Manufacturer/Distributor: Ambee Pharmaceuticals Ltd.
Generic Name: Nitrazepam 5mg/tablet.
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Noctin 5 is a prescription medicine used for treating insomnia. It is generally used in combination with other medicines. It relaxes the brain and helps to treat people who have problems with their sleeping habits. Noctin 5 may be taken with or without food. However, take it at the same time each day as this helps to maintain a consistent level of medicine in the body. Take this medicine in the dose and duration as advised by your doctor as it has a high potential of habit-forming. If you have missed a dose, take it as soon as you remember and finish the full course of treatment even if you feel better. It is important that this medication is not stopped suddenly without talking to your doctor as it may cause nausea and anxiety. It should only be used for a limited period as long term use of this medicine is not recommended. Noctin 5 may cause dizziness and sleepiness as side effects of this medicine, so do not drive if you have taken this medicine. Moreover, driving under the influence of this medicine is also considered as an offense. Other common side effects of this medicine include unsteadiness and impaired coordination. These are usually temporary and resolve on their own. Please consult your doctor if these side effects bother you or do not go away. This medicine may cause weight gain also. Thus, it is better to eat a healthy balanced diet and exercise regularly. It should be noted that in elderly patients this medicine may reduce the muscle tone and increased risk of falls. You should avoid alcohol intake while taking this medicine as it will increase drowsiness.
Uses of Noctin 5
Side effects of Noctin 5
Common
How to use Noctin 5
Take this medicine in the dose and duration as advised by your doctor. Swallow it as a whole. Do not chew, crush or break it. Noctin 5 may be taken with or without food, but it is better to take it at a fixed time.
How Noctin 5 works
Noctin 5 is a benzodiazepine. It works by increasing the action of a chemical messenger (GABA) which suppresses the abnormal and excessive activity of the nerve cells in the brain.
What if you forget to take Noctin 5?
If you miss a dose of Noctin 5, take it as soon as possible. However, if it is almost time for your next dose, skip the missed dose and go back to your regular schedule. Do not double the dose.
Quick Tips
Brief Description
Indication
Insomnia
Administration
May be taken with or without food.
Adult Dose
Oral Short-term management of insomnia Adult: 5 mg at night; increase to 10 mg if necessary. Elderly: and debilitated patients: ?normal adult dose.
Child Dose
Oral Infantile spasms Child: Infants: 125 mcg/kg bid; gradually increase to 250-500 mcg/kg bid.
Contraindication
Myasthenia gravis, narrow-angle glaucoma, severe respiratory insufficiency, sleep apnoea syndrome, severe hepatic impairment, porphyria.
Mode of Action
Nitrazepam is a benzodiazepine with a pronounced sleep-inducing activity. It depresses the reticular-activating system in the brainstem by enhancing the inhibitory effect of GABA on brain cells, thus preventing excessive brain activity.
Precaution
May induce anterograde amnesia; caution patients to have uninterrupted sleep of 7-8 hr after ingestion of dose. May impair ability to drive or operate machinery. Depression, especially if suicidal risk may be present. History of drug abuse or acute alcoholism. Hepatic and renal impairment. Respiratory disease. Debilitated patients. Patients who are at risk of falls. Children, elderly. Pregnancy and lactation.
Side Effect
Hypotension, palpitation; agitation, aggressiveness, amnesia, ataxia, confusion, delusions, disorientation, dizziness, fatigue, hallucination, hangover, headache, irritability, nightmares, psychoses, rage, restlessness, sedation; rash; changes in libido; constipation, diarrhoea, excessive salivation, heartburn, nausea, vomiting; granulocytopenia, leukopenia; falling, muscle weakness; blurred or double vision; tinnitus (associated with withdrawal); aspiration, increased bronchial secretion, dyspnoea.
Interaction
CNS depressant effect increased with alcohol, barbiturates, TCAs, phenothiazines, morphine derivatives. Effects may be antagonised by theophylline. Increased levels/effects with probenecid. Reduced levels/effects with rifampicin. May reduce effects of levodopa.
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