy & Lactation
Pregnancy Classification C. Either animal research has indicated negative effects on the fetus (teratogenic, embryocidal, or other) and no controlled studies in women have been conducted, or studies in women and animals are not accessible. Only if the possible benefit outweighs the risk to the fetus should drugs be administered.
It is unknown if topical hydroquinone is absorbed or eliminated in human milk during lactation. When a nursing mother uses topical hydroquinone, caution is suggested.
Precautions & Warnings
Storage Conditions
Store between 20-25° C. Protects from light.
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